Publication Information

{'id': 'https://openalex.org/W2168291682', 'doi': 'https://doi.org/10.7326/m13-2981', 'title': 'Evidence Supporting a Systolic Blood Pressure Goal of Less Than 150 mm Hg in Patients Aged 60 Years or Older: The Minority View', 'display_name': 'Evidence Supporting a Systolic Blood Pressure Goal of Less Than 150 mm Hg in Patients Aged 60 Years or Older: The Minority View', 'publication_year': 2014, 'publication_date': '2014-01-14', 'ids': {'openalex': 'https://openalex.org/W2168291682', 'doi': 'https://doi.org/10.7326/m13-2981', 'mag': '2168291682', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24424788'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/m13-2981', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5059580482', 'display_name': 'Jackson T. Wright', 'orcid': 'https://orcid.org/0000-0003-2557-7239'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jackson T. Wright', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112819022', 'display_name': 'Lawrence J. Fine', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lawrence J. Fine', 'raw_affiliation_strings': [' National Institutes of Health'], 'affiliations': [{'raw_affiliation_string': ' National Institutes of Health', 'institution_ids': ['https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053969407', 'display_name': 'Daniel T. Lackland', 'orcid': 'https://orcid.org/0000-0001-5733-6283'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Daniel T. Lackland', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061670923', 'display_name': 'Gbenga Ogedegbe', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Gbenga Ogedegbe', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047520881', 'display_name': 'Cheryl Dennison Himmelfarb', 'orcid': 'https://orcid.org/0000-0003-1918-4316'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Cheryl R. Dennison Himmelfarb', 'raw_affiliation_strings': ['Johns Hopkins University'], 'affiliations': [{'raw_affiliation_string': 'Johns Hopkins University', 'institution_ids': ['https://openalex.org/I145311948']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 47.055, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 314, 'citation_normalized_percentile': {'value': 0.999958, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '160', 'issue': '7', 'first_page': '499', 'last_page': '499'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11950', 'display_name': 'Cardiovascular Syncope and Autonomic Disorders', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11700', 'display_name': 'Hemodynamic Monitoring and Therapy', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.89075685}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.6987759}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4350922}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.40601808}, {'id': 'https://openalex.org/C74909509', 'wikidata': 'https://www.wikidata.org/wiki/Q10387', 'display_name': 'Gerontology', 'level': 1, 'score': 0.40022525}, {'id': 'https://openalex.org/C1862650', 'wikidata': 'https://www.wikidata.org/wiki/Q186005', 'display_name': 'Physical therapy', 'level': 1, 'score': 0.3473192}], 'mesh': [{'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D017410', 'descriptor_name': 'Practice Guidelines as Topic', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D002318', 'descriptor_name': 'Cardiovascular Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017410', 'descriptor_name': 'Practice Guidelines as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/m13-2981', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24424788', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 22, 'referenced_works': ['https://openalex.org/W114929610', 'https://openalex.org/W162468581', 'https://openalex.org/W1971732155', 'https://openalex.org/W1972668441', 'https://openalex.org/W1980967898', 'https://openalex.org/W2023193864', 'https://openalex.org/W2024956494', 'https://openalex.org/W2075662010', 'https://openalex.org/W2097457623', 'https://openalex.org/W2103881469', 'https://openalex.org/W2119340816', 'https://openalex.org/W2126125759', 'https://openalex.org/W2127422554', 'https://openalex.org/W2133416234', 'https://openalex.org/W2155113775', 'https://openalex.org/W2156121263', 'https://openalex.org/W2164487516', 'https://openalex.org/W2168536722', 'https://openalex.org/W2196328866', 'https://openalex.org/W2586133222', 'https://openalex.org/W2908737464', 'https://openalex.org/W75245760'], 'related_works': ['https://openalex.org/W4387497383', 'https://openalex.org/W3183948672', 'https://openalex.org/W3173606202', 'https://openalex.org/W3110381201', 'https://openalex.org/W2948807893', 'https://openalex.org/W2935909890', 'https://openalex.org/W2778153218', 'https://openalex.org/W2758277628', 'https://openalex.org/W1966504330', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'Special': [0], 'Articles1': [1], 'April': [2, 3649, 3659], '2014Evidence': [3], 'Supporting': [4], 'a': [5, 371, 380, 384, 406, 556, 571, 749, 943, 1002, 1328, 1523, 1564, 1578, 1613, 1623, 1933, 1943, 2033, 2059, 2107, 2259, 2513, 2569, 2826, 2980, 3456, 3533, 3619, 3759, 4252, 4257, 4322, 4358], 'Systolic': [6, 1462, 1477, 1633, 3307, 3406], 'Blood': [7, 68, 120, 171, 223, 278, 336, 1463, 1634, 2662, 2675, 2693, 2727, 3559, 3705, 3903, 3958, 3979, 4062, 4339, 4363], 'Pressure': [8, 337, 1464, 1635, 2728, 3560, 3706, 4244, 4340, 4345], 'Goal': [9], 'of': [10, 74, 84, 95, 126, 136, 147, 177, 187, 198, 229, 239, 250, 284, 294, 305, 334, 374, 389, 408, 413, 456, 486, 494, 508, 511, 532, 550, 555, 567, 591, 655, 704, 730, 751, 798, 827, 850, 945, 967, 993, 1019, 1113, 1147, 1154, 1209, 1214, 1220, 1228, 1236, 1304, 1330, 1334, 1362, 1390, 1446, 1526, 1608, 1639, 1646, 1667, 1754, 1769, 1771, 1775, 1845, 1848, 1852, 1864, 1866, 1871, 1877, 1882, 1892, 1946, 1959, 2025, 2053, 2073, 2097, 2102, 2109, 2127, 2171, 2188, 2197, 2261, 2275, 2288, 2297, 2328, 2343, 2349, 2361, 2420, 2449, 2456, 2488, 2554, 2591, 2622, 2635, 2641, 2673, 2680, 2691, 2725, 2762, 2806, 2864, 2873, 2876, 2880, 2884, 2888, 2934, 2982, 2986, 3003, 3015, 3019, 3022, 3028, 3059, 3070, 3076, 3137, 3190, 3265, 3270, 3274, 3290, 3305, 3342, 3348, 3366, 3415, 3520, 3535, 3567, 3572, 3587, 3612, 3621, 3663, 3666, 3703, 3761, 3781, 3789, 3853, 3909, 3919, 3930, 3942, 3952, 3964, 3982, 3990, 4030, 4050, 4066, 4084, 4103, 4124, 4150, 4162, 4174, 4193, 