Publication Information

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3666, 4092, 4136, 4156, 4198, 4209, 4219, 4440, 4448, 4453, 4715, 4812, 4848, 4854, 4983, 5090, 5186, 5268, 5286, 5428, 5439, 5450, 5671, 5679, 5684, 5947, 6045, 6081, 6087, 6217, 6324, 6421, 6503, 6521], 'very': [6, 270], 'high': [7, 271], 'interstitial': [8, 272, 570, 2989], 'osmolarity': [9, 273, 571, 2258, 2990, 4680, 5912], 'leading': [10, 274, 2389, 2425, 4811, 4847, 6044, 6080], 'the': [12, 20, 38, 43, 56, 75, 101, 126, 157, 163, 176, 192, 217, 242, 276, 284, 302, 307, 320, 339, 365, 390, 421, 427, 440, 456, 481, 506, 561, 597, 612, 616, 619, 653, 660, 669, 673, 717, 725, 777, 863, 1237, 1247, 1369, 1396, 1466, 1502, 1662, 1675, 1684, 1693, 1696, 1701, 1717, 1723, 1737, 1770, 1782, 1791, 1992, 2059, 2062, 2103, 2108, 2149, 2172, 2176, 2191, 2199, 2247, 2294, 2306, 2320, 2365, 2370, 2374, 2387, 2401, 2433, 2523, 2566, 2616, 2669, 2720, 2732, 2769, 2773, 2777, 2929, 2957, 2968, 2972, 2980, 3016, 3031, 3035, 3038, 3072, 3079, 3088, 3092, 3136, 3144, 3196, 3283, 3657, 3667, 3789, 3816, 3886, 3923, 4083, 4096, 4105, 4114, 4117, 4122, 4138, 4144, 4158, 4192, 4204, 4213, 4414, 4481, 4484, 4525, 4530, 4571, 4594, 4598, 4613, 4621, 4669, 4716, 4728, 4742, 4787, 4792, 4796, 4809, 4823, 4855, 4945, 4988, 5038, 5091, 5142, 5154, 5191, 5195, 5199, 5351, 5379, 5390, 5394, 5422, 5434, 5443, 5645, 5712, 5715, 5756, 5761, 5802, 5825, 5829, 5845, 5853, 5901, 5948, 5960, 5974, 6020, 6025, 6029, 6042, 6056, 6088, 6178, 6222, 6272, 6325, 6377, 6389, 6426, 6430, 6434, 6587, 6615, 6626, 6630, 6643], 'activation': [13, 33, 122, 243, 277, 297, 386, 507, 1307, 1666, 1685, 1699, 1724, 1742, 2076, 2177, 2195, 2248, 2282, 2429, 2434, 2524, 2567, 2618, 2642, 2660, 2692, 2733, 2834, 2926, 2950, 3727, 4087, 4106, 4120, 4145, 4163, 4498, 4599, 4617, 4670, 4704, 4851, 4856, 4946, 4989, 5040, 5064, 5082, 5114, 5155, 5256, 5348, 5372, 5729, 5830, 5849, 5902, 5936, 6084, 6089, 6179, 6223, 6274, 6298, 6316, 6348, 6390, 6491, 6584, 6608], 'of': [14, 23, 28, 40, 62, 70, 78, 120, 128, 159, 184, 201, 212, 223, 244, 278, 287, 292, 304, 326, 334, 342, 384, 392, 423, 448, 465, 476, 487, 508, 532, 569, 596, 602, 606, 618, 655, 719, 727, 779, 811, 817, 1239, 1249, 1254, 1295, 1308, 1371, 1468, 1501, 1505, 1664, 1678, 1686, 1719, 1725, 1994, 2064, 2066, 2074, 2110, 2175, 2178, 2186, 2232, 2250, 2283, 2322, 2369, 2396, 2403, 2419, 2435, 2461, 2525, 2565, 2569, 2619, 2648, 2662, 2693, 2702, 2713, 2734, 2776, 2932, 2951, 2971, 2988, 3015, 3021, 3025, 3037, 3074, 3138, 3146, 3198, 3231, 3237, 3659, 3669, 3674, 3715, 3728, 3791, 3888, 3922, 3926, 4085, 4099, 4107, 4140, 4146, 4416, 4486, 4488, 4496, 4532, 4597, 4600, 4608, 4654, 4672, 4705, 4744, 4791, 4818, 4825, 4841, 4857, 4883, 4947, 4987, 4991, 5041, 5070, 5084, 5115, 5124, 5135, 5156, 5198, 5354, 5373, 5393, 5647, 5717, 5719, 5727, 5763, 5828, 5831, 5840, 5886, 5904, 5937, 5976, 6024, 6051, 6058, 6074, 6090, 6116, 6180, 6221, 6225, 6275, 6304, 6318, 6349, 6358, 6370, 6391, 6433, 6590, 6609, 6629, 6642], 'mitogen-activated': [15, 279, 552, 554], 'protein': [16, 280, 553, 555, 786, 1086, 1096, 3206, 3506, 3516], 'kinases': [17, 281, 803, 806, 812, 819, 878, 1080, 1087, 1091, 1097, 1241, 1297, 1507, 1688, 1727, 1759, 1800, 2068, 2081, 2112, 2147, 2180, 2194, 2236, 2308, 2359, 2437, 2571, 2664, 2695, 3223, 3226, 3232, 3239, 3298, 3500, 3507, 3511, 3517, 3661, 3717, 3928, 4109, 4148, 4181, 4222, 4490, 4503, 4534, 4569, 4602, 4616, 4658, 4730, 4781, 4859, 4993, 5086, 5117, 5411, 5453, 5721, 5734, 5765, 5800, 5833, 5848, 5890, 5962, 6014, 6092, 6227, 6320, 6351], '(MAPK).': [18, 282], 'However,': [19, 283, 1292, 2640, 3712, 5062, 6296], 'respective': [21, 285, 1676, 4097], 'roles': [22, 286], 'increased': [24, 74, 288, 338, 2256, 4678, 5910], 'intracellular': [25, 134, 239, 289, 398, 503, 661, 728, 769, 792, 1679, 2257, 2936, 3080, 3147, 3188, 3212, 4100, 4679, 5358, 5911, 6594], 'osmolality': [26, 135, 150, 290, 399, 414], 'and': [27, 83, 86, 108, 154, 175, 191, 247, 255, 291, 347, 350, 372, 418, 439, 455, 511, 519, 559, 666, 733, 755, 824, 839, 880, 890, 1089, 1106, 1312, 1406, 1464, 1700, 1733, 1743, 1923, 2037, 2102, 2234, 2252, 2268, 2271, 2285, 2422, 2490, 2522, 2527, 2556, 2653, 2704, 2771, 2827, 2829, 2916, 2919, 2978, 3085, 3152, 3174, 3244, 3259, 3300, 3310, 3509, 3526, 3732, 3826, 3884, 4121, 4154, 4164, 4345, 4459, 4524, 4656, 4674, 4690, 4693, 4707, 4844, 4912, 4944, 4949, 4978, 5075, 5126, 5193, 5249, 5251, 5338, 5341, 5576, 5690, 5755, 5888, 5906, 5922, 5925, 5939, 6077, 6145, 6177, 6182, 6212, 6309, 6360, 6428, 6484, 6486, 6574, 6577], 'cell': [29, 49, 145, 165, 235, 293, 313, 409, 429, 499, 592, 640, 645, 675, 1516, 1681, 1703, 1744, 1751, 1784, 1804, 2188, 2273, 2296, 2303, 2316, 2672, 2686, 2722, 2779, 2942, 2959, 2964, 3011, 3059, 3064, 3094, 3937, 4102, 4124, 4165, 4173, 4206, 4226, 4610, 4695, 4718, 4725, 4738, 5094, 5108, 5144, 5201, 5364, 5381, 5386, 5403, 5436, 5457, 5842, 5927, 5950, 5957, 5970, 6328, 6342, 6379, 6436, 6600, 6617, 6622], 'shrinkage': [30, 50, 146, 166, 294, 314, 410, 430, 641, 676, 1682, 1752, 2189, 2274, 2304, 2673, 2687, 3060, 3095, 4103, 4174, 4611, 4696, 4726, 5095, 5109, 5404, 5843, 5928, 5958, 6329, 6343], 'in': [31, 42, 105, 149, 231, 250, 295, 306, 369, 413, 495, 514, 627, 635, 713, 724, 796, 800, 1368, 1404, 1465, 1514, 1518, 1639, 1683, 1728, 1760, 1781, 1801, 2105, 2113, 2148, 2190, 2224, 2261, 2309, 2319, 2330, 2362, 2393, 2464, 2491, 2533, 2603, 2613, 2624, 2637, 2907, 2920, 2935, 2956, 3046, 3054, 3132, 3143, 3216, 3220, 3788, 3824, 3885, 3935, 3939, 4060, 4104, 4149, 4182, 4203, 4223, 4527, 4535, 4570, 4612, 4646, 4683, 4731, 4741, 4752, 4784, 4815, 4886, 4913, 4955, 5025, 5035, 5046, 5059, 5329, 5342, 5357, 5378, 5412, 5433, 5454, 5758, 5766, 5801, 5844, 5878, 5915, 5963, 5973, 5984, 6017, 6048, 6119, 6146, 6188, 6259, 6269, 6280, 6293, 6565, 6578, 6593, 6614], 'MAPK': [32, 41, 121, 296, 305, 385], 'are': [34, 298, 605, 611, 738, 782, 790, 804, 1298, 2024, 2082, 2559, 3024, 3030, 3157, 3201, 3210, 3224, 3718, 4446, 4504, 4981, 5677, 5735, 6215], 'not': [35, 141, 226, 238, 299, 405, 490, 502, 2207, 2212, 2265, 2608, 2844, 2928, 4629, 4634, 4687, 5030, 5266, 5350, 5861, 5866, 5919, 6264, 6501, 6586], 'known.': [36, 300], 'Similarly,': [37, 301], 'participation': [39, 303], 'regulatory': [44, 308, 