Title: Plasma cystatin C with chronic renal failure in clinical application
Abstract: Objective Determine the cystatin C concentration of plasma from patients with chronic renal failure,and investigate its clinical significance.Methods Cystatin C concentration of plasma samples froml5 patients with nephrotic syndrome,20 patients(six of them were choused again after being treated with renal transplantation and the condition had turned better)with chronic renal failure and 15 patients with acute glomerulonephritis and normal plasma creatinine(Cr) were detected with immunoturbidimetric.Furthermore,20 cases from healthy people were taken as the control group.Results Patients with nephrotic syndrome and chronic renal failure,plasma cystatin C was significantly higher than the control(P0.01).Plasma cystatin C concentration was still higher than the control to the 5 patients with chronic renal failure after being treated with renal transplantation although the concentration decreased significantly(P0.01).There was no significant difference(P0.05) between acute nephritis group and the control.Conclusion Cystatin C contribute to the assessment of glomerular filtration function,and plasma cystatin C determine the extent of glomerular damage with kidney disease patients and efficacy testing of value indicators.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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