Title: An antihypertensive effect of Lisinopril and its reverse effect on the left ventricular hypertrophy in essential hypertension
Abstract: Objective: To investigate the antihypertensive effect of Lisinopril and its reverse effect on the left ventricular hypertrophy in essential hypertension (EH). Methods: Thirty-eight EH patients complicated left ventricular hypertrophy (LVH) were given Lisinopril 5~20mg per 12 hours a day for 12 weeks. The blood pressure was recorded by ABPM before and after treatment. Comparison of the ventricle thickness by heart Doppler echocardiogram was made at the same time. Results: After 12- week therapy, the blood pressure was significantly lowered and the left intraventricular septum thickness (LVST), the left ventricular posterior wall thickness (LVPWT) and the left ventricular mass indices (LVMI) were markedly decreased (P0.05). Conclusion: Lisinopril not only decreases hypertension but also reverses the hypertrophial ventricle.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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