547, 644, 1702, 2958, 3063, 4123, 5380, 6616], 'volume': [45, 104, 131, 139, 179, 194, 219, 309, 368, 395, 403, 443, 458, 483, 548, 593, 646, 671, 1704, 1745, 2242, 2263, 2317, 2404, 2780, 2960, 3012, 3065, 3090, 4125, 4166, 4664, 4685, 4739, 4826, 5202, 5382, 5896, 5917, 5971, 6059, 6437, 6618], 'increase': [46, 310, 549, 647, 659, 1705, 2104, 2392, 2934, 2961, 3066, 3078, 4126, 4526, 4814, 5356, 5383, 5757, 6047, 6592, 6619], '(RVI)': [47, 311], 'following': [48, 312, 2200, 4622, 5854], 'remains': [51, 315, 2863, 5285, 6520], 'be': [53, 317, 1366, 1402, 1672, 2373, 2378, 2666, 2865, 3786, 3822, 4093, 4795, 4800, 5088, 5287, 6028, 6033, 6322, 6522], 'investigated.': [54, 318, 1708, 4129], 'In': [55, 111, 156, 229, 319, 375, 420, 493, 860, 1362, 1763, 2058, 2576, 2683, 2944, 3280, 3782, 4185, 4480, 4998, 5105, 5366, 5415, 5711, 6232, 6339, 6559, 6602], 'rat': [57, 232, 321, 496, 1641, 1761, 2020, 2150, 2310, 2534, 2908, 2973, 4062, 4183, 4442, 4572, 4732, 4956, 5330, 5395, 5413, 5673, 5803, 5964, 6189, 6566, 6631], 'medullary': [58, 322, 528, 598, 3017], 'thick': [59, 323, 529, 599, 3018], 'ascending': [60, 324, 530, 600, 3019], 'limb': [61, 325, 531, 601, 3020], 'Henle': [63, 327, 533, 603, 3022], '(MTAL),': [64, 328], 'extracellular': [65, 79, 253, 329, 343, 517, 538, 638, 874, 876, 1509, 1668, 1690, 1755, 1788, 2027, 2182, 2381, 2562, 2912, 3057, 3294, 3296, 3930, 4089, 4111, 4177, 4210, 4449, 4604, 4803, 4984, 5334, 5407, 5440, 5680, 5835, 6036, 6218, 6570], 'hypertonicity': [66, 330, 1510, 1669, 1756, 1793, 2382, 2439, 2457, 3931, 4090, 4178, 4215, 4804, 4861, 4879, 5408, 5446, 6037, 6094, 6112], 'produced': [67, 331], 'by': [68, 332, 885, 1101, 1471, 1508, 1667, 1689, 1731, 1754, 2181, 2198, 2438, 2610, 2621, 2634, 2675, 2941, 3305, 3521, 3891, 3929, 4088, 4110, 4152, 4176, 4603, 4620, 4860, 5032, 5043, 5056, 5097, 5363, 5406, 5834, 5852, 6093, 6266, 6277, 6290, 6331, 6599], 'addition': [69, 333], 'NaCl': [71, 335, 2623, 2826, 5045, 5248, 6279, 6483], 'or': [72, 336, 747, 892, 2859, 3166, 3312, 5281, 6516], 'sucrose': [73, 95, 337, 359, 2631, 2677, 5053, 5099, 6287, 6333], 'phosphorylation': [76, 340, 816, 836, 1253, 2065, 2106, 2460, 2858, 3236, 3256, 3673, 4487, 4528, 4882, 5280, 5718, 5759, 6115, 6515], 'level': [77, 341, 2063, 2249, 2661, 4485, 4671, 5083, 5716, 5903, 6317], 'signal-regulated': [80, 344, 539, 877, 3297], 'kinase': [81, 85, 93, 249, 262, 345, 349, 357, 513, 526, 540, 543, 556, 788, 821, 822, 823, 826, 832, 865, 1316, 1400, 1698, 1741, 1774, 2529, 2655, 2706, 2833, 2852, 2918, 2953, 3208, 3241, 3242, 3243, 3246, 3252, 3285, 3736, 3820, 4119, 4162, 4196, 4951, 5077, 5128, 5255, 5274, 5340, 5375, 5426, 6184, 6311, 6362, 6490, 6509, 6576, 6611], '(ERK)': [82, 346, 882, 3302], 'p38': [84, 248, 261, 348, 512, 525, 1090, 1399, 1773, 2235, 2253, 2269, 2286, 2528, 2654, 2705, 2832, 2851, 2917, 2952, 3510, 3819, 4195, 4657, 4675, 4691, 4708, 4950, 5076, 5127, 5254, 5273, 5339, 5374, 5425, 5889, 5907, 5923, 5940, 6183, 6310, 6361, 6489, 6508, 6575, 6610], 'a': [88, 106, 209, 352, 370, 473, 643, 809, 814, 830, 834, 1778, 2138, 2221, 2228, 2573, 2690, 2698, 2727, 2848, 2872, 2875, 2921, 2963, 3062, 3229, 3234, 3250, 3254, 4200, 4560, 4643, 4650, 4995, 5112, 5120, 5149, 5270, 5294, 5297, 5343, 5385, 5430, 5791, 5875, 5882, 6229, 6346, 6354, 6384, 6505, 6529, 6532, 6579, 6621], 'lesser': [89, 353, 2922, 5344, 6580], 'extent': [90, 119, 127, 354, 383, 391, 2923, 5345, 6581], 'c-Jun': [91, 355, 541, 1078, 3498], 'NH2-terminal': [92, 356, 542, 1079, 3499], 'with': [94, 125, 358, 389, 894, 1918, 1991, 2137, 2246, 2280, 2578, 2615, 2680, 2697, 2825, 3314, 4340, 4413, 4559, 4668, 4702, 5000, 5037, 5102, 5119, 5247, 5571, 5644, 5790, 5900, 5934, 6234, 6271, 6336, 6353, 6482], 'only.': [96, 360], 'Both': [97, 361], 'hypertonic': [98, 113, 362, 377, 1107, 2217, 2238, 2611, 2622, 2630, 2676, 2681, 2802, 2911, 3527, 4639, 4660, 5033, 5044, 5052, 5098, 5103, 5224, 5333, 5871, 5892, 6267, 6278, 6286, 6332, 6337, 6459, 6569], 'solutions': [99, 363], 'decreased': [100, 364], 'MTAL': [102, 129, 177, 366, 393, 441, 1642, 1729, 2021, 2114, 2187, 2311, 2535, 2555, 2604, 2638, 2684, 2724, 2796, 2909, 4063, 4150, 4443, 4536, 4609, 4733, 4957, 4977, 5026, 5060, 5106, 5146, 5218, 5331, 5674, 5767, 5841, 5965, 6190, 6211, 6260, 6294, 6340, 6381, 6453, 6567], 'cellular': [103, 130, 138, 178, 193, 218, 367, 394, 402, 442, 457, 482, 670, 2209, 2225, 2241, 2262, 2323, 2363, 2462, 2574, 2714, 3089, 4631, 4647, 4663, 4684, 4745, 4785, 4884, 4996, 5136, 5863, 5879, 5895, 5916, 5977, 6018, 6117, 6230, 6371], 'dose-': [107, 371], 'time-dependent': [109, 373], 'manner.': [110, 374], 'contrast,': [112, 376], 'urea': [114, 378], 'had': [115, 379], 'no': [116, 380], 'effect.': [117, 381], 'was': [123, 167, 180, 387, 431, 444, 2069, 2227, 2243, 2278, 2289, 2643, 2927, 2939, 4491, 4649, 4665, 4700, 4711, 5065, 5349, 5361, 5722, 5881, 5897, 5932, 5943, 6299, 6585, 6597], 'correlated': [124, 388, 2245, 4667, 5899], 'decrease.': [132, 396], 'Increasing': [133, 397], 'without': [136, 147, 400, 411, 2259, 4681, 5913], 'modifying': [137, 401], 'did': [140, 225, 404, 489, 2206, 2211, 2264, 4628, 4633, 4686, 5860, 5865, 5918], 'activate': [142, 406, 1798, 2213, 2266, 4220, 4635, 4688, 5451, 5867, 5920], 'MAPK,': [143, 407], 'whereas': [144, 221, 408, 485], 'variation': [148, 412], 'activated': [151, 415, 795, 807, 884, 1100, 2609, 3215, 3227, 3304, 3520, 5031, 6265], 'both': [152, 245, 416, 509, 2554, 2649, 4976, 5071, 6210, 6305], 'ERK': [153, 224, 246, 417, 488, 510, 2233, 2251, 2267, 2284, 2526, 2650, 2703, 2841, 2915, 4655, 4673, 4689, 4706, 4948, 5072, 5125, 5263, 5337, 5887, 5905, 5921, 5938, 6181, 6306, 6359, 6498, 6573], 'p38.': [155, 419], 'presence': [158, 422], '600': [160, 424, 2032, 4454, 5685], 'mosmol/liter': [161, 425, 2033, 4455, 5686], 'NaCl,': [162, 426, 2612, 5034, 6268], 'maximal': [164, 428], 'observed': [168, 432], 'after': [169, 205, 433, 469, 2800, 5222, 6457], '10': [170, 434], 'min': [171, 435], 'at': [172, 436], '37': [173, 437], '°C': [174, 438], 'reduced': [181, 445], '70%': [183, 447], 'its': [185, 202, 449, 466], 'initial': [186, 203, 450, 467, 674, 2295, 2721, 2778, 3093, 4717, 5143, 5200, 5949, 6378, 6435], 'value.': [187, 451], 'Then,': [188, 452], 'RVI': [189, 257, 453, 521, 650, 2708, 2728, 2799, 3069, 5130, 5150, 5221, 6365, 6385, 