Title: Analysis of clinical distribution and drug resistance of infection due to Enterobacter cloacae
Abstract: Objective:To investigate the clinical distribution and antimicrobial resistance of infections caused by Enterobacter cloacae in our hospital for guiding the clinical application of antibiotics reasonably.Methods:Retrospective analysis of the drug resistance situation and specimen distribution was made to the E.cloacae isolated from our hospital in the recent 3 years.Results:Totally 156 strains of E.cloacae were isolated between Jan 2005 and Apr 2008,the percentages of these strains isolated from sputum,and urine were 42.9% and 23.7%.The rate of resistance to cefazolin was the highest,followed by that to amoxicillin with clavulanic and ampicillin.The rate of resistance to third-generation cepholosporins was 42.7%~49.7%.Tne susceptibility test results showed,All E.cloacae isolated had a relatively high resistance toβlactamase,and carbopenem had high antibioltic activity.Conclusion:E.cloacae mainly causes infections of respiratory tract and urinary tract in clinic.E.cloacae is multidrng resistant and severely resistant to third generation cepholosporins.Imipenem remains to be the first choice to treat the severe infection caused by E.cloacae.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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