Apathy and Depression Following Stroke

Name: Work Video:
Duration: 3 min 30 s
Description: Depression and apathy are the two most frequent behavioral complications of stroke. This article reviews the prevalence of these conditions in poststroke patients, as well as their clinical correlates, longitudinal course, and possible mediators. A number of controlled clinical trials of the efficacy of various drugs in the treatment of poststroke depression are also reviewed.
Sergio Starkstein; Facundo Manes
{'id': 'https://openalex.org/W2151865900', 'doi': 'https://doi.org/10.1017/s1092852900012955', 'title': 'Apathy and Depression Following Stroke', 'display_name': 'Apathy and Depression Following Stroke', 'publication_year': 2000, 'publication_date': '2000-03-01', 'ids': {'openalex': 'https://openalex.org/W2151865900', 'doi': 'https://doi.org/10.1017/s1092852900012955', 'mag': '2151865900', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18277328'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1017/s1092852900012955', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210237982', 'display_name': 'CNS Spectrums', 'issn_l': '1092-8529', 'issn': ['1092-8529', '2165-6509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311721', 'host_organization_name': 'Cambridge University Press', 'host_organization_lineage': ['https://openalex.org/P4310311721', 'https://openalex.org/P4310311702'], 'host_organization_lineage_names': ['Cambridge University Press', 'University of Cambridge'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110244315', 'display_name': 'Sergio Starkstein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100158', 'display_name': 'Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia', 'ror': 'https://ror.org/0145s0423', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210100158']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Sergio E. Starkstein', 'raw_affiliation_strings': ['Department of Neuropsychiatry, Raúl Carrea Institute, Neurological Research-FLENI, Buenos Aires, Argentina.'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuropsychiatry, Raúl Carrea Institute, Neurological Research-FLENI, Buenos Aires, Argentina.', 'institution_ids': ['https://openalex.org/I4210100158']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5026884162', 'display_name': 'Facundo Manes', 'orcid': 'https://orcid.org/0000-0002-1899-1426'}, 'institutions': [{'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Facundo Manes', 'raw_affiliation_strings': ['University of Cambridge'], 'affiliations': [{'raw_affiliation_string': 'University of Cambridge', 'institution_ids': ['https://openalex.org/I241749']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.776, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 26, 'citation_normalized_percentile': {'value': 0.817529, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '5', 'issue': '3', 'first_page': '43', 'last_page': '50'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10510', 'display_name': 'Stroke Rehabilitation and Recovery', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10510', 'display_name': 'Stroke Rehabilitation and Recovery', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10227', 'display_name': 'Acute Ischemic Stroke Management', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11274', 'display_name': 'Botulinum Toxin and Related Neurological Disorders', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/apathy', 'display_name': 'Apathy', 'score': 0.9885814}, {'id': 'https://openalex.org/keywords/depression', 'display_name': 'Depression', 'score': 0.88220936}, {'id': 'https://openalex.org/keywords/stroke', 'display_name': 'Stroke', 'score': 0.7358654}], 'concepts': [{'id': 'https://openalex.org/C2776509080', 'wikidata': 'https://www.wikidata.org/wiki/Q309406', 'display_name': 'Apathy', 'level': 3, 'score': 0.9885814}, {'id': 'https://openalex.org/C2776867660', 'wikidata': 'https://www.wikidata.org/wiki/Q1814941', 'display_name': 'Depression (economics)', 'level': 2, 'score': 0.88220936}, {'id': 'https://openalex.org/C2780645631', 'wikidata': 'https://www.wikidata.org/wiki/Q671554', 'display_name': 'Stroke (engine)', 'level': 2, 'score': 0.7358654}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5768316}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.53725594}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.47795248}, {'id': 'https://openalex.org/C99508421', 'wikidata': 