6456], 'occurred': [190, 454], 'progressively': [195, 459], 'recovered': [196, 460], 'reach': [198, 462], 'about': [199, 463, 2635, 5057, 6291], '90%': [200, 464], 'value': [204, 468], '30': [206, 470], 'min.': [207, 471], 'SB203580,': [208, 472], 'specific': [210, 474], 'inhibitor': [211, 475], 'p38,': [213, 477], 'almost': [214, 478], 'completely': [215, 479], 'inhibited': [216, 480], 'recovery,': [220, 484], 'inhibition': [222, 486], 'alter': [227, 491, 2208, 4630, 5862], 'RVI.': [228, 492, 5444], 'conclusion,': [230, 494, 2902, 5324, 6560], 'MTAL:': [233, 497], '1)': [234, 498, 1714, 2202, 4135, 4624, 5856], 'shrinkage,': [236, 500, 2723, 5145, 6380], 'but': [237, 501, 1661, 2938, 4082, 5360, 6596], 'hyperosmolality,': [240, 504], 'triggers': [241, 505], 'response': [251, 515, 636, 797, 1786, 2701, 2729, 3055, 3217, 4208, 5123, 5151, 5438, 6357, 6386], 'hypertonicity;': [254, 518], '2)': [256, 520, 1098, 1734, 2216, 3518, 4155, 4638, 5870], 'dependent': [259, 523], 'on': [260, 524, 837, 1722, 3257, 4143], 'activation.': [263, 527], '[4-(2-aminoethyl)-benzenesulfonylfluoride)]': [534], 'bovine': [535], 'serum': [536], 'albumin': [537], 'polyacrylamide': [544], 'gel': [545], 'electrophoresis': [546], 'Tris-buffered': [550], 'saline': [551], 'During': [557, 2976], 'diuresis': [558, 2036, 2977, 4458, 5689], 'antidiuresis,': [560, 2038, 2979, 4460, 5691], 'large': [567, 2986], 'fluctuations': [568, 2987], '(1Knepper': [572, 2040, 2991, 4462, 5693], 'M.A.': [573, 2041, 2992, 4463, 5694], 'Rector': [574, 2042, 2993, 4464, 5695], 'Jr.,': [575, 2043, 2994, 4465, 5696], 'F.C.': [576, 2044, 2995, 4466, 5697], 'Brenner': [577, 2045, 2996, 4467, 5698], 'B.M.': [578, 2046, 2997, 4468, 5699], 'Kidney.': [580, 2048, 2999, 4470, 5701], '5th': [581, 2049, 3000, 4471, 5702], 'Ed.': [582, 2050, 3001, 4472, 5703], 'W.': [583, 2051, 3002, 4473, 5704], 'B.': [584, 1057, 1156, 1535, 2052, 3003, 3477, 3576, 3956, 4474, 5705], 'Saunders': [585, 2053, 3004, 4475, 5706], 'Co.,': [586, 2054, 3005, 4476, 5707], 'Philadelphia1996:': [587, 2055, 3006, 4477, 5708], '532-570Google': [588, 2056, 3007, 4478, 5709], 'Scholar),': [589, 1635, 1660, 1823, 2014, 2170, 2598, 3008, 4056, 4081, 4245, 4436, 4592, 5020, 5476, 5667, 5823, 6254], 'which': [590, 658, 828, 1310, 2023, 2205, 2219, 2288, 2398, 3009, 3077, 3248, 3730, 4445, 4627, 4641, 4710, 4820, 5676, 5859, 5873, 5942, 6053], 'challenge': [591, 2803, 3010, 5225, 6460], 'constancy.': [594, 3013], 'Cells': [595, 3014], '(MTAL)1': [604, 3023], 'special': [607, 3026], 'interest,': [608, 3027], 'since': [609, 2077, 3028, 4499, 5730], 'they': [610, 3029], 'major': [613, 869, 1779, 2184, 3032, 3289, 4201, 4606, 5431, 5838], 'contributor': [614, 3033], 'generation': [617, 3036], 'renal': [620, 2151, 3039, 4573, 5804], 'cortico-papillary': [621, 3040], 'osmotic': [622, 2717, 3041, 5139, 6374], 'gradient': [623, 3042], 'allowing': [624, 3043], 'urinary': [625, 3044], 'concentration': [626, 2395, 3045, 4817, 6050], 'terrestrial': [628, 3047], 'animals.': [629, 3048], 'first': [631, 3050], 'adaptive': [632, 711, 774, 3051, 3130, 3193], 'process': [633, 2759, 3052, 5181, 6416], 'occurring': [634, 3053], 'hypertonicity-induced': [639, 2192, 3058, 4614, 5846], '(RVI).': [648, 3067], 'results': [651, 1766, 1993, 2299, 2793, 3070, 4188, 4415, 4721, 5215, 5418, 5646, 5953, 6450], 'from': [652, 672, 745, 2029, 3071, 3091, 3164, 4451, 5682], 'stimulation': [654, 1467, 2647, 3073, 3887, 5069, 6303], 'ion': [656, 662, 2735, 2854, 3075, 3081, 5157, 5276, 6392, 6511], 'transporters': [657, 2736, 2855, 3076, 5158, 5277, 6393, 6512], 'content': [663, 3082], 'within': [664, 731, 3083, 3150], 'minutes': [665, 3084], 'partially': [667, 3086], 'restore': [668, 3087], '(2Parker': [677, 2406, 2781, 3096, 4828, 5203, 6061, 6438], 'J.C.': [678, 2407, 2782, 3097, 4829, 5204, 6062, 6439], 'Am.': [679, 759, 1610, 1628, 1653, 1958, 2007, 2125, 2408, 2546, 2591, 2783, 3098, 3178, 4031, 4049, 4074, 4380, 4429, 4547, 4830, 4968, 5013, 5205, 5611, 5660, 5778, 6063, 6201, 6247, 6440], 'J.': [680, 760, 898, 957, 989, 1020, 1021, 1062, 1136, 1138, 1180, 1206, 1326, 1351, 1379, 1412, 1422, 1423, 1448, 1485, 1563, 1594, 1611, 1629, 1654, 1841, 1872, 1888, 1898, 1936, 1959, 1972, 2008, 2126, 2160, 2340, 2409, 2474, 2501, 2506, 2547, 2592, 2784, 2880, 2890, 2891, 3099, 3179, 3318, 3377, 3409, 3440, 3441, 3482, 3556, 3558, 3600, 3626, 3746, 3771, 3799, 3832, 3842, 3843, 3868, 3905, 3984, 4015, 4032, 4050, 4075, 4263, 4294, 4310, 4320, 4358, 4381, 4394, 4430, 4548, 4582, 4762, 4831, 4896, 4923, 4928, 4969, 5014, 5206, 5302, 5312, 5313, 5494, 5525, 5541, 5551, 5589, 5612, 5625, 5661, 5779, 5813, 5994, 6064, 6129, 6156, 6161, 6202, 6248, 6441, 6537, 6547, 6548], 'Physiol.': [681, 761, 850, 1266, 1612, 1630, 1655, 1814, 1960, 2009, 2092, 2127, 2410, 2548, 2593, 2785, 3100, 3180, 3270, 3686, 4033, 4051, 4076, 4236, 4382, 4431, 4514, 4549, 4832, 4970, 5015, 5207, 5467, 5613, 5662, 5745, 5780, 6065, 6203, 6249, 6442], '1993;': [682, 910, 939, 2411, 2786, 3101, 3330, 3359, 4833, 5208, 6066, 6443], '265:': [683, 1542, 2412, 2787, 3102, 3963, 4834, 5209, 6067, 6444], 'C1191-C1200Crossref': [684, 2413, 2788, 3103, 4835, 5210, 6068, 6445], 'PubMed': [685, 704, 765, 855, 913, 942, 966, 1000, 1032, 1049, 1073, 1120, 1146, 1165, 1191, 1217, 1230, 1271, 1287, 1337, 1357, 1390, 1429, 1459, 1496, 1528, 1544, 1569, 1603, 1819, 1847, 1881, 1909, 1945, 1983, 2097, 2166, 2351, 2414, 2451, 2485, 2517, 2753, 2789, 2820, 2897, 3104, 3123, 3184, 3275, 3333, 3362, 3386, 3420, 3452, 3469, 3493, 3540, 3566, 3585, 3611, 3637, 3650, 3691, 3707, 3757, 3777, 3810, 3849, 3879, 3916, 3949, 3965, 3990, 4024, 4241, 4269, 4303, 4331, 4367, 4405, 4519, 4588, 4773, 4836, 4873, 4907, 4939, 5175, 5211, 5242, 5319, 5472, 5500, 5534, 5562, 5598, 5636, 5750, 5819, 6005, 6069, 6106, 6140, 6172, 6410, 6446, 6477, 6554], 'Google': [686, 707, 766, 858, 916, 945, 967, 1003, 1035, 1052, 1076, 1123, 1149, 1168, 1194, 1220, 1233, 1274, 1290, 1340, 1360, 1393, 1432, 1462, 1499, 1531, 1547, 1572, 1604, 1616, 1634, 1659, 1822, 1850, 1882, 1912, 1946, 1964, 1986, 2013, 2100, 2131, 2169, 2354, 2415, 2454, 2488, 2520, 2552, 2597, 2756, 2790, 2823, 2900, 3105, 3126, 3185, 3278, 3336, 3365, 3387, 3423, 3455, 3472, 3496, 3543, 3569, 3588, 3614, 3640, 3653, 3694, 3710, 3760, 3780, 3813, 3852, 3882, 3919, 3952, 3968, 3993, 4025, 