Title: Clinical observation of Tangwei capsule combined with Metformin in treatment of patients with Type 2 Diabetes Mellitus
Abstract: Objective To observe the clinical effect of Tangwei capsule combined with metformin in treatment of patients with type 2 diabetes mellitus(T2DM).Methods 110 patients with T2DM were randomly divided into two groups.50 patients were allocated into control group with metformin treatment,while 60 patients were allocated into treatment group with Tangwei capsule combined with metformin treatment.Two groups were treated for three months which is a course of treatment and the clinical effect was compared.The plasma levels of fast blood glucose(FPG),blood glucose of post-meal 2 hours(2 h PG),glycosylated hemoglobin(HbAlc),triglyceride(TG),body mass index(BMI),and hemorheology index which include whole blood viscosity,plasma viscosity,platelet adhesion rate and low-density lipoprotein have been observed.Results The total effective rate in treatment group(88.34%) was higher than that in control group(72.00%,P0.05).FPG,2 h PG,HbA1c and TG after treatment were more significantly decreased as compared with those pre-treatment in two groups(P0.05);and compared with control group,treatment group has better clinical effect(P0.05).Whole blood viscosity,plasma viscosity,platelet adhesion rate and low-density lipoprotein decreased more significantly after treatment as compared with pre-treatment(P0.05);and compared with control group,treatment group has better clinical effect(P0.05).Conclusion There is significant clinical effect in improving blood glucose and blood lipids for the treatment protocols of Tangwei capsule combined with metformin in treatment of patients with T2DM,and it is more secure.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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