Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2165374523', 'doi': 'https://doi.org/10.1186/1475-2875-10-42', 'title': 'Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum', 'display_name': 'Sequence and gene expression of chloroquine resistance transporter (pfcrt) in the association of in vitro drugs resistance of Plasmodium falciparum', 'publication_year': 2011, 'publication_date': '2011-02-15', 'ids': {'openalex': 'https://openalex.org/W2165374523', 'doi': 'https://doi.org/10.1186/1475-2875-10-42', 'mag': '2165374523', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21320353', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3055224'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1475-2875-10-42', 'pdf_url': 'https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-10-42', 'source': {'id': 'https://openalex.org/S93003929', 'display_name': 'Malaria Journal', 'issn_l': '1475-2875', 'issn': ['1475-2875'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-10-42', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070911108', 'display_name': 'Wanna Chai่jaroenkul', 'orcid': 'https://orcid.org/0000-0002-3720-3878'}, 'institutions': [{'id': 'https://openalex.org/I108108428', 'display_name': 'Thammasat University', 'ror': 'https://ror.org/002yp7f20', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I108108428']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Wanna Chaijaroenkul', 'raw_affiliation_strings': ['Faculty of Allied Health Sciences, Thammasat University, Rangsit, Patumthani, 12120, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Allied Health Sciences, Thammasat University, Rangsit, Patumthani, 12120, Thailand', 'institution_ids': ['https://openalex.org/I108108428']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061182167', 'display_name': 'Stephen A. Ward', 'orcid': 'https://orcid.org/0000-0003-2331-3192'}, 'institutions': [{'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Stephen A Ward', 'raw_affiliation_strings': ['Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK', 'institution_ids': ['https://openalex.org/I146655781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065169507', 'display_name': 'Mathirut Mungthin', 'orcid': 'https://orcid.org/0000-0002-6372-9857'}, 'institutions': [{'id': 'https://openalex.org/I4210087968', 'display_name': 'Phramongkutklao Hospital', 'ror': 'https://ror.org/007h1qz76', 'country_code': 'TH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087968']}, {'id': 'https://openalex.org/I4401726974', 'display_name': 'Phramongkutklao College of Medicine', 'ror': 'https://ror.org/04md5yc36', 'country_code': None, 'type': 'education', 'lineage': ['https://openalex.org/I4401726974']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Mathirut Mungthin', 'raw_affiliation_strings': ['Department of Parasitology, Phramongkutklao College of Medicine, Ratchathewi, Bangkok, 10400, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Department of Parasitology, Phramongkutklao College of Medicine, Ratchathewi, Bangkok, 10400, Thailand', 'institution_ids': ['https://openalex.org/I4210087968', 'https://openalex.org/I4401726974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051718429', 'display_name': 'David J. Johnson', 'orcid': 'https://orcid.org/0000-0003-4537-1748'}, 'institutions': [{'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'David Johnson', 'raw_affiliation_strings': ['Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK', 'institution_ids': ['https://openalex.org/I146655781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066429649', 'display_name': 'Andrew Owen', 'orcid': 'https://orcid.org/0000-0002-9819-7651'}, 'institutions': [{'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Andrew Owen', 'raw_affiliation_strings': ['Department of Pharmacology and Therapeutics, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology and Therapeutics, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK', 'institution_ids': ['https://openalex.org/I146655781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113948583', 'display_name': 'Patrick G. Bray', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Patrick G Bray', 'raw_affiliation_strings': ['Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Biochemical Parasitology of Liverpool, University of Liverpool, Pembroke Place, Liverpool, L35QA, UK', 'institution_ids': ['https://openalex.org/I146655781']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5002736566', 'display_name': 'Kesara Na‐Bangchang', 'orcid': 