Title: The Clinical Efficacy of Tripterygii Hypoglauci Decremental Therapy in 34 Patients with Corticosteroid Dependent Dermatitis
Abstract: Objective To investigate the clinical efficacy and safety of tripterygii hypoglauci decremental therapy for the treatment of patients with corticosteroid dependent dermatitis. Methods Sixty-eight patients were randomly divided into treatment group and control group. Treatment group( 34 case) : take tripterygii hypoglauci 4 tablets each time,3 times a day,reduce a pill every 2 weeks. Control group( 34 case) : topical 0. 1% hydrocortisone butyrate cream,2 times a day,reduced to once a day after 2 weeks,and cut to every other day after 6 weeks. The patients in both groups received desloratadine tablet 5 mg once a day,and the clinical symptom and sign scores were recorded every 2 weeks until 2 weeks after the courses over. Results Sixtytwo of 68 cases completed the whole course of treatment. The total effective rate of treatment group and control group were 75. 00%,83. 33%,respectively. two groups total effective rate is no statistical differences( P 0. 05). The effect initiating time of treatment group and the control group were( 21. 2 ± 6. 5) d and( 16. 5 ± 5. 1) d,respectively. And with a statistically significant difference between them( P 0. 01). Two weeks after the drug withdrawal,treatment group recurrence rate was 37. 50%,control group recurrence rate was 68. 00%,the recurrence rate of the two groups is statistically difference( P 0. 05). Both groups had no obvious adverse reactions. Conclusion Tripterygii Hypoglauci decremental therapy is safe and effective,and can obviously reduce the recurrence rate in the treatment of corticosteroid dependent dermatitis.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot