Title: PiB Doesn't Fib: Noninvasive Detection of Cerebral Amyloid Angiopathy
Abstract: Carbon 11–labeled Pittsburgh Compound B (PiB) has been shown to penetrate to the central nervous system and mark fibrillar deposits of amyloid-beta. Although most studies of PiB have focused on imaging the senile plaques of Alzheimer disease (AD), PiB also binds to the vascular amyloid deposits that define cerebral amyloid angiopathy (CAA). In this study, researchers sought to confirm the ability of PiB-positron emission tomography (PET) imaging to detect CAA in living patients. They compared imaging findings in …
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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