'https://orcid.org/0000-0001-6389-0897'}, 'institutions': [{'id': 'https://openalex.org/I108108428', 'display_name': 'Thammasat University', 'ror': 'https://ror.org/002yp7f20', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I108108428']}], 'countries': ['TH'], 'is_corresponding': False, 'raw_author_name': 'Kesara Na-Bangchang', 'raw_affiliation_strings': ['Faculty of Allied Health Sciences, Thammasat University, Rangsit, Patumthani, 12120, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Allied Health Sciences, Thammasat University, Rangsit, Patumthani, 12120, Thailand', 'institution_ids': ['https://openalex.org/I108108428']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1890, 'currency': 'GBP', 'value_usd': 2318, 'provenance': 'doaj'}, 'apc_paid': {'value': 1890, 'currency': 'GBP', 'value_usd': 2318, 'provenance': 'doaj'}, 'fwci': 3.862, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 38, 'citation_normalized_percentile': {'value': 0.921039, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '10', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11465', 'display_name': 'Drug-Induced Hepatotoxicity and Protection', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10570', 'display_name': 'Drug Transport and Resistance Mechanisms', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/parasitology', 'display_name': 'Parasitology', 'score': 0.66966635}], 'concepts': [{'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.8452108}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7827784}, {'id': 'https://openalex.org/C2777425658', 'wikidata': 'https://www.wikidata.org/wiki/Q422438', 'display_name': 'Chloroquine', 'level': 3, 'score': 0.70437145}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.6737357}, {'id': 'https://openalex.org/C190612196', 'wikidata': 'https://www.wikidata.org/wiki/Q180502', 'display_name': 'Parasitology', 'level': 2, 'score': 0.66966635}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.5886028}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.5487946}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.48489386}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.48428768}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.48180193}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.44793594}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.15150824}, {'id': 'https://openalex.org/C90856448', 'wikidata': 'https://www.wikidata.org/wiki/Q431', 'display_name': 'Zoology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002738', 'descriptor_name': 'Chloroquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017125', 'descriptor_name': 'Genes, Protozoan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005838', 'descriptor_name': 'Genotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011110', 'descriptor_name': 'Polymorphism, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013785', 'descriptor_name': 'Thailand', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1475-2875-10-42', 'pdf_url': 'https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-10-42', 'source': {'id': 'https://openalex.org/S93003929', 'display_name': 'Malaria Journal', 'issn_l': '1475-2875', 'issn': ['1475-2875'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3055224', 'pdf_url': 'https://europepmc.org/articles/pmc3055224?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055224', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://archive.lstmed.ac.uk/2018/1/Ward-Malaria-J-11.pdf', 'pdf_url': 'https://archive.lstmed.ac.uk/2018/1/Ward-Malaria-J-11.pdf', 'source': {'id': 'https://openalex.org/S4306400185', 'display_name': 'LSTM Online Archive (Liverpool School of Tropical Medicine)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I194839184', 'host_organization_name': 'Liverpool School of Tropical Medicine', 'host_organization_lineage': ['https://openalex.org/I194839184'], 'host_organization_lineage_names': ['Liverpool School of Tropical Medicine'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21320353', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1475-2875-10-42', 'pdf_url': 'https://malariajournal.biomedcentral.com/counter/pdf/10.1186/1475-2875-10-42', 'source': {'id': 'https://openalex.org/S93003929', 'display_name': 'Malaria Journal', 'issn_l': '1475-2875', 'issn': ['1475-2875'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W139561384', 'https://openalex.org/W1544864283', 'https://openalex.org/W1594650890', 'https://openalex.org/W1672791537', 'https://openalex.org/W1815038235', 'https://openalex.org/W1889531862', 