4037, 4055, 4080, 4244, 4272, 4304, 4334, 4368, 4386, 4408, 4435, 4522, 4553, 4591, 4776, 4837, 4876, 4910, 4942, 4974, 5019, 5178, 5212, 5245, 5322, 5475, 5503, 5535, 5565, 5599, 5617, 5639, 5666, 5753, 5784, 5822, 6008, 6070, 6109, 6143, 6175, 6207, 6253, 6413, 6447, 6480, 6557], 'Scholar,': [687, 917, 946, 968, 1004, 1036, 1053, 1124, 1150, 1169, 1195, 1221, 1275, 1341, 1433, 1548, 1573, 1605, 1617, 1851, 1883, 1947, 1965, 3106, 3337, 3366, 3388, 3424, 3456, 3473, 3544, 3570, 3589, 3615, 3641, 3695, 3761, 3853, 3969, 3994, 4026, 4038, 4273, 4305, 4369, 4387, 5504, 5536, 5600, 5618], '3Sun': [688, 3107], 'A.M.': [689, 2738, 2805, 3108, 5160, 5227, 6395, 6462], 'Saltzberg': [690, 2739, 2806, 3109, 5161, 5228, 6396, 6463], 'S.N.': [691, 2740, 2807, 3110, 5162, 5229, 6397, 6464], 'Kikeri': [692, 2741, 2808, 3111, 5163, 5230, 6398, 6465], 'D.': [693, 1201, 1885, 1897, 1967, 2742, 2809, 3112, 3621, 4307, 4319, 4389, 5164, 5231, 5538, 5550, 5620, 6399, 6466], 'Hebert': [694, 2743, 2810, 3113, 5165, 5232, 6400, 6467], 'S.C.': [695, 2744, 2811, 3114, 5166, 5233, 6401, 6468], 'Kidney': [696, 2745, 2812, 3115, 5167, 5234, 6402, 6469], 'Int.': [697, 2746, 2813, 3116, 5168, 5235, 6403, 6470], '1990;': [698, 2747, 2814, 3117, 5169, 5236, 6404, 6471], '38:': [699, 2748, 2815, 3118, 5170, 5237, 6405, 6472], '1019-1029Abstract': [700, 2749, 2816, 3119, 5171, 5238, 6406, 6473], 'Full': [701, 963, 995, 997, 1027, 1029, 1068, 1070, 1143, 1186, 1188, 1212, 1214, 1332, 1334, 1385, 1387, 1454, 1456, 1491, 1493, 1600, 1878, 1904, 1906, 1942, 1978, 1980, 2346, 2348, 2480, 2482, 2512, 2514, 2750, 2817, 3120, 3383, 3415, 3417, 3447, 3449, 3488, 3490, 3563, 3606, 3608, 3632, 3634, 3752, 3754, 3805, 3807, 3874, 3876, 3911, 3913, 4021, 4300, 4326, 4328, 4364, 4400, 4402, 4768, 4770, 4902, 4904, 4934, 4936, 5172, 5239, 5531, 5557, 5559, 5595, 5631, 5633, 6000, 6002, 6135, 6137, 6167, 6169, 6407, 6474], 'Text': [702, 964, 996, 998, 1028, 1030, 1069, 1071, 1144, 1187, 1189, 1213, 1215, 1333, 1335, 1386, 1388, 1455, 1457, 1492, 1494, 1601, 1879, 1905, 1907, 1943, 1979, 1981, 2347, 2349, 2481, 2483, 2513, 2515, 2751, 2818, 3121, 3384, 3416, 3418, 3448, 3450, 3489, 3491, 3564, 3607, 3609, 3633, 3635, 3753, 3755, 3806, 3808, 3875, 3877, 3912, 3914, 4022, 4301, 4327, 4329, 4365, 4401, 4403, 4769, 4771, 4903, 4905, 4935, 4937, 5173, 5240, 5532, 5558, 5560, 5596, 5632, 5634, 6001, 6003, 6136, 6138, 6168, 6170, 6408, 6475], 'PDF': [703, 965, 999, 1031, 1072, 1145, 1190, 1216, 1336, 1389, 1458, 1495, 1602, 1880, 1908, 1944, 1982, 2350, 2484, 2516, 2752, 2819, 3122, 3385, 3419, 3451, 3492, 3565, 3610, 3636, 3756, 3809, 3878, 3915, 4023, 4302, 4330, 4366, 4404, 4772, 4906, 4938, 5174, 5241, 5533, 5561, 5597, 5635, 6004, 6139, 6171, 6409, 6476], 'Scopus': [705, 856, 914, 943, 1001, 1033, 1050, 1074, 1121, 1147, 1166, 1192, 1218, 1231, 1272, 1288, 1338, 1358, 1391, 1430, 1460, 1497, 1529, 1545, 1570, 1820, 1848, 1910, 1984, 2098, 2167, 2352, 2452, 2486, 2518, 2754, 2821, 2898, 3124, 3276, 3334, 3363, 3421, 3453, 3470, 3494, 3541, 3567, 3586, 3612, 3638, 3651, 3692, 3708, 3758, 3778, 3811, 3850, 3880, 3917, 3950, 3966, 3991, 4242, 4270, 4332, 4406, 4520, 4589, 4774, 4874, 4908, 4940, 5176, 5243, 5320, 5473, 5501, 5563, 5637, 5751, 5820, 6006, 6107, 6141, 6173, 6411, 6478, 6555], '(28)': [706, 2755, 2822, 3125, 5177, 5244, 6412, 6479], 'Scholar).': [708, 767, 859, 1234, 1291, 1361, 1394, 1987, 2057, 2132, 2416, 2455, 2757, 2791, 3127, 3186, 3279, 3654, 3711, 3781, 3814, 3920, 4409, 4479, 4554, 4838, 4877, 5179, 5213, 5640, 5710, 5785, 6009, 6071, 6110, 6208, 6414, 6448, 6558], 'A': [709, 2313, 3128, 4735, 5967], 'second': [710, 3129], 'mechanism,': [712, 3131], 'mammalian': [714, 861, 1919, 3133, 3281, 4341, 5572], 'cells,': [715, 862, 2022, 2605, 2685, 2910, 3134, 3282, 4444, 5027, 5107, 5332, 5675, 6261, 6341, 6568], 'induction': [718, 3137], 'genes': [720, 3139], 'encoding': [721, 3140], 'proteins': [722, 737, 2463, 3141, 3156, 4885, 6118], 'involved': [723, 1367, 3142, 3787], 'accumulation': [726, 3145], '“compatible': [729, 3148], 'osmolytes”': [730, 3149], 'hours': [732, 3151], 'days.': [734, 3153], 'These': [735, 2298, 3154, 4720, 5952], 'osmoprotective': [736, 3155], 'either': [739, 3158], 'enzymes,i.e.': [740, 3159], 'aldose': [741, 3160], 'reductase': [742, 3161], 'generating': [743, 3162], 'sorbitol': [744, 3163], 'glucose,': [746, 3165], 'organic': [748, 3167], 'osmolytes': [749, 3168], 'transporters,': [750, 3169], 'i.e.': [751, 1790, 3170, 4212, 5442], 'myo-inositol,': [752, 3171], 'taurine,': [753, 3172], 'glycerophosphocholine,': [754, 3173], 'betaine': [756, 3175], '(4Burg': [757, 3176], 'M.B.': [758, 847, 1263, 1811, 1971, 2089, 3177, 3267, 3683, 4233, 4393, 4511, 5464, 5624, 5742], '1995;': [762, 992, 1024, 1183, 1329, 1354, 3181, 3412, 3444, 3603, 3749, 3774], '268:': [763, 3182], 'F983-F996Crossref': [764, 3183], 'signaling': [770, 2324, 3189, 4746, 5978], 'pathways': [771, 794, 2325, 3190, 3214, 4747, 5979], 'mediating': [772, 3191], 'these': [773, 3192], 'mechanisms,': [775, 3194], 'especially': [776, 3195], 'role': [778, 1677, 1780, 2185, 2314, 2402, 2873, 3197, 4098, 4202, 4607, 4736, 4824, 5295, 5432, 5839, 5968, 6057, 6530], 'MAP': [780, 802, 825, 831, 864, 1240, 1296, 1506, 1687, 1697, 1726, 1740, 1758, 1771, 1799, 2067, 2080, 2111, 2146, 2179, 2193, 2214, 2307, 2358, 2436, 2570, 2663, 2694, 3199, 3222, 3245, 3251, 3284, 3660, 3716, 3927, 4108, 4118, 4147, 4161, 4180, 4193, 4221, 4489, 4502, 4533, 4568, 4601, 4615, 4636, 4729, 4780, 4858, 4992, 5085, 5116, 5410, 5423, 5452, 5720, 5733, 5764, 5799, 5832, 5847, 5868, 5961, 6013, 6091, 6226, 6319, 6350], 'kinases,': [781, 1772, 3200, 4194, 5424], 'still': [783, 3202], 'incompletely': [784, 3203], 'understood.Mitogen-activated': [785], '(MAP)': [787, 3207], 'cascades': [789, 3209], 'important': [791, 3211], 'signal-transduction': [793, 3213], 'changes': [799, 2361, 3219, 4783, 6016], 'osmolality.': [801, 3221], 'serine/threonine': [805, 3225], 'via': [808, 833, 1252, 2440, 3228, 3253, 3672, 4862, 6095], 'cascade': [810, 3230], 'involving': [813, 3233], 'sequential': [815, 2691, 3235, 5113, 6347], 'two': [818, 3238], '(MAP': [820, 3240], 'kinase),': [827, 3247], 'activates': [829, 1757, 2145, 2305, 2357, 2853, 2914, 3249, 4179, 4567, 4727, 4779, 5275, 5336, 5409, 5798, 5959, 6012, 6510, 6572], 'dual': [835, 