Title: Study on a HPLC method of determination of nifedipine content
Abstract: AIM: To establish a HPLC method to determine nifedopine the content and uniformity of nifedopine tablet. METHODS: HPLC condition was set as ODS column, flow phase: methanol water (6040), flow rate: 0.8 ml·min -1 , and detection wavelength: 235 nm. RESULTS: The nifedopine linear range was 0.020-0.200 g·L -1 in this method. The average recovery rates were 99.6%, 98.9%, and 100.4% in high, normal and low concentrations, respectively. The corresponding values of RSD were 0.42%, 0.54% and 0.35% (n=5). CONCLUSION: This HPLC method shows a high specificity and sensitivity, and is accurate, simple and rapid in performance.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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