Publication Information

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'https://openalex.org/W1841578830'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'study': [2], 'the': [3, 18, 32, 42, 46, 74, 78, 86, 95, 123, 169, 205, 219, 230, 246, 261, 269], 'changes': [4], 'of': [5, 20, 31, 97, 101, 109, 113, 122, 139, 148, 161, 165, 196, 201, 222, 232, 263, 271, 276], 'nicotinamide': [6], 'adenine': [7], 'dinucleotide': [8], 'phosphate(NADPH)oxidase': [9], 'in': [10, 23, 37, 54, 129, 180, 218], 'rat': [11], 'left': [12, 33, 98, 154, 157, 188, 191, 247], 'ventricular': [13, 99, 130, 155, 189, 192, 248, 265], 'myocardium': [14, 100, 131, 266], 'after': [15, 81, 89, 243], 'myocardial': [16, 244, 253, 280], 'infarction(MI)and': [17], 'mechanism': [19], "apocynin's": [21], 'intervention': [22], 'NADPH': [24, 114, 124, 149, 166, 202, 233, 238, 256, 272], 'oxidase.MethodsMI': [25], 'group': [26, 44, 56, 59, 174, 212], 'was': [27, 226], 'established': [28], 'by': [29, 118, 267], 'ligation': [30], 'anterior': [34], 'descending(LAD)coronary': [35], 'artery': [36, 51], 'some': [38], 'male': [39], 'Sprague': [40], 'Dawley(SD)rats,while': [41], 'sham-operated': [43, 58, 181], 'underwent': [45], 'same': [47], 'procedure': [48], 'without': [49], 'coronary': [50], 'ligation.The': [52], 'rats': [53, 91], 'MI': [55, 173, 209, 223], 'and': [57, 94, 146, 274], 'were': [60, 92, 104, 116, 151], 'then': [61], 'further': [62], 'randomly': [63], 'divided': [64], 'into': [65], 'two': [66], 'subgroups,with': [67], 'one': [68], 'intragastrically': [69], 'receiving': [70], 'apocynin': [71, 211], '15': [72], 'mg/(kg·d)and': [73], 'other': [75, 220], 'saline': [76], 'on': [77], 'second': [79], 'day': [80], 'operation': [82], 'for': [83], '5': [84], 'weeks.On': [85], '6th': [87], 'week': [88], 'operation,the': [90], 'killed': [93], 'samples': [96], 'non-infarcted': [102], 'area': [103], 'taken': [105], 'from': [106], 'them.The': [107], 'concentration': [108, 141, 160, 195], 'superoxide': [110], 'anions(O2-)and': [111], 'activity': [112, 147, 164, 200, 231, 270], 'oxidase': [115, 125, 150, 239, 257, 273], 'measured': [117], 'absorption': [119], 'spectrophotometry,and': [120], 'expression': [121, 145, 275], 'subunit': [126], 'gp91phox': [127, 143, 170, 206, 235, 277], 'mRNA': [128, 144, 171, 207, 236], 'detected': [132], 'with': [133, 142, 210], 'Reverse': [134], 'Transcription-Polymerase': [135], 'Chain': [136], 'Reaction(RT-PCR).The': [137], 'correlations': [138], 'O2': [140], 'respectively': [152], 'calculated.ResultsThe': [153], 'weight(746.86±53.09)mg,the': [156], 'ventricularweight': [158], 'index(2.55±0.34),the': [159], 'O2-[(83200±7582)RLU/mg': [162], 'protein,the': [163, 199], 'oxidase[(4.77±0.46)RLU/mg': [167], 'protein],and': [168, 204], 'expression(0.69±0.06)in': [172], 'increased': [175], 'significantly': [176, 214], 'compared': [177, 215], 'to': [178, 216, 229], 'those': [179, 217], 'group[(418.33±35.75)mg,(1.34±0.19),(50': [182], '300±3416)RLU/mg': [183], 'protein,(3.38±0.35)RLU/mg': [184], 'protein,and(0.46±0.07)respectively](P0.01': [185], 'or': [186], 'P0.05).The': [187], 'weight(561.17±81.29)mg,the': [190], 'weight': [193, 249], 'index(1.91±0.22),the': [194], 'O2-[(53': [197], '300±5517)RLU/mg': [198], 'oxidase[(3.62±0.32)RLU/mg': [203], 'expression(0.49±0.06)in': [208], 'decreased': [213], 'subgroup': [221], 'group(P0.05).The': [224], 'O2-concentration': [225], 'positively': [227], 'correlated': [228], 'oxidase(r=0.76,P0.01)and': [234], 'expression(r=0.82,P0.01).ConclusionThe': [237], 'system': [240], 'is': [241], 'activated': [242], 'infarction,and': [245], 'increases': [250], 'markedly': [251], 'through': [252], 'remodelling.Apocynin,as': [254], 'a': [255], 'inhibitor,could': [258], 'distinctly': [259], 'decrease': [260], 'production': [262], 'O2-in': [264], 'suppressing': [268], 'mRNA,thus': [278], 'inhibiting': [279], 'remodelling.': [281]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2348440302', 'counts_by_year': [], 'updated_date': '2024-12-24T12:40:16.521577', 'created_date': '2016-06-24'}