Title: Liver Transplantation in Patients with Portal Vein Thrombosis
Abstract:Portal vein thrombosis (PVT) used to be valued as the absolute contraindication for liver transplantation. In patients listed for liver transplantation, portal vein thrombosis occurs in 4-15%. Authors...Portal vein thrombosis (PVT) used to be valued as the absolute contraindication for liver transplantation. In patients listed for liver transplantation, portal vein thrombosis occurs in 4-15%. Authors assessed data from 740 consecutive liver transplant cases performed at single institution between 1996 and 2009. Mean follow-up waried from 1 day to 6 years. In 437 male and 303 female patients, some 57 (7,7%) had PVT intraoperatively. In this group of transplants there was incidence of 10,5% liver graft dysfunction, 10,5% hepatic artery thrombosis, 19,3% acute rejection and 17,5% biliary complications respectively. The overall incidence of relaparotomy for bleeding was 28%. Average blood transfusion rate was 17,1 (0-425) units of blood, 27,1 (0-132) units of FFP and 2,6 (0-20) of platelets respectively. In-hospital mortality and overall mortality were 15,8% and 31,6%, respectively. Based on our experience we can conclude that PVT is not the contraindication for LTx. LTx in patients with PVT is associated with higher morbidity rate.Read More