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'1-Oct-2020.': [459], 'Bellisola': [460], 'G,': [461, 463, 467], 'Fracasso': [462], 'Ippoliti': [464], 'Menestrina': [466], 'Rosén': [468], 'A,': [469, 507, 509, 548, 667, 693, 703, 809], 'Soldà': [470], 'Udali': [472], 'Tomazzolli': [474], 'Tridente': [476], 'G': [477], 'Colombatti': [479], 'M': [480, 606], '(2004)': [481], 'Reductive': [482], 'activation': [483, 614], 'ricin': [485, 487], 'A-chain': [488], 'immunotoxins': [489], 'disulfide': [492, 738], 'isomerase': [493], 'thioredoxin': [495], 'reductase,': [496], 'Biochemical': [497], 'Pharmacology,': [498], '10.1016/j.bcp.2004.01.013,': [499], '67:9,': [500], '(1721-1731),': [501], '1-May-2004.': [505], 'Garcia': [506], 'Sekowski': [508], 'Subramanian': [510], 'Brasaemle': [513], 'D': [514], '(2003)': [515], 'Central': [517], 'Domain': [518], 'Is': [519, 611], 'Required': [520], 'Target': [522], 'Anchor': [524], 'Perilipin': [525], 'A': [526], 'Lipid': [528, 886], 'Droplets,': [529], 'Biological': [532], 'Chemistry,': [533], '10.1074/jbc.M206602200,': [534], '278:1,': [535], '(625-635),': [536], '1-Jan-2003.': [540], 'Koganesawa': [541], 'N,': [542, 797], 'Aizawa': [543], 'T,': [544, 550], 'Masaki': [545], 'Matsuura': [547], 'Nimori': [549], 'Bando': [551], 'Kawano': [553], 'K': [554, 557], 'Nitta': [556], '(2001)': [558, 610], 'Construction': [559], 'expression': [562, 580, 585, 870], 'system': [563], 'insect': [565], 'lysozyme': [566], 'lacking': [567], 'thermal': [568], 'stability:': [569], 'effect': [571], 'selection': [573], 'sequence': [576], 'level': [578], 'Pichia': [583], 'pastoris': [584], 'system,': [586], 'Protein': [587, 737, 839], 'Engineering,': [588], 'Design': [589], 'Selection,': [591], '10.1093/protein/14.9.705,': [592], '14:9,': [593], '(705-710),': [594], '1-Sep-2001.,': [598], '1-Sep-2001.': [602], 'Heyderman': [603], 'Soriani': [605], 'Hirst': [608], 'T': [609], 'immune': [612], 'missing': [616], 'link': [617], 'pathogenesis': [620], 'post-diarrhoeal': [622], 'HUS?,': [623], 'Trends': [624], 'Microbiology,': [626, 652], '10.1016/S0966-842X(01)02045-5,': [627], '9:6,': [628], '(262-266),': [629], '1-Jun-2001.': [633], 'Williams': [634], 'N': [635], '(2000)': [636], 'Immune': [637], 'modulation': [638], 'cholera-like': [641], 'enterotoxin': [642], 'B-subunits:': [643], 'adjuvant': [645], 'immunotherapeutic,': [647], 'International': [648], 'Medical': [651], '10.1016/S1438-4221(00)80062-4,': [653], '290:4-5,': [654], '(447-453),': [655], '1-Oct-2000.': [659], 'DeBose-Boyd': [660], 'Brown': [662], 'M,': [663, 799], 'Li': [664], 'W,': [665], 'Nohturfft': [666], 'Goldstein': [668], 'J': [669], 'Espenshade': [671], '(1999)': [673, 709, 736], 'Transport-Dependent': [674], 'Proteolysis': [675], 'SREBP,': [677], 'Cell,': [678], '10.1016/S0092-8674(00)81668-2,': [679], '99:7,': [680], '(703-712),': [681], '1-Dec-1999.': [685], 'White': [686], 'J,': [687, 762, 795, 807], 'Johannes': [688], 'L,': [689], 'Mallard': [690], 'F,': [691], 'Girod': [692], 'Grill': [694], 'Reinsch': [696], 'Keller': [698], 'P,': [699], 'Tzschaschel': [700], 'B,': [701], 'Echard': [702], 'Goud': [704], 'B': [705, 873], 'Stelzer': [707], 'E': [708, 822], 'Rab6': [710], 'Coordinates': [711], 'Novel': [713], 'Retrograde': [717], 'Transport': [718], 'Pathway': [719], 'Live': [721], 'Cells,': [722], 'Biology,': [726, 753], '10.1083/jcb.147.4.743,': [727], '147:4,': [728], '(743-760),': [729], '15-Nov-1999.': [733], 'Noiva': [734], 'R': [735, 837], 'isomerase:': [739], 'multifunctional': [741], 'redox': [742], 'chaperone': [743], 'reticulum,': [747], 'Seminars': [748], '&': [751], 'Developmental': [752], '10.1006/scdb.1999.0319,': [754], '10:5,': [755], '(481-493),': [756], '1-Oct-1999.': [760], 'Mastrianni': [761], 'Iannicola': [763], 'C,': [764, 803, 805], 'Myers': [765], 'DeArmond': [767, 810], 'Prusiner': [770, 813], '(1996)': [772, 815, 838, 868], 'Mutation': [773], 'prion': [776], 'gene': [778], 'at': [779], 'codon': [780], '208': [781], 'familial': [783], 'Creutzfeldt-Jakob': [784], 'disease,': [785], 'Neurology,': [786, 828], '10.1212/WNL.47.5.1305,': [787], '47:5,': [788], '(1305-1312),': [789], '1-Nov-1996.': [793], 'Tatzelt': [794], 'Maeda': [796], 'Pekny': [798], 'Yang': [800], 'Betsholtz': [802], 'Eliasson': [804], 'Cayetano': [806], 'Camerino': [808], 'Scrapie': [816], 'mice': [818], 'deficient': [819], 'apolipoprotein': [821, 872], 'glial': [824], 'fibrillary': [825], 'acidic': [826], 'protein,': [827], '10.1212/WNL.47.2.449,': [829], '47:2,': [830], '(449-453),': [831], '1-Aug-1996.': [835], 'Jaenicke': [836], 'association:': [842], 'In': [843], 'vitro': [844], 'studies': [845], 'self-organization': [847], 'targeting': [849], 'Current': [853], 'Topics': [854], 'Cellular': [856], 'Regulation': [857], 'Volume': [858], '34,': [859], '10.1016/S0070-2137(96)80008-2,': [860], '(209-314),': [861], '.': [862], 'Patel': [863], 'Grundy': [866], 'Heterologous': [869], 'carboxyl-terminal': [874], 'truncates:': [875], 'model': [877], 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