Title: Expression of PCNA in colorectal carcinoma and its clinical significance
Abstract: Objective To study the expression of proliferative cell nuclear antigen(PCNA) and its clinical signiflcance in colorectal carcinoma.Methods The expression of PCNA was examined by immunohistochemical S-P methods in 54 colorectal carcinoma tissues and 14 lymph nodes with metastases.Results The positive rate of PCNA was 37.0% in colorectal carcinoma,and was 78.6% in lymph nodes with metastases (P0.05). The positive rate of PCNA was 50.0% in colorectal carcinoma tissues with lymph node metastasis,and was 32.5% in those without metastasis(P0.05).Conclusion The expression of PCNA may play a role in the development and matastasis of colorectal carcinoma.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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