4218, 4307, 4335, 4338, 4393], 'Less': [11], 'Than': [12, 777, 1199], '150': [13, 431, 630, 948, 1337, 2300, 2333, 2557, 3679, 3721], 'mm': [14, 432, 490, 534, 631, 659, 734, 755, 792, 829, 918, 922, 949, 995, 1129, 1222, 1271, 1315, 1338, 1364, 1372, 1407, 1429, 1610, 1620, 1779, 1856, 1873, 1896, 1900, 1963, 1997, 2006, 2017, 2066, 2111, 2157, 2190, 2292, 2301, 2334, 2365, 2453, 2558, 2595], 'Hg': [15, 433, 535, 632, 660, 793, 830, 919, 950, 996, 1223, 1272, 1316, 1339, 1365, 1373, 1408, 1611, 1621, 1857, 1874, 1897, 1901, 1964, 1998, 2018, 2067, 2112, 2191, 2293, 2335, 2366, 2454, 2559, 2596], 'in': [16, 434, 538, 570, 633, 661, 683, 695, 737, 758, 805, 852, 931, 956, 972, 1058, 1074, 1240, 1251, 1286, 1297, 1322, 1345, 1354, 1374, 1384, 1415, 1438, 1449, 1453, 1465, 1474, 1552, 1563, 1582, 1591, 1602, 1681, 1726, 1743, 1757, 1790, 1813, 1820, 1837, 1858, 1902, 1939, 1942, 1987, 2029, 2039, 2056, 2078, 2113, 2115, 2192, 2238, 2242, 2417, 2477, 2481, 2503, 2517, 2606, 2729, 2823, 2937, 2977, 2997, 3061, 3098, 3184, 3224, 3230, 3296, 3309, 3344, 3376, 3403, 3419, 3423, 3461, 3491, 3526, 3628, 3657, 3707, 3723, 3746, 3833, 3836, 3851, 3937, 4256, 4265, 4271, 4275, 4321, 4402], 'Patients': [17, 1195, 1353, 1745], 'Aged': [18, 780, 1746], '60': [19, 437, 541, 636, 665, 670, 686, 781, 811, 910, 1026, 1088, 1100, 1155, 1168, 1200, 1229, 1245, 1282, 1289, 1442, 1650, 1747, 2371, 2376, 2402, 2485, 3684, 3726], 'Years': [20, 782, 1748], 'or': [21, 439, 445, 536, 543, 612, 638, 672, 676, 688, 763, 783, 794, 813, 831, 912, 997, 1121, 1135, 1212, 1238, 1291, 1350, 1683, 1716, 1733, 1749, 1797, 1875, 2063, 2409, 2566, 3350, 3728, 3733, 3960, 4208], 'Older:': [22], 'The': [23, 327, 365, 492, 583, 979, 1090, 1256, 1444, 1498, 1781, 2411, 2677, 3450, 3565, 3934, 3969], 'Minority': [24], 'ViewFREEJackson': [25], 'T.': [26, 37, 53, 158, 3217, 3867, 3877, 4003], 'Wright': [27, 54, 3208, 3691, 4004], 'Jr.,': [28, 55, 4005], 'MD,': [29, 34, 42, 56, 108, 210, 3869, 3874, 3882, 4006], 'PhD,': [30, 50, 265, 3889, 4007], 'Lawrence': [31, 105, 3871], 'J.': [32, 106, 3872], 'Fine,': [33, 107, 3873, 4140, 4156, 4168, 4184, 4199, 4223], 'DrPH,': [35, 39], 'Daniel': [36, 157, 3876], 'Lackland,': [38, 159, 3878, 4142, 4158, 4170, 4186, 4201], 'Gbenga': [40, 208, 3880], 'Ogedegbe,': [41, 209, 3881, 4144, 4188, 4203], 'MPH,': [43, 211, 3883], 'MS,': [44], 'and': [45, 67, 90, 119, 142, 170, 193, 222, 245, 260, 277, 300, 316, 458, 467, 506, 521, 553, 614, 642, 667, 714, 775, 787, 838, 864, 893, 905, 920, 926, 961, 1016, 1035, 1042, 1085, 1095, 1123, 1197, 1313, 1378, 1395, 1470, 1501, 1507, 1517, 1529, 1599, 1669, 1739, 1759, 1765, 1828, 1841, 1917, 1999, 2047, 2075, 2088, 2105, 2137, 2166, 2177, 2206, 2380, 2471, 2500, 2625, 2631, 2637, 2661, 2671, 2689, 2800, 2808, 2811, 2816, 2883, 2928, 2943, 2950, 3025, 3072, 3104, 3128, 3133, 3154, 3163, 3188, 3220, 3228, 3571, 3692, 3863, 3902, 3925, 3945, 3957, 3966, 3978, 4032, 4055, 4061, 4135, 4148, 4216, 4248, 4284, 4362, 4365, 4371, 4398], 'Cheryl': [46, 261, 3885], 'R.': [47, 262, 3886], 'Dennison': [48, 263, 3887, 4118, 4146, 4160, 4190, 4205, 4214, 4225], 'Himmelfarb,': [49, 264, 3888], 'RN,': [51, 266, 3890], 'ANPJackson': [52], 'PhDFrom': [57], 'Case': [58, 110, 161, 213, 268, 3893, 4010, 4036], 'Western': [59, 111, 162, 214, 269, 3894], 'Reserve': [60, 112, 163, 215, 270, 3895], 'University,': [61, 113, 164, 216, 271, 3896], 'Cleveland,': [62, 114, 165, 217, 272, 3897, 4019, 4045], 'Ohio;': [63, 115, 166, 218, 273, 3898], 'National': [64, 116, 167, 219, 274, 350, 1040, 1048, 2658, 2665, 2683, 2741, 2772, 2924, 2946, 3102, 3116, 3899, 3954, 3975, 4058, 4064, 4282, 4359], 'Heart,': [65, 117, 168, 220, 275, 2659, 3900, 3955, 3976, 4059, 4360], 'Lung,': [66, 118, 169, 221, 276, 2660, 3901, 3956, 3977, 4060, 4361], 'Institute,': [69, 121, 172, 224, 279, 3904, 3980, 4063], 'Bethesda,': [70, 122, 173, 225, 280, 3905, 4078], 'Maryland;': [71, 123, 174, 226, 281, 3906], 'Medical': [72, 124, 175, 227, 282, 3907, 4011, 4037, 4082], 'University': [73, 82, 93, 125, 134, 145, 176, 185, 196, 228, 237, 248, 283, 292, 303, 3908, 3917, 3928, 4008, 4034, 4083, 4101, 4122], 'South': [75, 78, 127, 130, 178, 181, 230, 233, 285, 288, 3910, 3913, 4085], 'Carolina,': [76, 128, 179, 231, 286, 3911, 4086], 'Charleston,': [77, 129, 180, 232, 287, 3912, 4090], 'Carolina;': [79, 131, 182, 234, 289, 3914], 'New': [80, 86, 88, 132, 138, 140, 183, 189, 191, 235, 241, 243, 290, 296, 298, 3915, 3921, 3923, 4099, 4114], 'York': [81, 133, 184, 236, 291, 3916, 4100], 'School': [83, 94, 135, 146, 186, 197, 238, 249, 293, 304, 3918, 3929, 4102, 4123], 'Medicine,': [85, 137, 188, 240, 295, 3668, 3920, 4104], 'York,': [87, 139, 190, 242, 297, 3922, 4115], 'York;': [89, 141, 192, 244, 299, 3924], 'Johns': [91, 143, 194, 246, 301, 3926, 4120], 'Hopkins': [92, 144, 195, 247, 302, 3927, 4121], 'Nursing,': [96, 148, 199, 251, 306, 2802, 3931, 4125], 'Baltimore,': [97, 149, 200, 252, 307, 3932, 4130], 'Maryland.Search': [98, 150, 201, 253, 308], 'for': [99, 151, 202, 254, 309, 331, 392, 497, 577, 651, 772, 834, 985, 1023, 1067, 1082, 1093, 1160, 1189, 1194, 1278, 1423, 1550, 1664, 1707, 1984, 2068, 2134, 2143, 2163, 2203, 2212, 2367, 2398, 2469, 2511, 2544, 2560, 2584, 2597, 2722, 2861, 2870, 2926, 2948, 3010, 3056, 3118, 3125, 3143, 3160, 3413, 3624, 3700, 3987, 4095, 4177, 4368], 'more': [100, 152, 203, 255, 310, 724, 1508], 'papers': [101, 153, 204, 256, 311], 'by': [102, 154, 205, 257, 312, 379, 387, 1483, 1912, 1920, 2035, 2465, 2497, 3066, 3151, 3292, 3767, 3819], 'this': [103, 155, 206, 258, 313, 414, 462, 853, 932, 973, 1248, 1682, 1722, 1786, 3938], 'author,': [104, 156, 207, 259], 'DrPHFrom': [109, 160], 'MSFrom': [212], 'ANPFrom': [267], 'authorAuthor,': [314], 'Article,': [315, 3862], 'Disclosure': [317, 3864], 'Informationhttps://doi.org/10.7326/M13-2981': [318], 'SectionsAboutVisual': [319], 'AbstractPDF': [320], 'ToolsAdd': [321], 'to': [322, 346, 420, 430, 482, 502, 527, 589, 629, 790, 857, 877, 899, 1027, 1104, 1127, 1157, 1169, 1206, 1247, 1273, 1307, 1382, 1404, 1459, 1485, 1570, 1605, 1643, 2119, 2132, 2141, 2160, 2175, 2181, 2201, 2210, 2249, 2265, 2285, 2290, 2299, 2309, 2356, 2440, 2530, 2573, 2737, 3197, 3370, 3582, 3616, 3641, 3710, 3720, 3741, 3758, 3774, 3838, 4318, 4351, 4355, 4374], 'favoritesDownload': [323], 'CitationsTrack': [324], 'CitationsPermissions': [325], 'ShareFacebookTwitterLinkedInRedditEmail': [326], '“2014': [328], 