Title: ATIIFLAMMATORY ACTIVITY OF SIDA CORDIFOLIA LI SEEDS EXTRACT
Abstract: Summary The seed oil obtained from sida cordiofolia seeds was found to possess anti2inflammatory activity against carrageenan induced paw edema in albino rats. The acute toxicity studies upto a dose level of 2000mg/kg body weight of the rats showed the signs of toxicity like tremors and convulsions. After determination of acute toxicity study up to a therapeutic dose of 400 mg/kg body weight of petroleum ether extract of seeds of sida cordiofolia was found to possess anti2 inflammatory activity against carrageenan induced paw edema in albino rats. The inflammation in carrageenan induced rat paw edema was reduced to 1.10 (p< 0.05) at 30 minute, 1.00 (p< 0.01) at 60 minute, 0.650 (p< 0.01) at 180 minute and 0.375 (p< 0.01). After comparing with control group and standard drug diclofenac sodium the value of seed extract was significant.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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