Publication Information

{'id': 'https://openalex.org/W2144009586', 'doi': 'https://doi.org/10.1159/000363323', 'title': 'Heat-Shock Proteins and Acute Ischaemic Kidney Injury', 'display_name': 'Heat-Shock Proteins and Acute Ischaemic Kidney Injury', 'publication_year': 2014, 'publication_date': '2014-06-06', 'ids': {'openalex': 'https://openalex.org/W2144009586', 'doi': 'https://doi.org/10.1159/000363323', 'mag': '2144009586', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24923736'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1159/000363323', 'pdf_url': 'https://karger.com/nee/article-pdf/126/4/167/3793165/000363323.pdf', 'source': {'id': 'https://openalex.org/S143355720', 'display_name': 'Nephron Experimental Nephrology', 'issn_l': '1660-2129', 'issn': ['1660-2129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://karger.com/nee/article-pdf/126/4/167/3793165/000363323.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040963359', 'display_name': 'Stephen O’Neill', 'orcid': 'https://orcid.org/0000-0002-3252-340X'}, 'institutions': [{'id': 'https://openalex.org/I2802789809', 'display_name': 'Edinburgh Royal Infirmary', 'ror': 'https://ror.org/009bsy196', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802789809']}, {'id': 'https://openalex.org/I98677209', 'display_name': 'University of Edinburgh', 'ror': 'https://ror.org/01nrxwf90', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I98677209']}, {'id': 'https://openalex.org/I4210151647', 'display_name': 'Centre for Inflammation Research', 'ror': 'https://ror.org/05wcr1b38', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I4210087105', 'https://openalex.org/I4210151647', 'https://openalex.org/I90344618', 'https://openalex.org/I98677209']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': "Stephen O'Neill", 'raw_affiliation_strings': ['MRC Centre for Inflammation Research, Tissue Injury and Repair Group, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.'], 'affiliations': [{'raw_affiliation_string': 'MRC Centre for Inflammation Research, Tissue Injury and Repair Group, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.', 'institution_ids': ['https://openalex.org/I2802789809', 'https://openalex.org/I98677209', 'https://openalex.org/I4210151647']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075334231', 'display_name': 'Ewen M. Harrison', 'orcid': 'https://orcid.org/0000-0002-5018-3066'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ewen M. Harrison', 'raw_affiliation_strings': ['Deanery of Clinical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Deanery of Clinical Sciences', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112766141', 'display_name': 'James A. Ross', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'James A. Ross', 'raw_affiliation_strings': ['Deanery of Clinical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Deanery of Clinical Sciences', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068413563', 'display_name': 'Stephen J. Wigmore', 'orcid': 'https://orcid.org/0000-0002-3614-8002'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Stephen J. Wigmore', 'raw_affiliation_strings': ['Deanery of Clinical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Deanery of Clinical Sciences', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079055699', 'display_name': 'Jeremy Hughes', 'orcid': 'https://orcid.org/0000-0002-3470-0422'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jeremy Hughes', 'raw_affiliation_strings': ['Deanery of Clinical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Deanery of Clinical Sciences', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.876, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 54, 'citation_normalized_percentile': {'value': 0.593112, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '126', 'issue': '4', 'first_page': '167', 'last_page': '174'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10934', 'display_name': 'Heat shock proteins research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10934', 'display_name': 'Heat shock proteins research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nephrology', 'display_name': 'Nephrology', 'score': 0.5148672}], 'concepts': [{'id': 'https://openalex.org/C205260736', 'wikidata': 'https://www.wikidata.org/wiki/Q418939', 'display_name': 'Heat shock protein', 'level': 3, 'score': 0.71365464}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.57717633}, {'id': 'https://openalex.org/C2780472472', 'wikidata': 'https://www.wikidata.org/wiki/Q424337', 'display_name': 'Acute kidney injury', 'level': 2, 'score': 0.573471}, {'id': 'https://openalex.org/C54847362', 'wikidata': 'https://www.wikidata.org/wiki/Q177635', 'display_name': 'Nephrology', 'level': 2, 'score': 0.5148672}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.50968647}, {'id': 'https://openalex.org/C68991219', 'wikidata': 'https://www.wikidata.org/wiki/Q419102', 'display_name': 'Hsp70', 'level': 4, 'score': 0.5087436}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.49678284}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.44373742}, {'id': 'https://openalex.org/C2781300812', 'wikidata': 'https://www.wikidata.org/wiki/Q178061', 'display_name': 'Shock (circulatory)', 'level': 2, 'score': 0.4151635}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.41388264}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36067396}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.31095058}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.25418395}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.09771204}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006360', 