'Evidence-Based': [329, 2720, 3698], 'Guideline': [330, 2721, 3261], 'the': [332, 342, 347, 359, 409, 418, 422, 454, 471, 476, 479, 484, 514, 519, 524, 529, 551, 560, 565, 592, 620, 624, 645, 648, 679, 692, 702, 708, 718, 727, 799, 806, 820, 824, 848, 866, 936, 957, 968, 1061, 1137, 1145, 1183, 1293, 1298, 1323, 1355, 1375, 1388, 1391, 1396, 1419, 1433, 1471, 1487, 1518, 1537, 1553, 1640, 1691, 1703, 1751, 1760, 1772, 1829, 1838, 1846, 1878, 1929, 1956, 2023, 2085, 2098, 2150, 2153, 2185, 2219, 2234, 2243, 2267, 2271, 2286, 2295, 2347, 2352, 2388, 2396, 2414, 2418, 2424, 2428, 2432, 2442, 2460, 2467, 2474, 2489, 2493, 2498, 2501, 2509, 2527, 2532, 2575, 2615, 2619, 2626, 2632, 2638, 2681, 2695, 2723, 2733, 2738, 2821, 2829, 2862, 2867, 2871, 2877, 2885, 2978, 2983, 3000, 3057, 3062, 3067, 3073, 3099, 3138, 3146, 3231, 3263, 3271, 3306, 3310, 3367, 3420, 3497, 3658, 3664, 3696, 3701, 3712, 3777, 3814, 3824, 3943, 3950, 3953, 3961, 3991, 4151, 4163, 4175, 4194, 4266, 4281, 4311, 4366], 'Management': [333, 2724, 3058, 3702], 'High': [335, 1056, 2674, 2692, 2726, 3704], 'In': [338, 701, 1535, 1804, 2095, 2149, 2270, 2537, 3640, 3652], 'Adults:': [339, 2730], 'Report': [340, 2679, 2731, 3269], 'From': [341, 2732, 3892, 4357], 'Panel': [343, 2317, 2734], 'Members': [344, 2735], 'Appointed': [345, 2736], 'Eighth': [348, 2739], 'Joint': [349, 2664, 2682, 2740], 'Committee': [351, 2666, 2684, 2742], '(JNC': [352, 2743], '8)”': [353], 'recommends': [354, 823], 'several': [355], 'major': [356, 465, 1413, 2069, 3578], 'changes': [357], 'from': [358, 428, 627, 874, 889, 897, 1033, 1697, 2084, 2445, 2610, 2828, 3718, 4280], 'JNC': [360, 2696], '7': [361, 2697], 'report': [362, 2981], '(1,': [363], '2).': [364, 1497, 1557], '2014': [366, 821, 1202, 2719, 3650, 3661, 3697], 'guideline': [367, 393, 472, 498, 742, 822, 1203, 1257, 1434, 1692, 2254], 'is': [368, 547, 1102, 1232, 1437, 1656, 1713, 2246, 2306, 3817, 4328], 'based': [369], 'on': [370, 402, 1107, 1144, 1340, 2395, 2667, 2685, 2798, 2804, 2813, 2918, 2975, 2991, 3169, 3262, 3280, 3523, 3577, 4234, 4396], 'systematic': [372], 'review': [373, 723], 'randomized,': [375], 'controlled': [376, 1126, 3537], 'trials': [377, 1452, 1493, 1642, 1971, 1988, 2041], '(RCTs)': [378], 'multidisciplinary': [381, 4319], 'panel': [382, 410, 719, 1204, 2255, 2353, 2389, 2433], 'using': [383, 1150, 1216], 'process': [385], 'informed': [386], 'Institute': [388, 493, 2663, 2761, 2925, 2947, 3959, 4364], 'Medicine': [390, 495], 'recommendations': [391, 650], 'development': [394, 499], '(3).': [395, 516], 'Although': [396, 461, 847], 'there': [397, 546], 'was': [398, 640, 1263, 1481, 1561, 1788, 2122, 2256, 2427, 2438, 2568, 4228], 'almost': [399], 'unanimous': [400, 2393], 'agreement': [401], 'nearly': [403, 965, 1921], 'all': [404, 1592, 1665, 1940, 1985], 'recommendations,': [405], 'minority': [407, 480, 525], '(the': [411], 'authors': [412, 3944, 3970], 'commentary)': [415], 'disagreed': [416], 'with': [417, 604, 616, 644, 674, 803, 836, 844, 868, 880, 987, 1224, 1253, 1370, 1612, 1622, 1799, 1817, 1975, 1979, 1989, 2011, 2058, 2092, 2124, 2226, 2258, 2340, 2378, 2386, 2608, 2999, 3145, 3299, 3493, 3528, 3695, 3750, 3787, 4277, 4330], 'recommendation': [419, 496, 2397, 3709], 'increase': [421, 953, 2441, 3711], 'target': [423, 451, 485, 531, 561, 626, 654, 944, 1005, 1333, 1426, 1725, 1774, 1787, 1891, 2360, 2516, 2540, 2589, 3713], 'systolic': [424, 1020, 1801, 3219, 3301, 3373, 3417, 3426, 3714, 3815, 3825, 4397], 'blood': [425, 870, 954, 1021, 1379, 1835, 2001, 2026, 2037, 2103, 2221, 2250, 2514, 2534, 3222, 3374, 3411, 3530, 3568, 3574, 3584, 3614, 3715, 4400], 'pressure': [426, 871, 1022, 2002, 2027, 2104, 2222, 2251, 2515, 2535, 3223, 3375, 3412, 3531, 3569, 3615, 3716, 3772], '(SBP)': [427, 3717], '140': [429, 489, 533, 628, 658, 733, 754, 791, 828, 994, 1128, 1221, 1270, 1312, 1406, 1428, 1778, 1855, 1872, 1962, 1996, 2016, 2065, 2291, 2364, 2452, 2594, 3719, 3744, 3828], 'persons': [435, 539, 634, 662, 759, 802, 1024, 1185, 1242, 1279, 1287, 1346, 1439, 2116, 2399, 2562, 3298, 3724], 'aged': [436, 540, 635, 669, 685, 760, 810, 909, 1025, 1099, 1118, 1167, 1288, 1347, 1730, 1794, 2117, 2563, 3226, 3725], 'years': [438, 542, 637, 666, 671, 687, 762, 812, 843, 911, 1101, 1120, 1156, 1171, 1246, 1283, 1290, 1349, 1368, 1715, 1732, 1796, 1951, 2121, 2377, 2385, 2403, 2565, 2602, 3347, 3727], 'older': [440, 544, 639, 673, 689, 814, 1084, 1122, 1351, 1416, 1440, 1454, 1648, 1717, 1734, 1798, 1948, 2277, 2374, 2400, 2483, 2567, 3297], 'without': [441, 1132, 1412, 2313, 3730], 'diabetes': [442, 3731], 'mellitus': [443, 3732], '(DM)': [444], 'chronic': [446, 3734, 4324], 'kidney': [447, 3735, 4325], 'disease': [448, 579, 1513, 1533, 2146, 2169, 4326], '(CKD).': [449], 'This': [450, 517, 1558, 1826], 'guides': [452], 'both': [453, 1114, 1385], 'initiation': [455], 'therapy': [457, 3522], 'treatment': [459, 569, 1163, 1215, 1357, 1724, 1809, 1974, 2054, 2327, 3295, 3414], 'goals.': [460], 'issue': [463, 3662], 'has': [464, 1409], 'clinical': [466, 617, 1133, 2932, 4408], 'public': [468, 1009], 'health': [469, 1341], 'implications,': [470], 'only': [473, 833, 1521, 1814], 'briefly': [474], 'summarized': [475], 'concerns': [477], 'underlying': [478, 523], 'opinion': [481, 512, 526], 'maintain': [483, 528], 'less': [487, 656, 731, 752, 946, 1161, 1268, 1335, 1678, 1776, 1853, 1893, 1960, 1994, 2003, 2014, 2362, 2450, 2555, 2592, 3742, 3775], 'than': [488, 610, 657, 664, 732, 753, 796, 841, 947, 1087, 1176, 1244, 1269, 1281, 1336, 1441, 1509, 1649, 1690, 1777, 1854, 1894, 1949, 1961, 1995, 2004, 2015, 2294, 2332, 2363, 2370, 2375, 2383, 2401, 2451, 2484, 2556, 2593, 2600, 3743, 3776], 'Hg.': [491, 1780, 2007, 2302], 'encourages': [500], 'guidelines': [501, 1696, 2609], 'provide': [503, 1399, 1767, 1843, 2323], '“a': [504], 'description': [505], 'explanation': [507], 'any': [509, 1274], 'differences': [510, 1073, 1819], 'regarding': [513], 'recommendation”': [515], 'summarizes': [518], 'evidence': [520, 621, 646, 706, 746, 1208, 1235, 1262, 1400, 1421, 1768, 1827, 2050, 2264, 2325, 2342, 2437, 2510, 2528, 2942], 'rationale': [522], 'SBP': [530, 585, 625, 653, 681, 710, 728, 788, 825, 992, 1004, 1125, 1218, 1267, 1276, 1309, 1332, 1361, 1403, 1425, 1489, 1607, 1711, 1773, 1850, 1870, 1890, 1957, 1993, 2013, 2061, 2114, 2154, 2186, 2283, 2304, 2330, 2359, 2425, 2443, 2552, 