Title: Influence of Shenmai injection on surem TNF-α and IL-12 level and cardiac function in chronic heart failure
Abstract: Objective: To explore the clinical effect of Shenmai injection on chronic heart failure and the influence on surem TNF-α and IL-12 level.Methods:A total of 126 cases with chronic heart failure were randomly divided into control group and experimental group.Sixty cases of control group were given routine treatment and 66 patients of experience group received Shenmai injection based on routine treatment for 14 days.Clinical effect,heart function indexes and surem TNF-α and IL-12 level were compared between two groups.Results:The effective rates in experimental group was significantly higher than that in control group(71.2% vs.48.4%,P0.05);after treatment EF% and △D% in experimental group were superior to control group(P0.05);Comparison with control group,surem TNF-α and IL-12 level after treatment were greatly decreased(P0.05).Conclusions: TNF-α and IL-12 play a role in the pathogenesis of chronic heart failure.Shenmai injection for chronic heart failure can greatly improve the clinical effect and decrease the surem TNF-α and IL-12 level.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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