Title: Curative effect of Valsartan and the effect of drug on left ventricular hypertrophy and diastolic function in patients with essential hypertension
Abstract: Objective To observe antihypertensive effect of Valsartan and the effect of drug on left ventricular hypertrophy and diastolic function in patients with essential hypertension.Methods Forty-six patients with 1~2 stage essential hypertension were given Valsartan 80~160 mg/d for twenty-four weeks.Observe the change of blood pressure before and arter treatment.By echocardiography observe the change of left ventricular structure and diastolic function berore and after treatment.Results After treatment with Valsartan.systolic and diastolic pressure of the patients are both lower than basic titer and have obvious difference(P0.05).Left ventricular mass index of patients were significantly decrased(P0.01).Left ventricular diastolic function was obviously improved(P0.01).Conclusion Valsartan was effective in treatment of hypertension.Valsartan can reverse left ventricular hypertrophy and improve left ventricular diastolic function.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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