'https://www.wikidata.org/wiki/Q2678675', 'display_name': 'Physical medicine and rehabilitation', 'level': 1, 'score': 0.4230376}, {'id': 'https://openalex.org/C1862650', 'wikidata': 'https://www.wikidata.org/wiki/Q186005', 'display_name': 'Physical therapy', 'level': 1, 'score': 0.37253597}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.34019637}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.17998219}, {'id': 'https://openalex.org/C169900460', 'wikidata': 'https://www.wikidata.org/wiki/Q2200417', 'display_name': 'Cognition', 'level': 2, 'score': 0.07360941}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C162324750', 'wikidata': 'https://www.wikidata.org/wiki/Q8134', 'display_name': 'Economics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C139719470', 'wikidata': 'https://www.wikidata.org/wiki/Q39680', 'display_name': 'Macroeconomics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1017/s1092852900012955', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210237982', 'display_name': 'CNS Spectrums', 'issn_l': '1092-8529', 'issn': ['1092-8529', '2165-6509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311721', 'host_organization_name': 'Cambridge University Press', 'host_organization_lineage': ['https://openalex.org/P4310311721', 'https://openalex.org/P4310311702'], 'host_organization_lineage_names': ['Cambridge University Press', 'University of Cambridge'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18277328', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.82}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1539006433', 'https://openalex.org/W1601342503', 'https://openalex.org/W165579452', 'https://openalex.org/W1776444597', 'https://openalex.org/W1964410923', 'https://openalex.org/W1965466642', 'https://openalex.org/W1981265670', 'https://openalex.org/W1990945773', 'https://openalex.org/W1996249334', 'https://openalex.org/W2007720794', 'https://openalex.org/W2010098758', 'https://openalex.org/W2032398942', 'https://openalex.org/W2035471419', 'https://openalex.org/W2038012828', 'https://openalex.org/W2042527984', 'https://openalex.org/W2044041595', 'https://openalex.org/W2057158486', 'https://openalex.org/W2058391551', 'https://openalex.org/W2069776191', 'https://openalex.org/W2070434316', 'https://openalex.org/W2077965891', 'https://openalex.org/W2085169628', 'https://openalex.org/W2092217950', 'https://openalex.org/W2104474557', 'https://openalex.org/W2112365592', 'https://openalex.org/W2137660780', 'https://openalex.org/W2141523131', 'https://openalex.org/W2141644074', 'https://openalex.org/W2146760890', 'https://openalex.org/W2149544241', 'https://openalex.org/W2151162923', 'https://openalex.org/W2151320551', 'https://openalex.org/W2154569238', 'https://openalex.org/W2157043369', 'https://openalex.org/W2168829761', 'https://openalex.org/W2170053375', 'https://openalex.org/W2200292384', 'https://openalex.org/W2403187759', 'https://openalex.org/W2411644264', 'https://openalex.org/W2412955003', 'https://openalex.org/W2767877434', 'https://openalex.org/W29798592', 'https://openalex.org/W4239680366', 'https://openalex.org/W4317926736', 'https://openalex.org/W74099017'], 'related_works': ['https://openalex.org/W2589856099', 'https://openalex.org/W2480677383', 'https://openalex.org/W2409692858', 'https://openalex.org/W2269265140', 'https://openalex.org/W2182130669', 'https://openalex.org/W2156915339', 'https://openalex.org/W2151865900', 'https://openalex.org/W2130604351', 'https://openalex.org/W2062171362', 'https://openalex.org/W1866982798'], 'abstract_inverted_index': {'Depression': [0], 'and': [1, 31], 'apathy': [2], 'are': [3, 52], 'the': [4, 15, 41, 47], 'two': [5], 'most': [6], 'frequent': [7], 'behavioral': [8], 'complications': [9], 'of': [10, 17, 36, 40, 43, 49], 'stroke.': [11], 'This': [12], 'article': [13], 'reviews': [14], 'prevalence': [16], 'these': [18], 'conditions': [19], 'in': [20, 46], 'poststroke': [21, 50], 'patients,': [22], 'as': [23, 25], 'well': [24], 'their': [26], 'clinical': [27, 38], 'correlates,': [28], 'longitudinal': [29], 'course,': [30], 'possible': [32], 'mediators.': [33], 'A': [34], 'number': [35], 'controlled': [37], 'trials': [39], 'efficacy': [42], 'various': [44], 'drugs': [45], 'treatment': [48], 'depression': [51], 'also': [53], 'reviewed.': [54]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2151865900', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-17T18:18:02.435865', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