2590, 3740], 'lower': [537, 832], 'until': [545, 1387], 'greater': [548, 2331], 'certainty': [549], 'risks': [552], 'benefits': [554, 1211], 'higher': [557, 584, 680, 1003, 1174, 1488, 1723, 1834, 2582], 'target.First,': [558], 'increasing': [559, 623, 2423, 2459, 2466, 2512], 'will': [562, 1006, 2336], 'probably': [563], 'reduce': [564, 2310, 2337], 'intensity': [566], 'antihypertensive': [568, 884, 1976, 3293, 3521], 'large': [572, 980, 2236], 'population': [573, 960, 981, 1566], 'at': [574, 594, 982, 990, 1173, 1366, 1661, 1832, 1868, 2522, 2581, 2916, 3167, 3999, 4232], 'high': [575, 983, 3841], 'risk': [576, 607, 984, 1066, 1076, 1091, 1108, 1139, 1175, 1237, 1663, 1983, 2468, 2583, 4272], 'cardiovascular': [578, 596, 1068, 1075, 2070, 2311, 2338, 2479, 3579], '(CVD)': [580], '(Table': [581, 1070, 1317, 1496, 1556], '1).': [582], 'goal': [586, 682, 729, 750, 826, 1219, 1277, 1310, 1712, 1851, 1958, 2305, 2426, 2444, 2461, 2553], 'would': [587, 951, 962, 2541, 2603], 'apply': [588], 'some': [590, 1484, 3747, 3834, 3852], 'groups': [593, 743, 1386, 1824, 2031], 'highest': [595, 1662], 'risk,': [597, 1149], 'such': [598, 1652], 'as': [599, 1586, 1588, 1653, 2524, 2526], 'African': [600, 1096, 1654, 1658], 'Americans,': [601, 1655], 'hypertensive': [602, 907, 959, 970, 1728, 2278, 3378, 3463], 'patients': [603, 971, 1083, 1603, 1647, 1729, 1793, 1904, 1947, 2057, 2279, 2368, 2579, 2598, 3345, 3379, 3492, 3749, 4276], 'multiple': [605], 'CVD': [606, 1134, 2470, 2504], 'factors': [608], 'other': [609, 1275, 1644, 1684, 1698], 'DM': [611, 675, 837, 2408], 'CKD,': [613], 'those': [615, 668, 835, 839, 1177, 1252, 2373, 2381, 3941], 'CVD.': [618], 'Second,': [619], 'supporting': [622, 647], 'insufficient': [641, 2439], 'inconsistent': [643], "panel's": [649, 1554], 'an': [652, 991, 1151, 1217, 1225, 1266, 1308, 1331, 1360, 1424, 1606, 1708, 1849, 1869, 1889, 1990, 2012, 2230, 2281, 2329, 2358, 2551], 'younger': [663, 764, 840, 1086, 1184, 1243, 1280, 2369, 2382, 2599], 'CKD.': [677, 2410], 'Third,': [678], 'individuals': [684, 1455], 'may': [690, 2462, 3756, 3830, 3848], 'reverse': [691], 'decades-long': [693], 'decline': [694, 2822], 'CVD,': [696, 986, 1593, 2106], 'especially': [697, 736], 'stroke': [698, 2136, 2164, 2204, 2239, 2824, 3291, 3525], 'mortality': [699, 1344, 2480, 3993], '(4).': [700, 941, 1037], 'absence': [703, 2419], 'definitive': [705, 2262, 2421], 'defining': [707], 'optimum': [709, 2268, 2429], 'target,': [711, 1249, 1490], 'observational': [712], 'studies': [713, 2101], 'RCT': [715, 1234, 1435, 2074, 2263, 2494], 'data': [716, 2495, 3110, 3623, 4279], 'that': [717, 902, 964, 1001, 1259, 1401, 1676, 1702, 1721, 1785, 1888, 2051, 2233, 2320, 2326, 2416, 2436, 2458, 2508, 2550, 2577, 3847], 'did': [720, 859, 1546, 2390, 2548], 'not': [721, 860, 1078, 1547, 2391, 2406, 3947], 'systematically': [722], 'strongly': [725], 'support': [726], 'Hg,': [735, 756, 923, 1130, 1430], 'high-risk': [738, 1685, 2518], 'individuals.': [739], 'Other': [740], 'recent': [741, 1695, 2235, 3494, 3654], 'reviewing': [744], 'similar': [745], 'have': [747, 928, 1124, 1186, 1700, 2280, 2407], 'recommended': [748, 2533, 3779], 'particularly': [757], '80': [761, 1348, 1714, 1731, 2564, 2601, 3346], '(5–9).Table': [765], '1.': [766], 'U.S.': [767, 3141, 3962, 3992], 'Cardiovascular': [768, 2799, 3266, 3983, 4051, 4262], 'Disease': [769, 3126, 3161, 4263, 4369], 'Death': [770], 'Rates': [771, 3132, 4337], 'Persons': [773, 1059, 1166, 2080], 'Younger': [774, 1198], 'Older': [776, 784, 1196, 2079, 4267], '65': [778, 1950], 'yPersons': [779], 'With': [785, 1060, 2081], 'Hypertension': [786, 1191, 1296, 2636, 2642, 2881, 2899, 2904, 2912, 3060, 3071, 3095, 3308, 3407, 4308], 'Controlled': [789], 'LowerMore': [795], 'half': [797, 966], '72': [800], 'million': [801, 3626], 'hypertension': [804, 851, 1306, 1668, 1802, 2875, 2936, 2976, 3191, 3343, 3418, 3427, 3816], 'United': [807, 1030, 2244, 2272, 2616, 3100, 3193, 3232], 'States': [808, 2245, 3194], 'are': [809, 1117, 1172, 1179, 1660, 1670, 2090, 2224, 2580, 3940], '(10,': [815, 886], '11).': [816], 'Among': [817, 4246, 4342, 4347], 'these': [818, 1492, 3854], 'individuals,': [819], '70': [842, 1119, 1795, 2118, 2384], 'CKD': [845], '(2).': [846, 1284], 'prevalence': [849], 'age': [854, 933, 974, 1152, 1226, 3349], 'group': [855, 934, 1358], '(65%': [856], '67%)': [858], 'change': [861], 'between': [862, 1311, 1823], '1999': [863, 3196], '2010,': [865], 'percentage': [867], 'adequate': [869], 'control': [872, 1376, 3189, 4274], 'increased': [873], '27.4%': [875], '(1999–2000)': [876], '50.5%': [878], '(2011–2012),': [879], '82.2%': [881], 'now': [882], 'receiving': [883], 'medications': [885], '12).': [887], 'Data': [888], 'NHANES': [890, 1038, 3130, 3147], '(National': [891], 'Health': [892, 1041, 1049, 2927, 2949, 3103, 3119, 3236, 3965, 4260, 4283], 'Nutrition': [894, 1043, 3105, 4285], 'Examination': [895, 1044, 1050, 3106, 4286], 'Survey)': [896], '2001': [898], '2008': [900], 'show': [901], 'among': [903, 3096, 3192], 'treated': [904, 958, 1604, 2276], 'untreated': [906, 969], 'adults': [908, 3097, 3225, 3627], 'older,': [913, 1292, 1859, 3729], 'median': [914], 'SBPs': [915, 927], 'were': [916, 1494, 1811], '136': [917], '152': [921], 'respectively': [924], '(13),': [925], 'been': [929], 'decreasing': [930, 3768], 'over': [935, 3229], 'past': [937], '5': [938], 'decades': [939], '(Figure)': [940], 'Thus,': [942, 1143, 1418, 1673], 'likely': [952, 2308], 'pressures': [955, 1380, 1836, 2038, 3753, 4401], 'suggest': [963], 'range': [975, 1092, 2287, 2296], 'should': [976, 2520], 'remain': [977], 'untreated.': [978], 'most': [988, 2307], 'currently': [989], 'lower,': [998], 'creates': [999], 'concern': [1000, 2457, 2576], 'adversely': [1007], 'affect': [1008], 'health.Figure.': [1010], 'Smoothed': [1011], 'weighted': [1012], 'frequency': [1013], 'distribution,': [1014], 'median,': [1015], '90th': [1017], 'percentile': [1018], '74': [1028], 'y:': [1029], 'States,': [1031, 2273, 3233], '1959–2010.Reproduced': [1032], 'Lackland': [1034, 2778], 'colleagues': [1036, 3693], '=': [1039, 1047, 1915, 2043, 3798, 3809], 'Survey;': [1045], 'NHES': [1046], 'Survey.': [1051], 'Download': [1052, 1054], 'figure': [1053], 'PowerPoint': [1055], 'Risk': [1057, 1742], 'Higher': [1062], 'GoalAge': [1063], 'substantially': [1064], 'increases': [1065], 'events': [1069, 1807, 2071, 2170, 2312, 