3255], 'threonine': [838, 3258], 'tyrosine': [840, 2459, 2531, 3260, 4881, 4953, 6114, 6186], 'residues': [841, 3261], '(5Widmann': [842, 1258, 1806, 2084, 3262, 3678, 4228, 4506, 5459, 5737], 'C.': [843, 952, 1223, 1259, 1521, 1807, 1931, 2085, 2444, 3263, 3372, 3643, 3679, 3942, 4229, 4353, 4507, 4866, 5460, 5584, 5738, 6099], 'Gibson': [844, 1260, 1808, 2086, 3264, 3680, 4230, 4508, 5461, 5739], 'S.': [845, 937, 1134, 1171, 1261, 1416, 1447, 1591, 1809, 1869, 1969, 2087, 2339, 2473, 2503, 2884, 3265, 3357, 3554, 3591, 3681, 3836, 3867, 4012, 4231, 4291, 4391, 4509, 4761, 4895, 4925, 5306, 5462, 5522, 5622, 5740, 5993, 6128, 6158, 6541, 6637], 'Jarpe': [846, 1262, 1810, 2088, 3266, 3682, 4232, 4510, 5463, 5741], 'Johnson': [848, 1264, 1812, 2090, 3268, 3684, 4234, 4512, 5465, 5743], 'G.L.': [849, 1265, 1813, 2091, 3269, 3685, 4235, 4513, 5466, 5744], 'Rev.': [851, 1267, 1815, 2093, 3271, 3687, 4237, 4515, 5468, 5746], '1999;': [852, 1268, 1382, 1451, 1488, 1816, 2094, 2509, 3272, 3688, 3802, 3871, 3908, 4238, 4516, 4931, 5469, 5747, 6164], '79:': [853, 1269, 1817, 2095, 3273, 3689, 4239, 4517, 5470, 5748], '143-180Crossref': [854, 1270, 1818, 2096, 3274, 3690, 4240, 4518, 5471, 5749], '(2249)': [857, 1273, 1821, 2099, 3277, 3693, 4243, 4521, 5474, 5752], 'family': [866, 3286], 'contains': [867, 3287], 'three': [868, 1503, 3288, 3924], 'subgroups': [870, 3290], 'responding': [871, 3291], 'distinct': [873, 3293], 'stimuli:': [875, 3295], '1': [879, 3299], '2': [881, 3301], 'principally': [883, 3303], 'growth': [886, 1407, 2420, 3306, 3827, 4842, 6075], 'factors,': [887, 3307], 'integrin-matrix': [888, 3308], 'interaction,': [889, 3309], 'hormones': [891, 3311], 'neurotransmitters': [893, 3313], 'serpentine': [895, 3315], 'receptors': [896, 2424, 3316, 4846, 6079], '(6Wu': [897, 3317], 'Dent': [899, 3319], 'P.': [900, 1010, 1038, 3320, 3430, 3458], 'Jelinek': [901, 3321], 'T.': [902, 956, 972, 984, 1110, 1154, 1175, 1277, 1435, 1478, 1550, 1558, 1583, 1585, 1619, 1828, 1836, 1861, 1863, 1935, 1949, 2159, 3322, 3376, 3392, 3404, 3530, 3574, 3595, 3697, 3855, 3898, 3971, 3979, 4004, 4006, 4040, 4250, 4258, 4283, 4285, 4357, 4371, 4581, 5481, 5489, 5514, 5516, 5588, 5602, 5812], 'Wolfman': [903, 3323], 'A.': [904, 938, 1480, 1482, 1484, 1552, 1554, 1830, 1832, 2497, 3324, 3358, 3900, 3902, 3904, 3973, 3975, 4252, 4254, 4919, 5483, 5485, 6152], 'Weber': [905, 3325], 'M.J.': [906, 3326], 'Sturgill': [907, 3327], 'T.W.': [908, 3328], 'Science.': [909, 1226, 1524, 1540, 2447, 3329, 3646, 3945, 3961, 4869, 6102], '262:': [911, 3331], '1065-1072Crossref': [912, 3332], '(817)': [915, 3335], '7Graves': [918, 3338], 'L.M.': [919, 1625, 1955, 3339, 4046, 4377, 5608], 'Bornfeldt': [920, 3340], 'K.E.': [921, 3341], 'Raines': [922, 3342], 'E.W.': [923, 3343], 'Potts': [924, 3344], 'B.C.': [925, 1061, 3345, 3481], 'MacDonald': [926, 3346], 'S.G.': [927, 3347], 'Ross': [928, 3348], 'R.': [929, 1321, 1323, 1476, 1892, 3349, 3741, 3743, 3896, 4314, 5545], 'Krebs': [930, 1324, 1588, 1866, 3350, 3744, 4009, 4288, 5519], 'E.G.': [931, 1325, 1589, 1867, 3351, 3745, 4010, 4289, 5520], 'Proc.': [932, 3352], 'Natl.': [933, 3353], 'Acad.': [934, 3354], 'Sci.': [935, 3355], 'U.': [936, 3356], '90:': [940, 3360], '10300-10304Crossref': [941, 3361], '(400)': [944, 3364], '8Ferby': [947, 3367], 'I.M.': [948, 1927, 3368, 4349, 5580], 'Waga': [949, 1928, 3369, 4350, 5581], 'I.': [950, 1929, 3370, 4351, 5582], 'Sakanaka': [951, 1930, 3371, 4352, 5583], 'Kume': [953, 1932, 3373, 4354, 5585], 'K.': [954, 974, 976, 978, 980, 982, 1437, 1439, 1556, 1577, 1834, 1855, 1933, 2337, 2471, 2499, 3374, 3394, 3396, 3398, 3400, 3402, 3857, 3859, 3977, 3998, 4256, 4277, 4355, 4759, 4893, 4921, 5487, 5508, 5586, 5991, 6126, 6154], 'Shimizu': [955, 1934, 3375, 4356, 5587], 'Biol.': [958, 990, 1022, 1063, 1116, 1161, 1181, 1207, 1283, 1327, 1352, 1380, 1425, 1449, 1486, 1595, 1873, 1899, 1937, 1973, 2341, 2475, 2507, 2893, 3378, 3410, 3442, 3483, 3536, 3581, 3601, 3627, 3703, 3747, 3772, 3800, 3845, 3869, 3906, 4016, 4295, 4321, 4359, 4395, 4763, 4897, 4929, 5315, 5526, 5552, 5590, 5626, 5995, 6130, 6162, 6550], 'Chem.': [959, 991, 1023, 1064, 1182, 1208, 1328, 1353, 1381, 1450, 1487, 1596, 1874, 1900, 1938, 1974, 2342, 2476, 2508, 3379, 3411, 3443, 3484, 3602, 3628, 3748, 3773, 3801, 3870, 3907, 4017, 4296, 4322, 4360, 4396, 4764, 4898, 4930, 5527, 5553, 5591, 5627, 5996, 6131, 6163], '1994;': [960, 1046, 1140, 1162, 1541, 1566, 1597, 1844, 1875, 1939, 3380, 3466, 3560, 3582, 3962, 3987, 4018, 4266, 4297, 4361, 5497, 5528, 5592], '269:': [961, 1598, 1876, 1940, 3381, 4019, 4298, 4362, 5529, 5593], '30485-30488Abstract': [962, 1941, 3382, 4363, 5594], '9Morino': [969, 3389], 'N.': [970, 1040, 1059, 1560, 1838, 3390, 3460, 3479, 3981, 4260, 5491], 'Mimura': [971, 3391], 'Hamasaki': [973, 3393], 'Tobe': [975, 3395], 'Ueki': [977, 3397], 'Kikuchi': [979, 3399], 'Takehara': [981, 3401], 'Kadowaki': [983, 3403], 'Yazaki': [985, 3405], 'Y.': [986, 988, 1177, 1346, 1445, 1562, 1575, 1587, 1840, 1853, 1865, 3406, 3408, 3597, 3766, 3865, 3983, 3996, 4008, 4262, 4275, 4287, 5493, 5506, 5518], 'Nojima': [987, 3407], '270:': [993, 1025, 1184, 1330, 1355, 3413, 3445, 3604, 3750, 3775], '269-273Abstract': [994, 3414], '(261)': [1002, 3422], '10Flordellis': [1005, 3425], 'C.S.': [1006, 3426], 'Berguerand': [1007, 3427], 'M.': [1008, 1225, 1441, 1523, 2446, 3428, 3645, 3861, 3944, 4868, 6101], 'Gouache': [1009, 3429], 'Barbu': [1011, 3431], 'V.': [1012, 3432], 'Gavras': [1013, 3433], 'H.': [1014, 1173, 1319, 1376, 1443, 1581, 1859, 3434, 3593, 3739, 3796, 3863, 4002, 4281, 5512], 'Handy': [1015, 3435], 'D.E.': [1016, 1350, 3436, 3770], 'Béréziat': [1017, 3437], 'G.': [1018, 1474, 1621, 1951, 3438, 3894, 4042, 4373, 5604], 'Masliah': [1019, 3439], '3491-3494Abstract': [1026, 3446], '(52)': [1034, 3454], '11Crespo': [1037, 3457], 'Xu': [1039, 3459], 'Simmonds': [1041, 3461], 'W.S.': [1042, 3462], 'Gutkind': [1043, 3463], 'J.S.': [1044, 3464], 'Nature.': [1045, 3465], '369:': [1047, 3467], '418-420Crossref': [1048, 3468], '(758)': [1051, 3471], '12Liao': [1054, 3474], 'D.