Title: The value of Ultrasound in establishing rabbit model bearing VX2 liver Tumor
Abstract: Objective To explore feature of two methods by percutaneous ultrasonic guidance and via laparotomic route in establishing rabbit model bearing VX2 liver tumor and to evaluate the application of ultrasound in monitoring the tumor model.Methods Sixteen New Zealand white rabbits were randomly classified into two groups incuding eight rabbits in each group.A piece of tumor tissue was implanted into the liver by laparotomic route in group 1.VX2 tumor cell suspension was injected into the rabbit liver by percutaneous ultrasounic guidance in group 2.Aseries of ultrasound scanning were performed in the experimental rabbits after 1 week.The sizes of hepatic VX2 tumor and complications were compared between the two groups.Results Tumors were successfully implanted into 7 rabbits in group 1 and 6 rabbits in group 2 respectively.There were no apparent differences between the two groups.Compared with group 2,the complications were scare,the establishment of model was easier and the time consuming was less in the group 1.Conclusion The percutaneous ultrasonic guidance to make rabbit model bearing VX2 liver tumor can be a desirable animal model for the research of ultrasonic intervention.The ultrasound examination is a simple and accurate method for evaluating the VX2 tumor.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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