Title: Value of ~(18)F-FDG PET using SPM in the preoperative localization of mesial temporal lobe epilepsy
Abstract: Objective To evaluate the value of 18F-FDG PET using statistical parametric mapping SPM in the preoperative localization of mesial temporal lobe epilepsy.Methods Seventeen patients with mesial temporal lobe epilepsy were examined with 18F-FDG PET,all the PET imaging were analyzed by region of interest(ROI)method and SPM analysis method.Twenty healthy controls were chosen as the control group for SPM analysis.Results The rate of accurate determination of the side and accurate localization were 70.6% and 29.4% for the ROI method,the SPM method were 70.6% and 47.1%,there was significant difference of accurate localization rate between the two methods,P0.05.The SPM analysis revealed nine(52.9%)patients with bilateral temporal metabolic abnormality,twelve(70.6%)patients with frontal and parietal cortex abnormality.Conclusions The 18F-FDG PET using SPM is an objective,convenient and effective method for the localization of mesial temporal lobe epilepsy,and may help to find abnormal cerebral metabolism.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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