Title: Effect of Herba Epimedii flavone on the osteoblasts metabolism in vitro
Abstract: OBJECTIVE To explore the effect of Herba Epimedii flavone (HEF) on the osteoblast metabolism in vitro. METHOD Osteoblast were obtained from new born rat calvaria by digestive enzymes. MTF, PNPP and RT-PCR were used to observe the proliferation, activity of ALP and mRNA expression of OPG and RANKL of cultured osteoblasts in vitro. RESULT It was found that HEF had the effect on stimulating cell proliferation, activity of ALP and the mRNA expression of OPG of cultured osteoblasts (P < 0.01, P < 0.05). CONCLUSION HEF can promote the proliferation, the differentiation and the expression of OPG mRNA of the osteoblasts cultured in vitro.
Publication Year: 2006
Publication Date: 2006-03-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 4
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