-F.': [1055, 3475], 'Monia': [1056, 3476], 'Dean': [1058, 3478], 'Berk': [1060, 3480], '1997;': [1065, 1631, 1961, 2343, 2477, 3485, 4052, 4383, 4765, 4899, 5614, 5997, 6132], '272:': [1066, 1632, 1962, 2344, 2478, 3486, 4053, 4384, 4766, 4900, 5615, 5998, 6133], '6146-6150Abstract': [1067, 3487], '(206)': [1075, 3495], 'Scholar);': [1077, 3497], '(JNK,': [1081, 3501], 'also': [1082, 3502], 'known': [1083, 1093, 3503, 3513], 'as': [1084, 1094, 1636, 1638, 2071, 2678, 3504, 3514, 4057, 4059, 4493, 5100, 5724, 6334], 'stress-activated': [1085, 1095, 3505, 3515], '1);': [1088, 3508], '(also': [1092, 3512], 'strongly': [1099, 2300, 3519, 4722, 5954], 'inflammatory': [1102, 3522], 'cytokines,': [1103, 3523], 'ultraviolet': [1104, 3524], 'light,': [1105, 3525], 'stress': [1108, 3528], '(13Ip': [1109, 3529], 'Davis': [1111, 1157, 1202, 1278, 1538, 1649, 2003, 2121, 2542, 2587, 3531, 3577, 3622, 3698, 3959, 4070, 4425, 4543, 4964, 5009, 5656, 5774, 6197, 6243], 'R.J.': [1112, 1158, 1203, 1279, 1539, 1650, 2004, 2122, 2543, 2588, 3532, 3578, 3623, 3699, 3960, 4071, 4426, 4544, 4965, 5010, 5657, 5775, 6198, 6244], 'Curr.': [1113, 1280, 3533, 3700], 'Opin.': [1114, 1281, 3534, 3701], 'Cell': [1115, 1282, 1424, 2892, 3535, 3702, 3844, 5314, 6549], '1998;': [1117, 1284, 1426, 1656, 1901, 1975, 2010, 2128, 2163, 2549, 2594, 2894, 3537, 3704, 3846, 4077, 4323, 4397, 4432, 4550, 4585, 4971, 5016, 5316, 5554, 5628, 5663, 5781, 5816, 6204, 6250, 6551], '10:': [1118, 1285, 3538, 3705], '205-219Crossref': [1119, 1286, 3539, 3706], '(1374)': [1122, 1289, 3542, 3709], '14Freshney': [1125, 3545], 'N.W.': [1126, 3546], 'Rawlinson': [1127, 3547], 'L.': [1128, 1623, 1953, 3548, 4044, 4375, 5606], 'Guesdon': [1129, 3549], 'F.': [1130, 1414, 1593, 1871, 2882, 3550, 3834, 4014, 4293, 5304, 5524, 6539], 'Jones': [1131, 3551], 'E.': [1132, 1179, 2335, 2469, 3552, 3599, 4757, 4891, 5989, 6124], 'Cowley': [1133, 3553], 'Hsuan': [1135, 3555], 'Saklatvala': [1137, 3557], 'Cell.': [1139, 1160, 3559, 3580], '78:': [1141, 3561], '1039-1049Abstract': [1142, 3562], '(774)': [1148, 3568], '15Sluss': [1151, 3571], 'H.K.': [1152, 3572], 'Barrett': [1153, 3573], 'Dérijard': [1155, 1534, 3575, 3955], 'Mol.': [1159, 3579], '14:': [1163, 3583], '8376-8384Crossref': [1164, 3584], '(444)': [1167, 3587], '16Matsuda': [1170, 3590], 'Kawasaki': [1172, 3592], 'Moriguchi': [1174, 3594], 'Gotoh': [1176, 3596], 'Nishida': [1178, 3598], '12781-12786Abstract': [1185, 3605], '(149)': [1193, 1461, 3613, 3881], '17Chen': [1196, 3616], 'Y.-R.': [1197, 3617], 'Wang': [1198, 3618], 'X.': [1199, 3619], 'Templeton': [1200, 3620], 'Tan': [1204, 3624], 'T.-H.': [1205, 3625], '1996;': [1209, 1227, 1525, 1613, 2448, 3629, 3647, 3946, 4034, 4870, 6103], '271:': [1210, 1614, 3630, 4035], '31929-31936Abstract': [1211, 3631], '(854)': [1219, 3639], '18Rosette': [1222, 3642], 'Karin': [1224, 1522, 2445, 3644, 3943, 4867, 6100], '274:': [1228, 1383, 1452, 1489, 1526, 2449, 2510, 3648, 3803, 3872, 3909, 3947, 4871, 4932, 6104, 6165], '1194-1197Crossref': [1229, 1527, 2450, 3649, 3948, 4872, 6105], '(941)': [1232, 1530, 2453, 3652, 3951, 4875, 6108], 'To': [1235, 3655], 'date,': [1236, 3656], 'effects': [1238, 1294, 1718, 3658, 3714, 4139], 'have': [1242, 1706, 1710, 2904, 3662, 4127, 4131, 5326, 6562], 'been': [1243, 1512, 1707, 1795, 2328, 3663, 3933, 4128, 4217, 4750, 5448, 5982], 'mostly': [1244, 3664], 'attributed': [1245, 3665], 'control': [1248, 1303, 1370, 3668, 3723, 3790], 'gene': [1250, 3670], 'transcription': [1251, 1256, 3671, 3676], 'nuclear': [1255, 3675], 'factors': [1257, 3677], '13Ip': [1276, 3696], 'non-genomic': [1293, 3713], 'increasingly': [1299, 3719], 'recognized.': [1300, 3720], 'ERKs': [1301, 1364, 3721, 3784], 'may': [1302, 2372, 2688, 3722, 4794, 5110, 6027, 6344], 'glucose': [1304, 1469, 3724, 3889], 'metabolism': [1305, 3725], 'through': [1306, 2360, 2856, 3726, 4782, 5278, 6015, 6513], 'p90rsk,': [1309, 3729], 'phosphorylates': [1311, 3731], 'inhibits': [1313, 3733], 'glycogen': [1314, 3734], 'synthase': [1315, 3735], '3': [1317, 3737], '(19Eldar-Finkelman': [1318, 3738], 'Seger': [1320, 3740], 'Vandenheede': [1322, 3742], '987-990Abstract': [1331, 3751], '(192)': [1339, 3759], '20Chang': [1342, 3762], 'P.-Y.': [1343, 3763], 'Le': [1344, 3764], 'Marchand-Brustel': [1345, 3765], 'Cheatham': [1347, 3767], 'L.A.': [1348, 3768], 'Moller': [1349, 3769], '29928-29935Crossref': [1356, 3776], '(44)': [1359, 3779], 'addition,': [1363, 1764, 2945, 3783, 4186, 5367, 5416, 6603], 'might': [1365, 1401, 2665, 3785, 3821, 5087, 6321], 'cAMP-specific': [1372, 3792], 'phosphodiesterase': [1373, 3793], 'activity': [1374, 2109, 3794, 4531, 5762], '(21Liu': [1375, 3795], 'Maurice': [1377, 3797], 'D.H.': [1378, 3798], '10557-10565Abstract': [1384, 3804], '(81)': [1392, 3812], 'On': [1395, 3815], 'other': [1397, 3817], 'hand,': [1398, 3818], 'implicated': [1403, 3823], 'stress-': [1405, 3825], 'factor-induced': [1408, 3828], 'cytoskeleton': [1409, 2371, 3829, 4793, 6026], 'reorganization': [1410, 3830], '(22Huot': [1411, 2879, 3831, 5301, 6536], 'Houle': [1413, 2881, 3833, 5303, 6538], 'Rousseau': [1415, 2883, 3835, 5305, 6540], 'Deschesnes': [1417, 2885, 3837, 5307, 6542], 'R.G.': [1418, 2886, 3838, 5308, 6543], 'Shah': [1419, 2887, 3839, 5309, 6544], 'G.M.': [1420, 2888, 3840, 5310, 6545], 'Landry': [1421, 2889, 3841, 5311, 6546], '143:': [1427, 2895, 3847, 5317, 6552], '1361-1373Crossref': [1428, 2896, 3848, 5318, 6553], '(266)': [1431, 2899, 3851, 5321, 6556], '23Matsumoto': [1434, 3854], 'Yokote': [1436, 3856], 'Tamura': [1438, 3858], 'Takemoto': [1440, 3860], 'Ueno': [1442, 3862], 'Saito': [1444, 3864], 'Mori': [1446, 3866], '13954-13960Abstract': [1453, 3873], 'Scholar)': [1463, 1913, 2101, 2489, 2521, 2824, 3883, 4335, 4523, 4911, 4943, 5246, 5566, 5754, 6144, 6176, 6481], 'transport': [1470, 3890], 'insulin': [1472, 3892], '(24Sweeney': [1473, 3893], 'Somwar': [1475, 3895], 'Ramlal': [1477, 3897], 'Volchuk': [1479, 3899], 'Ueyama': [1481, 3901], 'Klip': [1483, 3903], '10071-10078Abstract': [1490, 3910], '(273)': [1498, 3918], 'Scholar).Activation': [1500], 'families': [1504, 3925], 'has': [1511, 1794, 2326, 3932, 4216, 4748, 5447, 5980], 'shown': [1513, 1796, 2905, 3934, 4218, 5327, 5449, 6563], 'different': [1515, 1720, 3936, 4141], 'lines': [1517, 1805, 3938, 4227, 5458], 'culture': [1519, 3940], '(18Rosette': [1520, 2443, 3941, 4865, 6098], 'Scholar,25Galcheva-Gargova': [1532, 3953], 'Z.': [1533, 1607, 3954, 4028], 'Wu': [1536, 3957], 'I.