Title: Effect of Laparoscopic Surgery and Open Surgical Resection on TNF-α and IL-6 Levels in Patients with Radical Gastrectomy
Abstract: Objective: To investigate Effect of Laparoscopic Surgery and Open Surgical Resection on TNF-α and IL-6 Levels in Patients with Radical Gastrectomy. Methods: 72 patients with radical gastrectomy from March 2011 to May 2013 in our hospital were randomly divided into conventional open surgical group and laparoscopic surgical group,and 36 cases were in each group. The laparoscopic group underwent laparoscopic-assisted laparoscopic radical gastrectomy while the conventional open surgical group was given conventional open gastrectomy. Surgery time,blood loss,anal exhaust time,hospital stay time,preoperative and postoperative serum TNF-α and IL-6 levels were compared between the two groups. Results: The blood loss,anal exhaust time and hospital stay time of the laparoscopic surgical group were significantly less than those of the control group(P0.05); the TNF-α and IL-6 levels of laparoscopic group were significantly lower than those of the conventional open surgical group,the difference was significant(P0.05).Conclusion: The serum TNF-α and IL-6 levels of laparoscopic-assisted radical gastrectomy are lower compared with conventional open surgery postoperativ,and it exerts less impact on immune function,and can reduce the chances of infection,thus it is worth promoting in clinic.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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