'descriptor_name': 'Heat-Shock Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': True}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D058186', 'descriptor_name': 'Acute Kidney Injury', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006360', 'descriptor_name': 'Heat-Shock Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1159/000363323', 'pdf_url': 'https://karger.com/nee/article-pdf/126/4/167/3793165/000363323.pdf', 'source': {'id': 'https://openalex.org/S143355720', 'display_name': 'Nephron Experimental Nephrology', 'issn_l': '1660-2129', 'issn': ['1660-2129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24923736', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1159/000363323', 'pdf_url': 'https://karger.com/nee/article-pdf/126/4/167/3793165/000363323.pdf', 'source': {'id': 'https://openalex.org/S143355720', 'display_name': 'Nephron Experimental Nephrology', 'issn_l': '1660-2129', 'issn': ['1660-2129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.83, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1608860417', 'https://openalex.org/W1964969285', 'https://openalex.org/W1971799714', 'https://openalex.org/W1972121275', 'https://openalex.org/W1972994868', 'https://openalex.org/W1975200549', 'https://openalex.org/W1978917041', 'https://openalex.org/W1985209496', 'https://openalex.org/W1989916602', 'https://openalex.org/W1992326746', 'https://openalex.org/W1998631287', 'https://openalex.org/W2003810250', 'https://openalex.org/W2015245182', 'https://openalex.org/W2019442978', 'https://openalex.org/W2028570171', 'https://openalex.org/W2039535160', 'https://openalex.org/W2041174049', 'https://openalex.org/W2051083202', 'https://openalex.org/W2066127279', 'https://openalex.org/W2067176564', 'https://openalex.org/W2073625832', 'https://openalex.org/W2077781001', 'https://openalex.org/W2084162564', 'https://openalex.org/W2089400513', 'https://openalex.org/W2097806697', 'https://openalex.org/W2108298583', 'https://openalex.org/W2114435275', 'https://openalex.org/W2118299296', 'https://openalex.org/W2144809135', 'https://openalex.org/W2189364323', 'https://openalex.org/W2371948111'], 'related_works': ['https://openalex.org/W3150918846', 'https://openalex.org/W2411775713', 'https://openalex.org/W2379220137', 'https://openalex.org/W2353187387', 'https://openalex.org/W2081402053', 'https://openalex.org/W2075809176', 'https://openalex.org/W2061936937', 'https://openalex.org/W2021879337', 'https://openalex.org/W2014434155', 'https://openalex.org/W2001704527'], 'abstract_inverted_index': {'The': [0], 'incidence': [1], 'of': [2, 28, 65, 72, 86, 98, 102, 120, 133, 152, 156, 164, 180, 194, 201], 'acute': [3], 'kidney': [4, 29, 59], 'injury': [5, 9], 'due': [6], 'to': [7, 34, 137, 146, 177, 197], 'ischaemia-reperfusion': [8], '(IRI)': [10], 'is': [11, 23, 63, 158, 171], 'rising': [12], 'but': [13, 144], 'effective': [14], 'treatments': [15], 'and': [16, 31, 44, 52, 76, 95, 118, 140, 190], 'preventative': [17], 'approaches': [18], 'are': [19, 41, 91], 'currently': [20], 'lacking.': [21], 'IRI': [22, 90, 189], 'also': [24], 'an': [25, 148], 'inevitable': [26], 'consequence': [27], 'transplantation': [30], 'significantly': [32], 'contributes': [33], 'delayed': [35], 'graft': [36], 'function.': [37], 'Heat-shock': [38], 'proteins': [39], '(Hsps)': [40], 'highly': [42], 'conserved': [43], 'ubiquitously': [45], 'expressed': [46], 'molecular': [47], 'chaperones': [48], 'that': [49], 'help': [50], 'maintain': [51], 'restore': [53], 'normal': [54], 'cellular': [55], 'function': [56], 'in': [57, 88, 110], 'the': [58, 66, 83, 131, 153, 178, 192], 'following': [60, 187], 'IRI.': [61], 'Hsp70': [62, 87, 139, 157], 'one': [64], 'most': [67], 'frequently': [68], 'studied': [69], 'Hsps': [70], 'because': [71], 'potential': [73], 'cytoprotective': [74], 'properties': [75, 85], 'attractiveness': [77], 'as': [78, 173], 'a': [79, 198], 'therapeutic': [80, 182], 'target.': [81], 'However,': [82], 'protective': [84, 154], 'renal': [89, 142, 188], 'not': [92], 'fully': [93], 'understood': [94], 'putative': [96], 'modes': [97], 'protection': [99], 'include': [100], 'correction': [101], 'protein': [103], 'conformation,': [104], 'cytoskeletal': [105], 'stabilisation,': [106], 'anti-inflammatory': [107], 'effects,': [108], 'requirement': [109], 'autophagy,': [111], 'anti-apoptotic': [112], 'properties,': [113], 'influence': [114], 'over': [115], 'macrophage': [116], 'phenotype': [117], 'stimulation': [119], 'regulatory': [121], 'T': [122], 'cells.': [123], 'Significant': [124], 'clinical': [125], 'interest': [126], 'has': [127], 'been': [128], 'generated': [129], 'about': [130], 'possibility': [132], 'applying': [134], 'pharmacological': [135], 'agents': [136], 'induce': [138], 'prevent': [141], 'IRI,': [143], 'prior': [145], 'this,': [147], 'increased': [149], 'mechanistic': [150], 'understanding': [151], 'nature': [155], 'needed.': [159], 'In': [160], 'particular,': [161], 'further': [162], 'investigation': [163], 'Hsp': [165], 'expression': [166], 'on': [167], 'inflammatory': [168], 'cell': [169], 'behaviour': [170], 'required': [172], 'this': [174], 'could': [175], 'lead': [176], 'development': [179], 'new': [181], 'strategies': [183], 'for': [184], 'enhancing': [185], 'recovery': [186], 'broaden': [191], 'range': [193], 'these': [195], 'therapies': [196], 'wider': [199], 'group': [200], 'patients.': [202]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2144009586', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 8}], 'updated_date': '2024-12-14T21:41:10.424792', 'created_date': '2016-06-24'}