-H.': [1537, 3958], '806-811Crossref': [1543, 3964], '(529)': [1546, 3967], '26Itoh': [1549, 3970], 'Yamauchi': [1551, 1829, 3972, 4251, 5482], 'Miyai': [1553, 1831, 3974, 4253, 5484], 'Yokoyama': [1555, 1833, 3976, 4255, 5486], 'Kamada': [1557, 1835, 3978, 4257, 5488], 'Ueda': [1559, 1837, 3980, 4259, 5490], 'Fujiwara': [1561, 1839, 3982, 4261, 5492], 'Clin.': [1564, 1842, 2161, 3985, 4264, 4583, 5495, 5814], 'Invest.': [1565, 1843, 2162, 3986, 4265, 4584, 5496, 5815], '93:': [1567, 1845, 3988, 4267, 5498], '2387-2392Crossref': [1568, 1846, 3989, 4268, 5499], '(117)': [1571, 1849, 3992, 4271, 5502], '27Terada': [1574, 1852, 3995, 4274, 5505], 'Tomita': [1576, 1854, 3997, 4276, 5507], 'Homma': [1578, 1856, 3999, 4278, 5509], 'M.K.': [1579, 1857, 4000, 4279, 5510], 'Nonoguchi': [1580, 1858, 4001, 4280, 5511], 'Yang': [1582, 1860, 4003, 4282, 5513], 'Yamada': [1584, 1862, 4005, 4284, 5515], 'Yuasa': [1586, 1864, 4007, 4286, 5517], 'Sasaki': [1590, 1868, 4011, 4290, 5521], 'Marumo': [1592, 1870, 4013, 4292, 5523], '31296-31301Abstract': [1599, 1877, 4020, 4299, 5530], '28Zhang': [1606, 4027], 'Cohen': [1608, 4029], 'D.M.': [1609, 4030], 'F1234-F1238PubMed': [1615, 4036], '29Berl': [1618, 1948, 4039, 4370, 5601], 'Siriwardana': [1620, 1950, 4041, 4372, 5603], 'Ao': [1622, 1952, 4043, 4374, 5605], 'Butterfield': [1624, 1954, 4045, 4376, 5607], 'Heasley': [1626, 1956, 2156, 4047, 4378, 4578, 5609, 5809], 'L.E.': [1627, 1957, 2157, 4048, 4379, 4579, 5610, 5810], 'F305-F311PubMed': [1633, 1963, 4054, 4385, 5616], 'well': [1637, 4058], 'native': [1640, 2019, 4061, 4441, 5672], 'cells': [1643, 1730, 1826, 1922, 1925, 2115, 2333, 2388, 2467, 2495, 2536, 2558, 2626, 2725, 2770, 2797, 4064, 4151, 4248, 4344, 4347, 4537, 4755, 4810, 4889, 4917, 4958, 4980, 5048, 5147, 5192, 5219, 5479, 5575, 5578, 5768, 5987, 6043, 6122, 6150, 6191, 6214, 6282, 6382, 6427, 6454], '(30Watts': [1644, 1998, 2116, 2537, 2582, 4065, 4420, 4538, 4959, 5004, 5651, 5769, 6192, 6238], 'B.A.I.': [1645, 1999, 2117, 2538, 2583, 4066, 4421, 4539, 4960, 5005, 5652, 5770, 6193, 6239], 'Di': [1646, 1886, 2000, 2118, 2539, 2584, 4067, 4308, 4422, 4540, 4961, 5006, 5539, 5653, 5771, 6194, 6240], 'Mari': [1647, 1887, 2001, 2119, 2540, 2585, 4068, 4309, 4423, 4541, 4962, 5007, 5540, 5654, 5772, 6195, 6241], 'J.F.': [1648, 2002, 2120, 2541, 2586, 4069, 4424, 4542, 4963, 5008, 5655, 5773, 6196, 6242], 'Good': [1651, 2005, 2123, 2544, 2589, 4072, 4427, 4545, 4966, 5011, 5658, 5776, 6199, 6245], 'D.W.': [1652, 2006, 2124, 2545, 2590, 4073, 4428, 4546, 4967, 5012, 5659, 5777, 6200, 6246], '275:': [1657, 2011, 2129, 2550, 2595, 4078, 4433, 4551, 4972, 5017, 5664, 5782, 6205, 6251], 'F478-F486PubMed': [1658, 2012, 2130, 2551, 2596, 4079, 4434, 4552, 4973, 5018, 5665, 5783, 6206, 6252], 'mechanisms': [1663, 4084], 'their': [1665, 2075, 2427, 4086, 4497, 4849, 5728, 6082], 'need': [1670, 4091], 'clarified.': [1673, 4094], 'Neither': [1674, 4095], 'hypertonicityversus': [1680, 4101], 'hyperosmolality': [1691, 4112], 'nor': [1692, 4113], 'relationship': [1694, 1738, 4115, 4159], 'between': [1695, 1739, 4116, 4160], 'We': [1709, 4130, 6634], 'undertaken': [1711, 4132], 'this': [1712, 2016, 2838, 2946, 4133, 4438, 5260, 5368, 5669, 6495, 6604], 'study:': [1713, 4134], 'examine': [1716, 4137], 'solutes': [1721, 4142], 'hypertonicity,': [1732, 1789, 2563, 4153, 4211, 4985, 5441, 6219], 'analyze': [1736, 4157], 'variations.DISCUSSIONThe': [1746], 'present': [1747, 2060, 4169, 4482, 5399, 5713], 'study': [1748, 2140, 2600, 2947, 4170, 4562, 5022, 5369, 5400, 5793, 6256, 6605], 'shows': [1749, 2601, 4171, 5023, 5401, 6257], 'that': [1750, 1914, 2142, 2302, 2367, 2602, 2730, 2795, 2831, 2949, 4172, 4336, 4564, 4724, 4789, 5024, 5152, 5217, 5253, 5371, 5402, 5567, 5795, 5956, 6022, 6258, 6387, 6452, 6488, 6607], 'induced': [1753, 2220, 2674, 4175, 4642, 5096, 5405, 5874, 6330], 'MTAL.': [1762, 4184, 5414], 'our': [1765, 2599, 4187, 5021, 5417, 6255], 'indicate': [1767, 4189, 5419], 'that,': [1768, 2906, 4190, 5328, 5420, 6564], 'among': [1769, 4191, 5421], 'appears': [1775, 4197, 5427], 'play': [1777, 2400, 2847, 4199, 4822, 5269, 5429, 6055, 6504], 'early': [1783, 4205, 5435], 'protective': [1785, 4207, 5437], 'RVI.Extracellular': [1792, 4214], 'various': [1802, 4224, 5455], 'animal': [1803, 4225, 5456], 'including': [1824, 4246, 5477], 'MDCK': [1825, 4247, 5478], '(26Itoh': [1827, 4249, 5480], '31Sheikh-Hamad': [1884, 4306, 5537], 'Suki': [1889, 4311, 5542], 'W.N.': [1890, 4312, 5543], 'Safirstein': [1891, 4313, 5544], 'Watts': [1893, 1995, 2579, 4315, 4417, 5001, 5546, 5648, 6235], 'III.,': [1894, 4316, 5547], 'B.A.': [1895, 4317, 5548], 'Rouse': [1896, 4318, 5549], '273:': [1902, 1976, 4324, 4398, 5555, 5629], '1832-1837Abstract': [1903, 4325, 5556], '(163)': [1911, 4333, 5564], 'share': [1915, 4337, 5568], 'some': [1916, 4338, 5569], 'properties': [1917, 4339, 5570], 'distal': [1920, 4342, 5573], 'nephron': [1921, 4343, 5574], 'mIMCD': [1924, 2625, 4346, 5047, 5577, 6281], '(8Ferby': [1926, 4348, 5579], '32Kültz': [1966, 4388, 5619], 'Madhany': [1968, 4390, 5621], 'Burg': [1970, 4392, 5623], '13645-13651Abstract': [1977, 4399, 5630], '(184)': [1985, 4407, 5638], 'Our': [1988, 2133, 2792, 4410, 4555, 5214, 5641, 5786, 6449], 'study,': [1989, 2061, 4411, 4483, 5642, 5714], 'taken': [1990, 2070, 2135, 4412, 4492, 4557, 5643, 5723, 5788], 'et': [1996, 2580, 4418, 5002, 5649, 6236], 'al.': [1997, 2581, 4419, 5003, 5650, 6237], 'extends': [2015, 4437, 5668], 'finding': [2017, 4439, 5670], 'osmolarities': [2028, 4450, 5681], '300': [2030, 4452, 5683], 'under': [2034, 2275, 4456, 4697, 5687, 5929], 'water': [2035, 2143, 2384, 2766, 4457, 4565, 4806, 5188, 5688, 5796, 6039, 6423], 'respectively': [2039, 4461, 5692], 'an': [2072, 2281, 2391, 2710, 2801, 2933, 4494, 4703, 4813, 5132, 5223, 5355, 5725, 5935, 6046, 6367, 6458, 6591], 'index': [2073, 4495, 5726], 'only': [2078, 4500, 5731], 'phosphorylated': [2079, 4501, 5732], 'active': [2083, 4505, 5736], 'parallels': [2107, 4529, 5760], 'results,': [2134, 4556, 5787], 'together': [2136, 4558, 5789], 'recent': [2139, 4561, 5792], 'showing': [2141, 4563, 5794], 'restriction': [2144, 4566, 5797], 'inner': [2152, 4574, 5805], '(33Wojtaszek': [2154, 4576, 5807], 'P.A.': [2155, 4577, 5808], 'Berl': [2158, 4580, 5811], '102:': [2164, 4586, 5817], '1874-1881Crossref': [2165, 4587, 5818], '(27)': [2168, 4590, 5821], 'support': [2171, 4593, 5824], 