2339, 3580], '1),': [1071], 'so': [1072], 'do': [1077, 2405, 3946], 'justify': [1079], 'different': [1080, 3573], 'targets': [1081, 1680, 3490], 'years.': [1089, 1230, 1443, 2486], 'white': [1094], 'American': [1097, 2620, 2627, 2633, 2792, 2830, 2984, 3001, 3005, 3008, 3013, 3017, 3068, 3272], 'men': [1098, 1112], '9%': [1103], '30%,': [1105], 'depending': [1106], 'factor': [1109, 4273], 'profile.': [1110], 'For': [1111], 'ethnicities': [1115], 'who': [1116, 1178, 2404, 4411], 'even': [1131, 1181], 'DM,': [1136, 2379, 2756, 3248], '10-year': [1138], 'exceeds': [1140], '20%': [1141], '(14).': [1142], 'basis': [1146, 2348], 'absolute': [1148], 'threshold': [1153, 1227], 'define': [1158], 'eligibility': [1159], 'aggressive': [1162, 1679], 'lacks': [1164], 'consistency.': [1165], '79': [1170, 1571, 2120], 'younger,': [1180], 'if': [1182], 'DM.Insufficient': [1187], 'Evidence': [1188, 1863, 2077], 'Differential': [1190], 'Treatment': [1192, 1867, 2672, 2690, 3341, 3562], 'Benefit': [1193, 1865], 'YearsThe': [1201], 'failed': [1205], 'identify': [1207], 'differential': [1210, 1710], 'harms': [1213], 'There': [1231], 'little': [1233, 2341], 'benefit': [1239, 1303, 1329, 1411, 1447, 2010, 2052], 'treating': [1241, 1305], 'except': [1250], 'diastolic': [1254, 2000, 3221, 3804, 4399], 'hypertension.': [1255, 3302], 'indicates': [1258], 'no': [1260, 1818, 2049], 'qualifying': [1261], 'found': [1264, 1327, 2009, 2048], 'comparing': [1265], 'However,': [1285, 2546, 3737], 'SHEP': [1294, 1397, 1499, 1839, 2086, 2151, 3314], '(Systolic': [1295], 'Elderly': [1299, 1325, 1466, 1475, 3311, 3404], 'Program)': [1300], 'trial': [1301, 1398, 1479, 1500, 1520, 1544, 1840, 1886, 1931, 2087, 2216, 3369, 3460], 'showed': [1302], '145': [1314, 2298], '2)': [1318], '(15).': [1319], 'HYVET': [1320, 1356, 1394, 1502, 1842, 2089, 2193, 3338], '(Hypertension': [1321], 'Very': [1324], 'Trial)': [1326], 'outcomes,': [1342], 'including': [1343, 2229, 2492], '(16).': [1352], 'achieved': [1359], '144': [1363, 1899], '2': [1367, 1450, 1953], 'compared': [1369, 1978], '159': [1371], 'group,': [1377], 'continued': [1381], 'decrease': [1383, 2502, 2531], 'end': [1389, 1755], 'trial.': [1392, 3500], 'Therefore,': [1393], 'reducing': [1402, 2478], 'around': [1405, 1427], 'substantial': [1410], 'harm': [1414, 2464], 'persons.': [1417], 'best': [1420], 'available': [1422, 2321], 'which': [1431, 1560], 'meets': [1432], 'criteria,': [1436], 'lack': [1445, 2260], 'seen': [1448], 'Japanese': [1451, 1641, 3368], '(JATOS': [1456], '[Japanese': [1457], 'Trial': [1458, 1862], 'Assess': [1460], 'Optimal': [1461], 'Hypertensive': [1467, 1744], 'Patients]': [1468], '[17]': [1469], 'VALISH': [1472, 1519, 1761, 1782], '[Valsartan': [1473], 'Isolated': [1476, 3405], 'Hypertension]': [1478], '[18])': [1480], 'cited': [1482], 'rationalize': [1486], 'but': [1491], 'underpowered': [1495], 'together': [1503], 'reported': [1504, 1577, 1812, 1932], '365': [1505], 'strokes': [1506, 1528, 1911, 1919, 1941, 1986], '285': [1510], 'coronary': [1511, 1531, 1596], 'heart': [1512, 1532, 1597, 1600, 2145, 2168], 'events,': [1514], 'whereas': [1515], 'JATOS': [1516, 1758, 3361], 'had': [1522], 'combined': [1524], 'total': [1525, 1594], '125': [1527, 3799], '67': [1530], 'events.': [1534, 2587], 'addition,': [1536, 1637, 2538], 'much': [1538], 'larger': [1539], 'FEVER': [1540, 1930, 3447], '(Felodipine': [1541], 'Event': [1542, 1741, 3452], 'Reduction)': [1543], '(19)': [1545], 'meet': [1548], 'criteria': [1549], 'inclusion': [1551], 'deliberation': [1555], 'trial,': [1559, 1762, 2152], 'conducted': [1562], 'Chinese': [1565, 3462], '(age': [1567], 'range,': [1568], '50': [1569], 'years;': [1572], 'mean': [1573, 3770], 'age,': [1574, 1906], '62': [1575], 'years),': [1576], 'significant': [1579, 1589], '27%': [1580], 'reduction': [1581, 1938, 2028, 2187, 2237, 2252, 3570], 'its': [1583, 2446], 'primary': [1584, 2935], 'outcome,': [1585], 'well': [1587], 'reductions': [1590], 'mortality,': [1595, 2505], 'disease,': [1598], 'failure': [1601], '137': [1609], 'thiazide': [1614, 1624], 'diuretic–calcium-channel': [1615], 'blocker': [1616], 'combination': [1617], 'versus': [1618, 1898], '143': [1619], 'diuretic': [1625], 'plus': [1626], 'placebo': [1627, 1980], '(19).Table': [1628], '2.': [1629], 'Trials': [1630], 'Comparing': [1631], 'Different': [1632], 'ThresholdsIn': [1636], 'generalizability': [1638], 'populations': [1645, 1686, 2519], 'years,': [1651, 2372], 'uncertain.': [1657], 'Americans': [1659, 2482], 'complications': [1666], 'historically': [1671], 'undertreated.': [1672], 'we': [1674, 2506, 2547], 'believe': [1675, 2549], 'recommending': [1677], 'requires': [1687], 'stronger': [1688], 'justification': [1689], 'cites.': [1693], 'Three': [1694], 'countries': [1699], 'concluded': [1701, 1784, 2507], 'appropriate': [1704], 'cut': [1705], 'point': [1706], 'age-related': [1709], '(5–7).': [1718], 'We': [1719, 2767], 'agree': [1720], 'frail': [1727, 2561], 'better': [1735, 4331], 'reflects': [1736], 'existing': [1737], 'evidence.Safety': [1738], 'Adverse': [1740], 'OlderDespite': [1750], 'limited': [1752], 'number': [1753], 'points': [1756], 'their': [1763, 3653, 3762, 3769], 'size': [1764], 'duration': [1766], 'safety': [1770, 1847], 'investigators': [1783], 'safe': [1789], 'relatively': [1791], 'healthy': [1792], 'isolated': [1800, 3300, 3416, 3425], '(18).': [1803], 'JATOS,': [1805], 'adverse': [1806, 2315], 'requiring': [1808], 'discontinuation': [1810, 1821], '36': [1815], 'patients,': [1816], 'rate': [1822], '(17).': [1825], 'favorable': [1830], 'results': [1831, 2083, 3304, 3365], 'slightly': [1833], 'reassurance': [1844], 'nonfrail': [1860], 'persons.Other': [1861], 'LowerResults': [1876], 'SPS3': [1879, 3486, 3498], '(Secondary': [1880], 'Prevention': [1881, 3289, 4056, 4264, 4372], 'Small': [1883], 'Subcortical': [1884], 'Strokes)': [1885], 'indicated': [1887], '130': [1895], '3020': [1903], '(mean': [1905], '63': [1907], 'years)': [1908], 'reduced': [1909, 1982], 'subsequent': [1910], '19%': [1913], '(P': [1914, 1923, 1935], '0.08)': [1916], 'hemorrhagic': [1918], '50%': [1922], '<': [1924, 1936], '0.01)': [1925], '(20).': [1926], 'Of': [1927], 'note,': [1928], '44%': [1934], '0.001)': [1937], 'subgroup': [1944], 'analysis': [1945, 2231, 3989], '(17).Finally,': [1952], 'meta-analyses': [1954], 'supported': [1955], '(21,': [1965], '22).': [1966], 'A': [1967, 2588, 3064, 3268, 