Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2253102682', 'doi': 'https://doi.org/10.1182/blood.v74.6.2144.2144', 'title': 'Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor- mediated agonists and stimulation of C3bi receptor expression and adherence', 'display_name': 'Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor- mediated agonists and stimulation of C3bi receptor expression and adherence', 'publication_year': 1989, 'publication_date': '1989-11-01', 'ids': {'openalex': 'https://openalex.org/W2253102682', 'doi': 'https://doi.org/10.1182/blood.v74.6.2144.2144', 'mag': '2253102682', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2553162'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v74.6.2144.2144', 'pdf_url': 'https://ashpublications.org/blood/article-pdf/74/6/2144/602746/2144.pdf', 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://ashpublications.org/blood/article-pdf/74/6/2144/602746/2144.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5035313128', 'display_name': 'Akira Yuo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'A Yuo', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000601603', 'display_name': 'Sho Kitagawa', 'orcid': 'https://orcid.org/0000-0003-2233-6894'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'S Kitagawa', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109569956', 'display_name': 'A Ohsaka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'A Ohsaka', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109473783', 'display_name': 'Masatsugu Ohta', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Ohta', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108167075', 'display_name': 'Ken‐ichi Miyazono', 'orcid': 'https://orcid.org/0000-0002-9354-2604'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'K Miyazono', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074801500', 'display_name': 'Toru H. Okabe', 'orcid': 'https://orcid.org/0000-0002-3405-1952'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'T Okabe', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102836285', 'display_name': 'Akiko Urabe', 'orcid': 'https://orcid.org/0000-0002-2086-4100'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'A Urabe', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100714641', 'display_name': 'Makoto Saito', 'orcid': 'https://orcid.org/0000-0002-1667-9287'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Saito', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5055125079', 'display_name': 'Fumimaro Takaku', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'F Takaku', 'raw_affiliation_strings': ['Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I74801974']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.229, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 199, 'citation_normalized_percentile': {'value': 0.949108, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '74', 'issue': '6', 'first_page': '2144', 'last_page': '2149'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Erythrocyte Function and Pathophysiology', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12620', 'display_name': 'Signaling Pathways in Disease', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/n-formylmethionine-leucyl-phenylalanine', 'display_name': 'N-Formylmethionine leucyl-phenylalanine', 'score': 0.50209785}, {'id': 'https://openalex.org/keywords/ionomycin', 'display_name': 'Ionomycin', 'score': 0.45004284}, {'id': 'https://openalex.org/keywords/receptor-expression', 'display_name': 'Receptor expression', 'score': 0.42641115}], 'concepts': [{'id': 'https://openalex.org/C2777983669', 'wikidata': 'https://www.wikidata.org/wiki/Q223143', 'display_name': 'Granulocyte', 'level': 2, 'score': 0.6697944}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.6460523}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53310096}, {'id': 'https://openalex.org/C2780656570', 'wikidata': 'https://www.wikidata.org/wiki/Q5090627', 'display_name': 'N-Formylmethionine leucyl-phenylalanine', 'level': 4, 'score': 0.50209785}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.48364007}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.47001126}, {'id': 'https://openalex.org/C2776989580', 'wikidata': 'https://www.wikidata.org/wiki/Q421320', 'display_name': 'Ionomycin', 'level': 3, 'score': 0.45004284}, {'id': 'https://openalex.org/C14942488', 'wikidata': 'https://www.wikidata.org/wiki/Q14908143', 'display_name': 'Granulocyte colony-stimulating factor receptor', 'level': 4, 'score': 0.42699534}, {'id': 'https://openalex.org/C2993002077', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Receptor expression', 'level': 3, 'score': 0.42641115}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.41432944}, {'id': 'https://openalex.org/C2777767877', 'wikidata': 'https://www.wikidata.org/wiki/Q419327', 'display_name': 'Granulocyte colony-stimulating factor', 'level': 3, 'score': 0.39055982}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.34441566}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33760846}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.32923186}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18587214}, {'id': 'https://openalex.org/C54166955', 'wikidata': 'https://www.wikidata.org/wiki/Q658145', 'display_name': 'Chemotaxis', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v74.6.2144.2144', 'pdf_url': 'https://ashpublications.org/blood/article-pdf/74/6/2144/602746/2144.pdf', 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/blood.v74.6.2144.2144', 'pdf_url': 'https://ashpublications.org/blood/article-pdf/74/6/2144/602746/2144.pdf', 'source': {'id': 'https://openalex.org/S200071133', 'display_name': 'Blood', 'issn_l': '0006-4971', 'issn': ['0006-4971', '1528-0020'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W148478075', 'https://openalex.org/W1491767042', 'https://openalex.org/W1537772708', 'https://openalex.org/W1543316318', 'https://openalex.org/W1546078475', 'https://openalex.org/W1578600431', 'https://openalex.org/W1589859267', 'https://openalex.org/W1590061771', 'https://openalex.org/W1591075661', 'https://openalex.org/W1592428766', 'https://openalex.org/W1601467148', 'https://openalex.org/W1675276494', 'https://openalex.org/W1869332987', 'https://openalex.org/W1893019068', 'https://openalex.org/W1965540204', 'https://openalex.org/W1987951694', 'https://openalex.org/W2000423770', 'https://openalex.org/W2046428819', 'https://openalex.org/W2047822138', 'https://openalex.org/W2056225363', 'https://openalex.org/W2057459391', 'https://openalex.org/W2058871035', 'https://openalex.org/W2059365438', 'https://openalex.org/W2061606516', 'https://openalex.org/W2066326340', 'https://openalex.org/W2077299636', 'https://openalex.org/W2091021678', 'https://openalex.org/W2092368843', 'https://openalex.org/W2166281746', 'https://openalex.org/W2328047889', 'https://openalex.org/W2413146963', 'https://openalex.org/W268390163', 'https://openalex.org/W339532153'], 'related_works': ['https://openalex.org/W2169225653', 'https://openalex.org/W2064416809', 'https://openalex.org/W2063619316', 'https://openalex.org/W2059680490', 'https://openalex.org/W2056923695', 'https://openalex.org/W2054992011', 'https://openalex.org/W2034768996', 'https://openalex.org/W2034583712', 'https://openalex.org/W1984619393', 'https://openalex.org/W1965540204'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2253102682', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-19T12:51:26.045131', 'created_date': '2016-06-24'}