Title: Diffusion anisotropy in acute ischemic stroke
Abstract: Objective To evaluate the characteristics of diffusion anisotropy of acute stroke within 24 h from the initial stroke onset. Methods Data of 33 diffusion tensor imaging of 27 patients within 24 h after onset of ischemic were retrospectively analyzed. Fractional anisotropy (FA) and average diffusion coefficient (ADC) were calculated using an off-line computer, while values of FA and ADC were measured in the lesions and contralateral regions. The FA and the ADC values of the lesions were compared with those of the contralateral regions. Results ADC values of the ischemic lesions were significantly lower than those of the contralateral regions (P0.01). There was no significant difference of mean FA values between lesions and the contralateral regions (P=0.74), nor among patients within 6 h, 6-12 h and 12-24 h (P0.05). Significant individual difference was found in changes of mean FA value during acute stage, but not in the occurrence of elevated or unchanged FA among patients within 6 h, 6-12 h and 12-24 h (P=0.73). Conclusion There is no significant difference in diffusion anisotropy between lesions and the contralateral regions within 24 h, whereas individual difference is significant. Individual difference of diffusion anisotropy of acute stroke within 24 h may be helpful to the choice of individual therapeutic schemes of stroke.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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