'https://openalex.org/W1966124517', 'https://openalex.org/W1969503178', 'https://openalex.org/W1972177048', 'https://openalex.org/W1979306828', 'https://openalex.org/W1980975034', 'https://openalex.org/W1994981343', 'https://openalex.org/W1996323490', 'https://openalex.org/W2008166606', 'https://openalex.org/W2014392076', 'https://openalex.org/W2021258341', 'https://openalex.org/W2028704380', 'https://openalex.org/W2031908013', 'https://openalex.org/W2037350416', 'https://openalex.org/W2048404226', 'https://openalex.org/W2055527040', 'https://openalex.org/W2063527491', 'https://openalex.org/W2078607899', 'https://openalex.org/W2078887155', 'https://openalex.org/W2087000723', 'https://openalex.org/W2094103969', 'https://openalex.org/W2097263871', 'https://openalex.org/W2101036752', 'https://openalex.org/W2105668259', 'https://openalex.org/W2108545589', 'https://openalex.org/W2116892626', 'https://openalex.org/W2123663357', 'https://openalex.org/W2124883243', 'https://openalex.org/W2131867921', 'https://openalex.org/W2132923209', 'https://openalex.org/W2135192999', 'https://openalex.org/W2140026920', 'https://openalex.org/W2160778580', 'https://openalex.org/W2161338325', 'https://openalex.org/W2166641658', 'https://openalex.org/W2167433327', 'https://openalex.org/W2169362895', 'https://openalex.org/W2217354070', 'https://openalex.org/W2333050857', 'https://openalex.org/W37545008'], 'related_works': ['https://openalex.org/W47752255', 'https://openalex.org/W2465887096', 'https://openalex.org/W2414493761', 'https://openalex.org/W2401334429', 'https://openalex.org/W2366318376', 'https://openalex.org/W2184471406', 'https://openalex.org/W2166046803', 'https://openalex.org/W2144038468', 'https://openalex.org/W2113822524', 'https://openalex.org/W1141749753'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Plasmodium': [2], 'falciparum': [3, 38, 69], 'chloroquine': [4, 35, 46], 'resistance': [5, 33, 199, 202], '(CQR)': [6], 'transporter': [7], 'protein': [8], '(PfCRT)': [9], 'is': [10, 204], 'known': [11], 'to': [12, 34, 90, 179, 195], 'be': [13], 'the': [14, 29, 54, 76, 94, 110, 114, 169, 186, 196, 201], 'important': [15], 'key': [16], 'of': [17, 45, 53, 56, 64, 109, 172, 174, 198], 'CQR.': [18], 'Recent': [19], 'studies': [20], 'have': [21], 'definitively': [22], 'demonstrated': [23], 'a': [24, 62, 140], 'link': [25], 'between': [26, 168], 'mutations': [27, 42, 117, 133, 207], 'in': [28, 36, 75, 208], 'gene': [30, 159], 'pfcrt': [31, 91, 103, 156, 209], 'and': [32, 86, 123, 136, 157, 177], 'P.': [37, 68], '.': [39, 92, 210], 'Although': [40], 'these': [41, 175], 'are': [43, 49], 'predictive': [44, 52], 'resistance,': [47], 'they': [48], 'not': [50], 'quantitatively': [51], 'degree': [55, 197], 'resistance.': [57], 'Methods': [58], 'In': [59, 154], 'this': [60], 'study,': [61], 'total': [63], '95': [65, 96], 'recently': [66], 'adapted': [67], 'isolates': [70, 128], 'from': [71, 185], 'Thailand': [72], 'were': [73, 79, 99, 129, 146, 161], 'included': [74], 'analysis.': [77, 105], 'Parasites': [78], 'characterized': [80, 112], 'for': [81, 101], 'their': [82], 'drug': [83, 180], 'susceptibility': [84], 'phenotypes': [85], 'genotypes': [87], 'with': [88, 131], 'respect': [89], 'From': [93], 'original': [95], 'isolates,': [97], '20': [98], 'selected': [100], 'complete': [102, 126], 'sequence': [104], 'Results': [106], 'Almost': [107], 'all': [108], 'parasites': [111, 143], 'carried': [113], 'previously': [115], 'reported': [116], 'K76T,': [118], 'A220S,': [119], 'Q271E,': [120], 'N326S,': [121], 'I356T': [122], 'R371I.': [124], 'On': [125], 'sequencing,': [127], 'identified': [130], 'novel': [132], 'at': [134], 'K76A': [135], 'E198K.': [137], 'There': [138], 'was': [139, 181], 'suggestion': [141], 'that': [142, 151, 190], 'carrying': [144], 'E198K': [145], 'less': [147], 'resistant': [148], 'than': [149], 'those': [150], 'did': [152], 'not.': [153], 'addition,': [155], 'pfmdr1': [158], 'expression': [160, 170], 'investigated': [162], 'by': [163], 'real-time': [164], 'PCR.': [165], 'No': [166], 'relationship': [167], 'level': [171], 'either': [173], 'genes': [176, 192], 'response': [178], 'observed.': [182], 'Conclusion': [183], 'Data': [184], 'present': [187], 'study': [188], 'suggest': [189], 'other': [191], 'must': [193], 'contribute': [194], 'once': [200], 'phenotype': [203], 'established': [205], 'through': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2165374523', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-15T06:41:43.874362', 'created_date': '2016-06-24'}