Title: Clinical Analysis of TS-1 in Treatment of Elderly Patients with Gastric Cancer
Abstract: Objective:To explore and statistical analysis clinical effects,adverse effects and patient satisfactions in the treatment of elderly patients with gastric cancer by TS-1.Method:96 patients with elderly gastric cancer were randomly divided into two groups.The treatment group were treated with TS-1,the control group were treated with oxaliplatin combined with calcium folinate and fluorouracil.Result:The total effective rate of treatment group and control group were 87.5% and 72.9%,with a statistically significant difference(P 0.05);the adverse reactions in the two groups mainly reflected in hepatic injury,myelosuppression and gastrointestinal infection.Compared to 13 cases(27.1%)in the control group,there were 7 cases(14.5%) appeared Ⅲ-IV grade side effects in the treatment group,which had a significant difference(P 0.05).The satisfaction of treatment group and control group were 66.7% and 56.3% respectively,the treatment satisfaction statistics showed that there were no significant difference( P 0.05).Conclusion:TS-1 has a significant efficacy and few adverse effect for the treatment of elderly patients with gastric cancer,which is worth applying in the clinical.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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