Publication Year: 1973
DOI: https://doi.org/10.1172/jci107332
Abstract: To assess family about 6% of survivors in both age groups. studies were carried out in 2520 relatives and spouses the of 176 survivors of myocardial infarction, including 149 hyperlipidemic and genetics 27 normolipidemic individuals. The distribution of fasting plasma cholesterol and of triglyceride values in relatives, together with segregation Show more
Authors:
Publication Year: 1976
DOI: https://doi.org/10.1126/science.822515
Abstract: These studies hyperlipidemia effects of chronic hyperlipidemia are complex in that the condition causes results not only in the deposition of lipids in the progressive atheromatous lesions but that it may produce the primary endothelial atherosclerosis. injury that initiates the process of atherosclerosis as well. It has been shown that Show more
Authors:
Publication Year: 2012
DOI: https://doi.org/10.1016/j.pop.2012.11.003
Abstract: Not available
Authors:
Publication Year: 2014
DOI: https://doi.org/10.1056/nejmoa1316222
Abstract: Evolocumab, a 9 atorvastatin at a dose of 80 mg daily plus ezetimibe (PCSK9), at a dose of 10 mg daily, for a run-in significantly period of 4 to 12 weeks. Patients with an LDL reduced cholesterol level of 75 mg per deciliter (1.9 mmol per low-density liter) or higher Show more
Authors:
Publication Year: 1982
DOI: https://doi.org/10.1161/01.atv.2.2.87
Abstract: olyunsaturated fatty essential to the growth and proper nutrition of humans and acids animals.In recent years, however, these fatty acids have been used In to treat and prevent atherosclerosis, and, on an experimental basis, the to inhibit thrombosis.It should be emphasized that these additional uses diet are not at all Show more
Authors:
Publication Year: 2006
DOI: https://doi.org/10.1073/pnas.0506982103
Abstract: Farnesoid X bile of its central roles in coordinating regulation of both glucose acid and lipid metabolism, we propose that FXR agonists are promising and therapeutic agents for treatment of diabetes mellitus. cholesterol homeostasis. Here we demonstrate that FXR receptor also regulates glucose metabolism. Activation of FXR by the synthetic Show more
Authors:
Publication Year: 2010
DOI: https://doi.org/10.1161/circulationaha.110.961714
Abstract: Background— Inflammation in lesion formation. In turn, neutropenic mice display reduced plaque sizes the at early but not late stages of atherosclerotic lesion formation. development Flow cytometry of enzymatically digested aortas further shows altered cellular of plaque composition in neutropenic mice with reduced numbers of inflammatory atherosclerosis. monocytes and macrophages. Show more
Authors:
Publication Year: 2017
DOI: DOI not available
Abstract: Cardiovascular disease adults many patients require adjunct therapies to properly control hyperlipidemia including in niacin, bile acid sequestrants, fibric acids, and ezetimibe. FH can the be even more challenging to treat, often requiring the use United of lomitapide, mipomersen, proprotein convertase subtilisin/kexin type 9 inhibitors, or States, low-density lipoprotein cholesterol Show more
Authors:
Publication Year: 1973
DOI: DOI not available
Abstract: A B and Elevation in triglyceride levels with (7.8%) or without (15.6%) an triglyceride associated elevation in cholesterol levels was three times more common levels in survivors than a high cholesterol level alone (7.6% ). were These results raise the possibility that hypertriglyceridemia may be as measured an important a Show more
Authors:
Publication Year: 1995
DOI: https://doi.org/10.1161/01.cir.92.11.3172
Abstract: Background Hypercholesterolemia platelet patients. Thrombus formation was assessed by exposing porcine aortic media reactivity to the patient’s flowing venous blood for 3 minutes at is a shear rate of 754 or 2546 s −1 at increased 37°C in an ex vivo superfusion chamber. Quantitative morphometric platelet with thrombus formation at Show more
Authors:
Publication Year: 2000
DOI: https://doi.org/10.1001/archinte.160.13.2050
Abstract: Background
Although in associated with the development of hyperglycemia, hyperlipidemia, and lipodystrophy. Methods
patients A 5-year historical cohort analysis in a population of 221 with HIV-infected patients observed in the Infectious Diseases Clinic of a advanced tertiary care center from October 1, 1993, through July 31, HIV 1998. Clinical and Show more
Authors:
Publication Year: 2004
DOI: https://doi.org/10.7326/0003-4819-140-10-200405180-00006
Abstract: Background: Low-carbohydrate evidence and tolerability. Results: A greater proportion of the low-carbohydrate diet on group than the low-fat diet group completed the study (76% their vs. 57%; P = 0.02). At 24 weeks, weight loss effectiveness. was greater in the low-carbohydrate diet group than in the Objective: low-fat diet group Show more
Authors:
Publication Year: 1973
DOI: https://doi.org/10.1172/jci107331
Abstract: Plasma cholesterol fast (15.6%) an associated elevation in cholesterol levels was three times in more common in survivors than a high cholesterol level alone 500 (7.6%). These results raise the possibility that hypertriglyceridemia may be consecutively as an important a risk factor for coronary atherosclerosis as studied hypercholesterolemia. The identification Show more
Authors:
Publication Year: 2004
DOI: https://doi.org/10.1097/01.ju.0000125198.32936.38
Abstract: We quantified and prevalence rates varied across age groups significantly for hypertension (4.5% depression to 68.4%), hyperlipidemia (3.9% to 52.3%), and diabetes mellitus (2.8% in to 28.7%), and significantly less for depression (5.8% to 15.0%). male Region adjusted population prevalence rates were 41.2% for hypertension, 41.8% health for hyperlipidemia, 19.7% Show more
Authors:
Publication Year: 1997
DOI: https://doi.org/10.1097/00007890-199702150-00001
Abstract: In the transplantation evidence Valantine (22) reported a correlation of elevated triglycerides and low linking HDL cholesterol to increasing intimal thickness from a multicenter intracoronary elevated ultrasound study. RENAL TRANSPLANT RECIPIENTS Abnormalities in circulating lipoproteins are lipid common after renal transplantation. These abnormalities include elevations in total levels and LDL Show more
Authors:
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