Title: Clinical effect of acute paraquat poisoning treatment with xuebijing injection combined with hemoperfusion
Abstract: Objective To analyze the clinical effect of acute paraquat poisoning treatment with Xuebijing injection combined with hemoperfusion.Methods57 patients with acute severe paraquat poisoning from June 2007 to June 2010 in our hospital were included in the study.They were divided into perfusion group and combined treatment group according to treatment.Blood perfusion was used in the perfusion group on the basis of conventional application of first aid treatment of acute paraquat poisoning.Xuebijing injection combined with hemoperfusion were used in the combined treatment group.ResultsIn two groups,especially in combined treatment group,serum ALT,AST,CK,CKMB,LDH,Cr levels and serum CRP,MDA,TNF-α levels decreased,and serum SOD activity increased significantly after treament.In perfusion group,16 cases died and 12 cases were cured.In combined treatment group,9 cases died and 20 cases were cured.The mortality of two groups had significant difference(=3.944,P=0.047).ConclusionXuebijing injection combined with hemoperfusion can reduce the damage of important organs,lower inflammatory factors levels and improve the cure rate of acute paraquat poisoning.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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Cited By Count: 1
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