Title: The correlation between the expression of EGFR and lymph node metastasis in Esophageal Squamous Cell Carcinoma
Abstract: Objective:To investigate the correlation between the expression of EGFR and lymph node metastasis in Esophageal Squamous Cell Carcinoma(ESCC).Methods:The expression of EGFR in 80 ESCC was measured by immunohistochemistry,and to the relationship between the expression of EGFR and lymph node metastasis in ESCC was analyzed.All data were analyzed by chi-square test,Pearson rank correlation analysis.Results:The positive rate of EGFR in 80 ESCC and 20 normal esophageal tissues were 61.3% and 20.0% respectively.The positive rate of EGFR in ESCC was much higher than in normal esophageal tissues(χ2=10.63,P0.05).The positive rate of EGFR was positively correlated with lymph node metastasis(P 0.05).Conclusions:EGFR was more highly expressed in ESCC than in normal esophageal tissues and was positively correlated with lymph node metastasis.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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