3643, 3672, 4297, 4302, 4315, 4405], 'meta-analysis': [1968, 2021, 3534, 3586, 3620], 'involving': [1969], '16': [1970], 'analyzed': [1972], 'whether': [1973], 'drugs': [1977], 'significantly': [1981], 'average': [1991, 2282], 'baseline': [1992, 2036, 2060, 3583], '90': [2005], 'It': [2008], '(21).': [2019], 'Another': [2020], 'examined': [2022], 'effects': [2024, 3566], 'patient': [2030, 3786], 'defined': [2032], 'priori': [2034], '32': [2040], '(n': [2042], '201': [2044], '566': [2045], 'participants)': [2046], 'differed': [2055], 'below': [2062], 'above': [2064, 3827], '(22).Consistency': [2072], 'Observational': [2076], 'HypertensionThe': [2082], 'consistent': [2091, 2225], 'epidemiologic': [2093, 2100, 2227], 'studies.': [2094, 3631], 'one': [2096, 2539, 3625], 'largest': [2099], 'decrement': [2108, 2155], '20': [2110], 'associated': [2123, 4329], 'hazard': [2125, 2161, 2195], 'ratios': [2126, 2162, 2196], '0.50': [2128], '(95%': [2129], 'CI,': [2130], '0.48': [2131], '0.52)': [2133], 'fatal': [2135], '0.60': [2138], '(CI,': [2139, 2173, 2179, 2199, 2208], '0.58': [2140], '0.61)': [2142], 'ischemic': [2144, 2167], 'death': [2147, 2165, 2205, 2240], '(23).': [2148], '(12': [2156], 'Hg)': [2158], 'corresponded': [2159], '0.71': [2172, 2207], '0.31': [2174], '1.59)': [2176], '0.80': [2178], '0.57': [2180], '1.59),': [2182], 'respectively.': [2183], 'Similarly,': [2184], '15': [2189], 'produced': [2194], '0.61': [2198], '0.38': [2200], '1.00)': [2202], '0.42': [2209], '1.19)': [2211], 'cardiac': [2213], 'death.': [2214], 'These': [2215], 'results,': [2217], 'given': [2218], 'smaller': [2220], 'reductions,': [2223], 'data,': [2228], 'suggesting': [2232], '(50%)': [2241], 'partially': [2247, 2472], 'related': [2248], '(4).SummaryThe': [2253], 'faced': [2257], 'determine': [2266], 'SBP.': [2269], 'millions': [2274], 'closer': [2284], '135': [2289, 4087], 'Which': [2303], 'overwhelming': [2314], 'events?': [2316], 'members': [2318], 'agreed': [2319, 2355], 'RCTs': [2322], 'strong': [2324, 2525], 'serious': [2344, 2586], 'harm.': [2345], 'On': [2346], 'expert': [2350, 2972], 'opinion,': [2351], 'also': [2354, 2604], 'recommend': [2357], 'CKD.However,': [2387], 'reach': [2392], 'consensus': [2394, 2973], 'majority': [2412], 'embraced': [2413], 'view': [2415, 3951], 'evidence,': [2422, 2491], 'approach.': [2430], 'We,': [2431], 'minority,': [2434], 'believed': [2435], 'current': [2447], 'level': [2448], 'because': [2455], 'cause': [2463], 'undoing': [2473], 'remarkable': [2475], 'progress': [2476], 'Because': [2487], 'overall': [2490], 'reviewed': [2496], 'panel,': [2499], 'be': [2521, 2605, 3831, 3849, 3997], 'least': [2523], 'required': [2529], 'target.': [2536], 'simplify': [2542], 'implementation': [2543], 'clinicians.': [2545], 'reasonable': [2570], 'alternate': [2571], 'approach': [2572], 'addressing': [2574], 'elderly': [2578, 3377, 3424, 3748], 'treatment-related': [2585], 'line': [2607], 'Europe': [2611], '(5),': [2612], 'Canada': [2613], '(6),': [2614], 'Kingdom': [2617], '(7),': [2618], 'College': [2621, 2985, 3273], 'Cardiology': [2623, 2889, 2987], 'Foundation': [2624, 2988], 'Heart': [2628, 2793, 2831, 3276], 'Association': [2629, 2794, 3021, 3277], '(8),': [2630], 'Society': [2634, 2640, 2879, 2887, 3009, 3014, 3018, 3027, 3069, 3075], 'International': [2639, 3074], '(9).References1.': [2643], 'Chobanian': [2644], 'AV,': [2645], 'Bakris': [2646, 2964], 'GL,': [2647], 'Black': [2648, 3023, 4247], 'HR,': [2649], 'Cushman': [2650, 2711], 'WC,': [2651, 2712], 'Green': [2652], 'LA,': [2653, 3481, 3483], 'Izzo': [2654], 'JL,': [2655, 2959], 'et': [2656, 2717, 2790, 2853, 2968, 3051, 3257, 3336, 3400, 3484, 3557, 4390], 'al;': [2657, 2791, 2854, 3337, 3401, 3485, 3558], 'Prevention,': [2668, 2686], 'Detection,': [2669, 2687], 'Evaluation,': [2670, 2688], 'Pressure.': [2676], 'Seventh': [2678], 'Pressure:': [2694], 'report.': [2698], 'JAMA.': [2699, 2745, 3318], '2003;289:2560-72.': [2700], '[PMID:': [2701, 2747, 2837, 2894, 3035, 3083, 3204, 3241, 3285, 3320, 3357, 3384, 3431, 3468, 3503, 3541, 3593, 3634], '12748199]': [2702], 'CrossrefMedlineGoogle': [2703, 2839, 2896, 3206, 3322, 3359, 3386, 3433, 3470, 3505, 3543, 3595, 3636], 'Scholar2.': [2704], 'James': [2705], 'PA,': [2706], 'Oparil': [2707], 'S,': [2708, 2758, 3046, 3252, 3546, 3598], 'Carter': [2709], 'BL,': [2710], 'Dennison-Himmelfarb': [2713], 'C,': [2714], 'Handler': [2715], 'J,': [2716, 2848], 'al.': [2718, 2969, 3052, 3258], '8).': [2744], '2013;:.': [2746, 3082, 3284], '24352797]': [2748], 'MedlineGoogle': [2749, 3037, 3085, 3243, 3287], 'Scholar3.': [2750], 'Graham': [2751], 'R,': [2752, 2844, 3256, 3327, 3477, 3600, 3604], 'Mancher': [2753], 'M,': [2754, 2785, 2852], 'Wolman': [2755], 'Greenfield': [2757], 'Steinberg': [2759], 'E;': [2760], 'Medicine.': [2763], 'Clinical': [2764, 2929, 2939, 2951, 2992, 3053, 4053], 'Practice': [2765, 3054, 3281], 'Guidelines': [2766, 2860, 3055, 3699, 4309], 'Can': [2768], 'Trust.': [2769], 'Washington,': [2770], 'DC:': [2771], 'Academies': [2773], 'Pr;': [2774], '2011.': [2775, 2953], 'Google': [2776, 2922, 2954, 3122, 3173], 'Scholar4.': [2777], 'DT,': [2779], 'Roccella': [2780], 'EJ,': [2781], 'Deutsch': [2782], 'AF,': [2783], 'Fornage': [2784], 'George': [2786], 'MG,': [2787], 'Howard': [2788], 'G,': [2789, 2842, 2965, 3250, 3440], 'Stroke': [2795, 2801, 2833], 'Council,': [2796], 'Council': [2797, 2803, 2812], 'Quality': [2805, 4253], 'Care': [2807], 'Outcomes': [2809], 'Research,': [2810], 'Functional': [2814], 'Genomics': [2815], 'Translational': [2817, 4105], 'Biology.': [2818], 'Factors': [2819], 'influencing': [2820], 'mortality:': [2825, 3618], 'statement': [2827], 'Association/American': [2832], 'Association.': [2834], 'Stroke.': [2835, 3539], '2014;45:315-53.': [2836], '24309587]': [2838], 'Scholar5.': [2840], 'Mancia': [2841], 'Fagard': [2843], 'Narkiewicz': [2845], 'K,': [2846, 3397, 3399], 'Redón': [2847], 'Zanchetti': [2849, 3445, 3547], 'A,': [2850, 3510, 3548], 'Böhm': [2851], 'Task': [2855, 2868, 2989, 3278], 'Force': [2856, 2869, 2990, 3279], 'Members.': [2857], '2013': [2858, 2902, 3259], 'ESH/ESC': [2859], 'management': [2863, 2872, 2933], 'arterial': [2865, 2874, 3771], 'hypertension:': [2866, 4404, 4410], 'European': [2878, 2886, 3026], '(ESH)': [2882], '(ESC).': [2890], 'J': [2891, 3030, 3078, 3199, 3354, 3465, 3590], 'Hypertens.': [2892, 3466, 3591], '2013;31:1281-357.': [2893], '23817082]': [2895], 