Title: Biologic characters of tumor and gastric cancer prognosis
Abstract: [Objective] By studying the clinical data of 338 patients with early gastric cancer(EGC),who had been performed radical resection upon.The lymph node metastasis rules and distribution were analyzed to find out the relationship between lymph node metastasis and clinical pathological specificity,the prognostic factors for the purpose of improving suvival of EGC patients and quality of life,in order to guide the surgical treatment of clinical standardization.[Methods] To review clinical data of the 338 patients and analyze the possible relationship of lymphnode metastasis,the size of tumor,types of histopathology,depth of infiltration,gross classification.Kaplan-Meier method was used to process suvival rate.[Results](1) One hundred and thirty-nine patients(41.1%) had D1 radical lymphatic node dissection,183 patients(54.1%) had D2radical lymphatic node dissection,and other 16 (4.7%) had D3 radical lymphatic node dissection.It was found that lymph node metastasis was affected by the size of tumor and depth of infiltration(P0.05).(2) General 5-year survival rate in a ll of the patients was 92.1%,5-year survival rate in the patients with intramucosa tumor was 97.1% and 5-year survival rate in the patients with submucosa tumor was 85.7%.The survival rate of EGC was related with invasion depth and lymph node metastasis(P=0.043 and 0.004).[Conclusion] By estimating depth of infiltration,the size of tumor and the state of lymph node metastasis,right surgical protocol could be decided in order to improve survival rate and prognosis.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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