Title: Clinical distribution and drug resistance of Enterobacter cloacae
Abstract: OBJECTIVE To investigate the clinical distribution and drug resistance of Enterobacter cloacae causing nosocomial infections and provide basis for the clinical application of the antibiotics.METHODS The infection status and drug resistance of 154 E.cloacae from Jan.2010 to Mar.2011were retrospectively analyzed.RESULTS E.cloacae isolates were mainly isolated from the department of diabetics(50.00%),department of tumor(15.58%),and ICU(12.99%).Among various specimens collected,the wound secretions and sputum accounted for 64.29% and 16.23% respectively.E.cloacae has the lowest drug resistance rate to imipenem which was 0,and has relatively low resistance rates to cefepime,levofloxacin,and amikacin,which were 25.32%,31.82% and 36.36%,respectively;the resistance rates of E.cloacae to ampicillin,cephazolin,and minocycline were relatively high,which were 96.10%,92.21% and 78.57%,respectively.The positive rate of AmpC-producing E.cloacae was 46.10%.CONCLUSION Multidrug-resistance of E.cloacae is serious,it is necessary to strengthen the surveillance for drug resistance in order to guide the reasonable use of antibiotics.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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