'Scholar6.': [2897], 'Canadian': [2898, 2903], 'Education': [2900, 2905], 'Program.': [2901], 'Program': [2906, 3312, 4255], '(CHEP)': [2907], 'Recommendations.': [2908], 'Markham,': [2909], 'Ontario,': [2910], 'Canada:': [2911], 'Canada;': [2913], '2012.': [2914], 'Accessed': [2915, 3166], 'www.hypertension.ca/chep-recommendations': [2917], '31': [2919], 'December': [2920], '2013.': [2921, 3121, 3165], 'Scholar7.': [2923], 'Excellence.': [2930], 'Hypertension:': [2931], 'adults.': [2938], 'guidelines:': [2940], 'methods,': [2941], 'recommendations.': [2944], 'London:': [2945], 'Excellence;': [2952], 'Scholar8.': [2955], 'Aronow': [2956], 'WS,': [2957], 'Fleg': [2958], 'Pepine': [2960], 'CJ,': [2961], 'Artinian': [2962], 'NT,': [2963], 'Brown': [2966], 'AS,': [2967], 'ACCF/AHA': [2970], '2011': [2971], 'document': [2974], 'elderly:': [2979, 3421], 'Expert': [2993], 'Consensus': [2994], 'documents': [2995], 'developed': [2996], 'collaboration': [2998], 'Academy': [3002], 'Neurology,': [3004], 'Geriatrics': [3006], 'Society,': [3007], 'Preventive': [3011], 'Cardiology,': [3012], 'Hypertension,': [3016, 4033], 'Nephrology,': [3020], 'Cardiologists,': [3024], 'Hypertension.': [3029, 3077, 3429], 'Am': [3031, 3200], 'Coll': [3032, 3201], 'Cardiol.': [3033, 3202], '2011;57:2037-114.': [3034], '21524875]': [3036], 'Scholar9.': [3038], 'Weber': [3039], 'MA,': [3040], 'Schiffrin': [3041], 'EL,': [3042], 'White': [3043, 4249], 'WB,': [3044], 'Mann': [3045], 'Lindholm': [3047], 'LH,': [3048], 'Kenerson': [3049], 'JG,': [3050], 'Community:': [3063], 'Statement': [3065], 'Clin': [3079], 'Hypertens': [3080, 3381], '(Greenwich).': [3081], '24341872]': [3084], 'Scholar10.': [3086], 'Nwankwo': [3087, 3216], 'T,': [3088, 3389, 3391, 3554], 'Yoon': [3089, 3214], 'SS,': [3090, 3215], 'Burt': [3091], 'V,': [3092, 3512], 'Gu': [3093], 'Q.': [3094], 'States:': [3101], 'Survey,': [3107, 4287], '2011-2012.': [3108], 'NCHS': [3109], 'brief': [3111], 'no.': [3112], '133.': [3113], 'Hyattsville,': [3114], 'MD:': [3115], 'Center': [3117, 4094], 'Statistics;': [3120], 'Scholar11.': [3123], 'Centers': [3124, 3159, 4367], 'Control': [3127, 3162, 4245, 4341, 4346, 4370, 4375], 'Prevention.': [3129], 'Response': [3131], 'Population': [3134, 3142], 'Totals.': [3135], 'Distribution': [3136], 'Civilian': [3139], 'Noninstitutionalized': [3140], 'Use': [3144], '2011-2012': [3148], 'Survey': [3149], 'Cycle:': [3150], 'Gender,': [3152], 'Age,': [3153], 'Race/Hispanic': [3155], 'Origin.': [3156], 'Atlanta,': [3157], 'GA:': [3158], 'Prevention;': [3164], 'www.cdc.gov/nchs/nhanes/response_rates_CPS.htm': [3168], '4': [3170], 'January': [3171, 4236], '2014.': [3172, 4237], 'Scholar12.': [3174], 'Guo': [3175], 'F,': [3176, 3550, 3552], 'He': [3177], 'D,': [3178, 3335], 'Zhang': [3179, 3437, 3443], 'W,': [3180, 3442], 'Walton': [3181], 'RG.': [3182], 'Trends': [3183], 'prevalence,': [3185], 'awareness,': [3186], 'management,': [3187], 'adults,': [3195], '2010.': [3198], '2012;60:599-606.': [3203], '22796254]': [3205], 'Scholar13.': [3207], 'JD,': [3209], 'Hughes': [3210], 'JP,': [3211], 'Ostchega': [3212], 'Y,': [3213, 3438], 'Mean': [3218], '18': [3227], '2001–2008.': [3234], 'Natl': [3235], 'Stat': [3237], 'Report.': [3238], '2011;:1-22,': [3239], '24.': [3240], '21485611]': [3242], 'Scholar14.': [3244], 'Goff': [3245], 'DC,': [3246], 'Lloyd-Jones': [3247], 'Bennett': [3249], 'Coady': [3251], "D'Agostino": [3253], 'RB,': [3254], 'Gibbons': [3255], 'ACC/AHA': [3260], 'Assessment': [3264], 'Risk:': [3267], 'Cardiology/American': [3275], 'Guidelines.': [3282], 'Circulation.': [3283], '24222018]': [3286], 'Scholar15.': [3288], 'drug': [3294], 'Final': [3303], '(SHEP).': [3313], 'Cooperative': [3315], 'Research': [3316, 4106], 'Group.': [3317, 3340, 3363, 3409, 3449, 3488], '1991;265:3255-64.': [3319], '2046107]': [3321], 'Scholar16.': [3323], 'Beckett': [3324], 'NS,': [3325], 'Peters': [3326], 'Fletcher': [3328], 'AE,': [3329], 'Staessen': [3330], 'JA,': [3331], 'Liu': [3332, 3435, 3439], 'L,': [3333, 3436], 'Dumitrascu': [3334], 'Study': [3339, 3362, 3408, 3448, 3487], 'older.': [3351], 'N': [3352], 'Engl': [3353], 'Med.': [3355], '2008;358:1887-98.': [3356], '18378519]': [3358], 'Scholar17.': [3360], 'Principal': [3364], 'assess': [3371], 'optimal': [3372], '(JATOS).': [3380], 'Res.': [3382], '2008;31:2115-27.': [3383], '19139601]': [3385], 'Scholar18.': [3387], 'Ogihara': [3388], 'Saruta': [3390], 'Rakugi': [3392], 'H,': [3393, 3395], 'Matsuoka': [3394], 'Shimamoto': [3396], 'Shimada': [3398], 'Valsartan': [3402], 'Target': [3410], 'valsartan': [3422], 'study.': [3428], '2010;56:196-202.': [3430], '20530299]': [3432], 'Scholar19.': [3434], 'Li': [3441], 'X,': [3444], 'A;': [3446], 'Felodipine': [3451], 'Reduction': [3453], '(FEVER)': [3454], 'Study:': [3455], 'randomized': [3457, 3536, 3588], 'long-term': [3458], 'placebo-controlled': [3459], 'patients.': [3464, 3855], '2005;23:2157-72.': [3467], '16269957]': [3469], 'Scholar20.': [3471], 'Benavente': [3472], 'OR,': [3473], 'Coffey': [3474], 'CS,': [3475], 'Conwit': [3476], 'Hart': [3478], 'RG,': [3479], 'McClure': [3480], 'Pearce': [3482], 'Blood-pressure': [3489], 'lacunar': [3495], 'stroke:': [3496], 'randomised': [3499], 'Lancet.': [3501, 3632], '2013;382:507-15.': [3502], '23726159]': [3504], 'Scholar21.': [3506], 'Sipahi': [3507], 'I,': [3508], 'Swaminathan': [3509], 'Natesan': [3511], 'Debanne': [3513], 'SM,': [3514], 'Simon': [3515], 'DI,': [3516], 'Fang': [3517], 'JC.': [3518], 'Effect': [3519], 'incident': [3524], 'cohorts': [3527], 'prehypertensive': [3529], 'levels:': [3532], 'trials.': [3538, 3589], '2012;43:432-40.': [3540], '22156683]': [3542], 'Scholar22.': [3544], 'Czernichow': [3545], 'Turnbull': [3549], 'Barzi': [3551], 'Ninomiya': [3553], 'Kengne': [3555], 'AP,': [3556], 'Lowering': [3561], "Trialists'": [3563], 'Collaboration.': [3564, 3609], 'pressure-lowering': [3575], 'regimens': [3576], 'according': [3581], 'pressure:': [3585], '2011;29:4-16.': [3592], '20881867]': [3594], 'Scholar23.': [3596], 'Lewington': [3597], 'Clarke': [3599], 'Qizilbash': [3601], 'N,': [3602], 'Peto': [3603], 'Collins': [3605], 'R;': [3606], 'Prospective': [3607], 'Studies': [3608], 'Age-specific': [3610], 'relevance': [3611], 'usual': [3613], 'vascular': [3617], 'individual': [3622], '61': [3629], 'prospective': [3630, 4323], '2002;360:1903-13.': [3633], '12493255]': [3635], 