'physiological': [2173, 2969, 4595, 5391, 5826, 6627], 'relevance': [2174, 4596, 5827], 'hypertonicity.The': [2183, 4605], 'supported': [2197, 4619, 5851], 'observations.': [2201, 4623, 5855], 'Hypertonic': [2203, 4625, 5857], 'urea,': [2204, 4626, 5858], 'volume,': [2210, 2226, 2364, 4632, 4648, 4786, 5864, 5880, 6019], 'kinases;': [2215, 2254, 4637, 4676, 5869, 5908], 'sucrose,': [2218, 2828, 4640, 5250, 5872, 6485], 'larger': [2222, 4644, 5876], 'decrease': [2223, 4645, 5877], 'more': [2229, 2670, 2699, 4651, 5092, 5121, 5883, 6326, 6355], 'powerful': [2230, 4652, 5884], 'activator': [2231, 4653, 5885], 'than': [2237, 2646, 4659, 5068, 5891, 6302], 'NaCl;': [2239, 4661, 5893], '3)': [2240, 4662, 5894], 'inversely': [2244, 4666, 5898], '4)': [2255, 4677, 5909], 'alteration': [2260, 4682, 5914], 'kinase;': [2270, 4692, 5924], '5)': [2272, 4694, 5926], 'isotonic': [2276, 4698, 5930], 'conditions': [2277, 4699, 5931], 'associated': [2279, 4701, 5933], 'kinase,': [2287, 4709, 5941], 'reversible': [2290, 4712, 5944], 'upon': [2291, 4713, 5945], 'return': [2292, 4714, 5946], 'volume.': [2297, 4719, 5951], 'suggest': [2301, 4723, 5955], 'cells.': [2312, 2639, 4734, 5061, 5966, 6295], 'for': [2315, 2837, 2874, 4737, 5259, 5296, 5969, 6494, 6531, 6639], 'variations': [2318, 4740, 5972], 'regulation': [2321, 4743, 5975], 'already': [2327, 4749, 5981], 'demonstrated': [2329, 4751, 5983], 'human': [2331, 2465, 4753, 4887, 5985, 6120], 'polymorphonuclear': [2332, 2466, 4754, 4888, 5986, 6121], '(34Krump': [2334, 2468, 4756, 4890, 5988, 6123], 'Nikitas': [2336, 2470, 4758, 4892, 5990, 6125], 'Grinstein': [2338, 2472, 4760, 4894, 5992, 6127], '17303-17311Abstract': [2345, 2479, 4767, 4901, 5999, 6134], '(126)': [2353, 2487, 4775, 4909, 6007, 6142], 'Scholar).Since': [2355, 4777], 'hyperosmolarity': [2356, 2970, 4778, 5392, 6011, 6628], 'hypothesis': [2366, 4788, 6021], 'components': [2368, 4790, 6023], 'primary': [2375, 4797, 6030], 'sensor': [2376, 2405, 4798, 4827, 6031, 6060], 'should': [2377, 4799, 6032], 'considered.': [2379, 4801, 6034], 'Moreover,': [2380, 4802, 6035], 'drives': [2383, 2760, 4805, 5182, 6038, 6417], 'movement': [2385, 4807, 6040], 'outside': [2386, 4808, 6041], 'cytoplasmic': [2394, 4816, 6049], 'macromolecules,': [2397, 4819, 6052], 'could': [2399, 2430, 4821, 4852, 6054, 6085], 'Finally,': [2417, 4839, 6072], 'aggregation': [2418, 4840, 6073], 'factor': [2421, 4843, 6076], 'cytokine': [2423, 4845, 6078], 'ligand-independent': [2428, 4850, 6083], 'participate': [2431, 4853, 6086], 'membrane-based': [2441, 4863, 6096], 'sensors': [2442, 4864, 6097], 'Indeed,': [2456, 4878, 6111], 'increases': [2458, 4880, 6113], 'Chinese': [2492, 4914, 6147], 'hamster': [2493, 4915, 6148], 'ovary': [2494, 4916, 6149], '(35Kapus': [2496, 4918, 6151], 'Szaszi': [2498, 4920, 6153], 'Sun': [2500, 4922, 6155], 'Rizoli': [2502, 4924, 6157], 'Rotstein': [2504, 4926, 6159], 'O.D.': [2505, 4927, 6160], '8093-8102Abstract': [2511, 4933, 6166], '(101)': [2519, 4941, 6174], 'kinase-dependent': [2532, 4954, 6187], 'Scholar).Whereas': [2553, 4975], 'IMCD': [2557, 4979, 6213], 'comparison': [2564, 4986, 6220], 'pattern': [2568, 4990, 6224], 'reveals': [2572, 4994, 6228], 'specificity.': [2575, 4997, 6231], 'agreement': [2577, 4999, 6233], 'JNK': [2606, 2620, 2633, 2641, 5028, 5042, 5055, 5063, 6262, 6276, 6289, 6297], 'contrast': [2614, 5036, 6270], 'marked': [2617, 5039, 6273], '(VC52,': [2627, 5049, 6283], 'VC18).': [2628, 5050, 6284], 'Nevertheless,': [2629, 5051, 6285], 'stimulated': [2632, 5054, 6288], '2-fold': [2636, 5058, 6292], 'considerably': [2644, 5066, 6300], 'lower': [2645, 5067, 6301], '(about': [2651, 2656, 5073, 5078, 6307, 6312], '10-fold)': [2652, 5074, 6308], '4-fold).': [2657, 5079, 6313], 'This': [2658, 2758, 2925, 5080, 5180, 5347, 6314, 6415, 6583], 'higher': [2659, 5081, 6315], 'related': [2667, 5089, 6323], 'pronounced': [2671, 5093, 6327], 'compared': [2679, 5101, 6335], 'NaCl.': [2682, 5104, 6338], 'induce': [2689, 5111, 6345], 'pathway,': [2696, 5118, 6352], 'sensitive': [2700, 5122, 6356], 'pathways.The': [2707, 5129], 'essential': [2711, 2955, 5133, 5377, 6368, 6613], 'mechanism': [2712, 2966, 5134, 5388, 6369, 6624], 'protection': [2715, 2965, 5137, 5387, 6372, 6623], 'against': [2716, 2967, 5138, 5389, 6373, 6625], 'stress.': [2718, 5140, 6375], 'After': [2719, 5141, 6376], 'exhibit': [2726, 5148, 6383], 'involves': [2731, 2860, 5153, 5282, 6388, 6517], '(3Sun': [2737, 2804, 5159, 5226, 6394, 6461], 'sodium': [2761, 5183, 6418], 'influx': [2762, 5184, 6419], 'coupled': [2763, 5185, 6420], 'secondary': [2765, 5187, 6422], 'movements': [2767, 5189, 6424], 'into': [2768, 5190, 6425], 'allows': [2772, 5194, 6429], 'partial': [2774, 5196, 6431], 'recovery': [2775, 5197, 6432], 'confirm': [2794, 5216, 6451], 'undergo': [2798, 5220, 6455], 'show': [2830, 5252, 6487], 'required': [2836, 5258, 6493], 'process,': [2839, 2962, 5261, 5384, 6496, 6620], 'while': [2840, 5262, 6497], 'pathway': [2842, 5264, 6499], 'does': [2843, 5265, 6500], 'appear': [2845, 5267, 6502], 'role.': [2849, 5271, 6506], 'Whether': [2850, 5272, 6507], 'direct': [2857, 2930, 5279, 5352, 6514, 6588], 'intermediate': [2861, 5283, 6518], 'steps': [2862, 5284, 6519], 'determined.': [2866, 5288, 6523], 'Among': [2867, 5289, 6524], 'them,': [2868, 5290, 6525], 'one': [2869, 5291, 6526], 'can': [2870, 5292, 6527], 'postulate': [2871, 5293, 6528], 'p38-dependent': [2876, 5298, 6533], 'cytoskeletal': [2877, 5299, 6534], 'remodeling': [2878, 5300, 6535], 'Scholar).In': [2901, 5323], 'we': [2903, 5325, 6561], 'medium': [2913, 5335, 6571], 'JNK.': [2924, 5346, 6582], 'consequence': [2931, 5353, 6589], 'osmolarity,': [2937, 5359, 6595], 'mediated': [2940, 5362, 6598], 'shrinkage.': [2943, 5365, 6601], 'demonstrates': [2948, 5370, 6606], 'medulla.': [2975, 5397, 6633], 'understood.': [3204], 'Mitogen-activated': [3205], 'Activation': [3921], 'variations.': [4167], 'DISCUSSIONThe': [4168], 'Extracellular': [5445], 'hypertonicity.': [5836], 'Since': [6010], 'Whereas': [6209], 'pathways.': [6363], 'thank': [6635], 'Dr.': [6636], 'Gonin': [6638], 'critical': [6640], 'reading': [6641], 'manuscript.': [6644]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2163418771', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2025-01-06T23:43:17.441926', 'created_date': '2016-06-24'}