Title: Advances on small-molecule inhibitors of interfacing with p53-MDM2 protein-protein interactions
Abstract: p53-MDM2 protein-protein interaction is an important target for antitumor drugs.Inhibiting p53-MDM2 interaction is a promising approach for activating p53.A number of drug screening approaches and technologies have been used to identify novel inhibitor of p53-MDM2 interaction.And small-molecule inhibitors research is one of the most promising areas.The advances on small-molecule inhibitors of p53-MDM2 protein interactions at home and abroad in recent years were summarized.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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