'Scholar': [3637], 'Comments0': [3638], 'CommentsSign': [3639], 'Submit': [3642], 'Comment': [3644, 3651], 'Zrinko': [3645, 3856], 'Petrak,': [3646, 3857], 'MDWaikoloa,': [3647], 'Hawaii30': [3648], 'article': [3655, 4176, 4227], 'published': [3656, 4229], '1,': [3660], 'Annals': [3665], 'Internal': [3667], 'entitled': [3669], '"EVIDENCE': [3670], 'SUPPORTING': [3671], 'SYSTOLIC': [3673], 'PRESSURE': [3674], 'GOAL': [3675], 'OF': [3676, 4291], 'LESS': [3677], 'THAN': [3678], 'MMHG': [3680], 'IN': [3681, 4293, 4301], 'PATIENTS': [3682, 4295], 'AGED': [3683], 'YEARS': [3685], 'OR': [3686], 'OLDER:': [3687], 'THE': [3688], 'MINORITY': [3689], 'VIEW",': [3690], 'disagree': [3694], 'Adults': [3708, 4250], 'mmHg': [3722, 3745, 3791, 3800, 3811, 3829], 'disease.': [3736], 'lowering': [3738], 'elevated': [3739], 'wide': [3751], 'pulse': [3752], '(PP)': [3754], ',': [3755], 'lead': [3757], 'compromise': [3760], 'vital': [3763], 'organs': [3764], 'perfusion': [3765], 'pressures,': [3766], '(MAP)': [3773], 'generally': [3778], 'value': [3780], '70-110': [3782], 'mmHG.': [3783], 'Example:': [3784], '75-year-old': [3785], 'BP': [3788, 3794, 3826], '143/18': [3790], 'PP:': [3792], '(systolic': [3793], '-': [3795], 'Diastolic': [3796], 'BP)': [3797, 3805], 'MAP:': [3801], '[': [3802], '(2X': [3803], '+': [3806], 'SBP/3': [3807], ']': [3808], '59.6': [3810], 'Also,': [3812], 'when': [3813], 'accompanied': [3818], 'severe': [3820], 'aortic': [3821, 3844], 'stenosis,': [3822], 'maintaing': [3823], 'necessary': [3832], 'cases,': [3835], 'order': [3837], 'overcome': [3839], 'very': [3840], 'trans': [3842], 'valvular': [3843], 'valve': [3845], 'gradient': [3846], 'present': [3850], 'M.D.': [3858], 'Waikoloa,': [3859], 'Hawaii': [3860], 'Author,': [3861], 'InformationAuthors:': [3865], 'Jackson': [3866, 4002], 'WrightJr.,': [3868], 'PhD;': [3870], 'DrPH;': [3875, 3879], 'MS;': [3884], 'ANPAffiliations:': [3891], 'Maryland.Disclaimer:': [3933], 'views': [3935], 'expressed': [3936], 'paper': [3939], 'necessarily': [3948], 'reflect': [3949], 'Department': [3963], 'Human': [3967], 'Services.Acknowledgment:': [3968], 'thank': [3971], 'Dr.': [3972, 4027], 'Michael': [3973], 'Mussolino,': [3974], 'Division': [3981, 4029, 4049], 'Sciences,': [3984, 4052], 'Epidemiology': [3985], 'Branch,': [3986, 4057], 'his': [3988], 'data.Disclosures:': [3994], 'Disclosures': [3995], 'can': [3996], 'viewed': [3998], 'www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-2981.Corresponding': [4000], 'Author:': [4001], 'Hospitals': [4009, 4035], 'Center,': [4012, 4038], 'Bolwell': [4013, 4039], 'Suite': [4014, 4040], '2200,': [4015, 4041], '11100': [4016, 4042], 'Euclid': [4017, 4043], 'Avenue,': [4018, 4044], 'OH': [4020, 4046], '44106-6053;': [4021], 'e-mail,': [4022], 'Jackson.[email': [4023], 'protected]edu.Current': [4024], 'Author': [4025], 'Addresses:': [4026], 'Wright:': [4028], 'Nephrology': [4031], '44106-6053.Dr.': [4047], 'Fine:': [4048], 'Applications': [4054], 'Institutes': [4065], 'Health,': [4067], 'Two': [4068], 'Rockledge': [4069, 4074], 'Centre,': [4070], 'Room': [4071, 4112], '10216,': [4072], '6701': [4073], 'Drive,': [4075], 'MSC': [4076], '7936,': [4077], 'MD': [4079, 4131], '20892-7936.Dr.': [4080], 'Lackland:': [4081], 'Cannon': [4088], 'Street,': [4089, 4111, 4129], 'SC': [4091], '29425.Dr.': [4092], 'Ogedegbe:': [4093], 'Healthful': [4096], 'Behavior': [4097], 'Change,': [4098], 'Building,': [4107], '227': [4108], 'East': [4109], '30th': [4110], '633,': [4113], 'NY': [4116], '10010.Dr.': [4117], 'Himmelfarb:': [4119], '525': [4126], 'North': [4127], 'Wolfe': [4128], '21205.Author': [4132], 'Contributions:': [4133], 'Conception': [4134], 'design:': [4136], 'J.T.': [4137, 4153, 4165, 4181, 4196, 4211, 4220], 'Wright,': [4138, 4154, 4166, 4182, 4197, 4212, 4221], 'L.J.': [4139, 4155, 4167, 4183, 4198, 4222], 'D.T.': [4141, 4157, 4169, 4185, 4200], 'G.': [4143, 4171, 4187, 4202], 'C.R.': [4145, 4159, 4189, 4204, 4213, 4224], 'Himmelfarb.Analysis': [4147], 'interpretation': [4149], 'data:': [4152, 4219], 'Himmelfarb.Drafting': [4161], 'article:': [4164, 4195], 'Ogedegbe.Critical': [4172], 'revision': [4173], 'important': [4178], 'intellectual': [4179], 'content:': [4180], 'Himmelfarb.Final': [4191], 'approval': [4192], 'Himmelfarb.Administrative,': [4206], 'technical,': [4207], 'logistic': [4209], 'support:': [4210], 'Himmelfarb.Collection': [4215], 'assembly': [4217], 'Himmelfarb.This': [4226], 'online': [4230], 'first': [4231], 'www.annals.org': [4233], '14': [4235], 'PreviousarticleNextarticle': [4238], 'Advertisement': [4239], 'FiguresReferencesRelatedDetails': [4240], 'Metrics': [4241], 'Cited': [4242], 'byBlood': [4243], 'Following': [4251], 'Improvement': [4254], 'Large': [4258], 'Integrated': [4259], 'SystemAtherosclerotic': [4261], 'Adult:': [4268], 'Part': [4269], '1Trends': [4270], 'gout:': [4278], '2007–2018DRUG': [4288], 'USAGE': [4289], 'PATTERN': [4290], 'ANTIHYPERTENSIVES': [4292], 'DIABETIC': [4294], '–': [4296], 'CROSS-SECTIONAL': [4298], 'OPD-BASED': [4299], 'STUDY': [4300], 'TERTIARY': [4303], 'CARE': [4304], 'SET-UPThe': [4305], 'Evolution': [4306], 'Over': [4310], 'Last': [4312], '20+': [4313], 'Years:': [4314], 'Comprehensive': [4316], 'ReviewAdherence': [4317], 'care': [4320], 'cohort': [4327], 'outcomesThe': [4332], 'Continuing': [4333], 'Challenge': [4334], 'Low': [4336], 'US': [4343, 4348], 'AdultsBlood': [4344], 'Adults,': [4349], '2009': [4350], '2012': [4352], 'Through': [4353], '2017': [4354], '2020Proceedings': [4356], 'Workshop': [4373], 'HypertensionPrise': [4376], 'en': [4377, 4382], 'charge': [4378], 'de': [4379], 'l’hypertension': [4380], 'artérielle': [4381], 'prévention': [4383], 'cardiovasculaire': [4384], 'primaire': [4385], 'chez': [4386], 'les': [4387], 'personnes': [4388], 'âgées': [4389], 'très': [4391], 'âgéesHypertensionEffect': [4392], 'Melissa': [4394], 'officinalis': [4395], 'essential': [4403], 'double‐blind': [4406], 'crossover': [4407], 'trialTreating': [4409], 'spe': [4412]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2168291682', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 20}, {'year': 2018, 'cited_by_count': 22}, {'year': 2017, 'cited_by_count': 39}, {'year': 2016, 'cited_by_count': 53}, {'year': 2015, 'cited_by_count': 69}, {'year': 2014, 'cited_by_count': 69}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-09T13:43:29.007215', 'created_date': '2016-06-24'}