Title: The effect of unilateral molarless on spatial memory in learning and memory deficit aged rats
Abstract: Objective To evaluate the effect of unilateral molarless on spatial memory in aged rats with different learning and memory ability. Methods According to the mean of escape latencies (EL) of 20 young rats (YR), memory deficit rats(DR) and memory normal rats(NR) were selected from 40 aged rats by Morris water maze. Then, all the rats were randomly divided into unilateral molars extraction groups (YRE, DRE, NRE) and control groups (YRC, DRC, NRC). Two months later, all rats underwent Morris water maze behavior testing. Results Compared with the control group, DRE showed significantly longer EL(P 0.01 ). The percentage of swim distance in platform quadrant of DRE was no different from that in other quadrants , but in the groups of DRC, YR and NR, it was higher significantly (P0.01, P0.05). Conclusion Unilateral molarless may enhance the impairment of learning and spatial memory in DR.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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