Title: Effect of obesity on bone mass in postmenopausal women: two sides of a coin
Abstract:Objective To investigate the effect of obesity on bone mass in postmenopausal women.Methods Eighty-five postmenopausal women were included. Height, weight, BMI, fasting insulin, 2 hour insulin after g...Objective To investigate the effect of obesity on bone mass in postmenopausal women.Methods Eighty-five postmenopausal women were included. Height, weight, BMI, fasting insulin, 2 hour insulin after glucose challenge, triglyceride(TG), total cholesterol, leptin, bone mineral density(BMD) at lumbar spine and femoral neck were measured.Results The formulae of BMD were as follows: lumbar BMD=1.085-0.022YSM, femoral neck BMD=-0.371+0.633 height+0.011 BMI-0.007YSM-0.053 lnTG. BMI was positively corralated with TG (r=0.244, P=0.027). There was no difference in lumbar BMD between group of BMI23 kg/m~2 and group of BMI≥23 kg/m~2. However, the femoral BMD was higher in group of BMI≥23 kg/m~2 than that in group of BMI23 kg/m~2 (t=3.496, P=0.001). Conclusion Obesity has both positive and negative effects on bone mass in postmenopausal women. The former is related to mechanical stress of body weight, and the latter is related to the level of TG; the net effect is protective.Read More
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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