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'cells': [19, 58, 84, 108, 123, 146, 198], 'most': [21], 'closely': [22], 'linked': [23], 'the': [25, 28, 32, 95, 100, 161, 232, 246], 'locus': [26, 43], 'containing': [27], 'gene.': [30], 'However,': [31], 'molecular': [33], 'mechanism': [34], 'underlying': [35], 'genetic': [36], 'control': [37], 'of': [38, 76, 102, 136, 170, 175, 234, 250], 'sensitivity': [40, 227], 'this': [42, 50], 'has': [44], 'not': [45, 86], 'been': [46], 'fully': [47], 'elucidated.': [48], 'In': [49, 80, 192, 221], 'study,': [51], 'we': [52, 223], 'revealed': [53, 224], 'that': [54, 112, 127, 225], 'C57BL/6': [55], '(B6)': [56], 'respond': [59], 'mAb-induced,': [61], 'TLR4-specific': [62], 'signals': [63], 'stronger': [64], 'than': [65, 126, 188], 'BALB/c': [66], '(BALB)': [67], 'cells,': [69, 116], 'as': [70, 160, 215], 'assessed': [71, 216], 'proliferation': [73], 'upregulation': [75], 'CD69': [77], 'CD86.': [79], 'contrast,': [81], 'BALB': [82, 106, 121, 137, 151, 171, 180, 201, 251], 'were': [85, 147, 207], 'hyporesponsive': [87, 208, 248], 'agonistic': [89], 'anti–radioprotective': [90], 'mAb': [93], 'or': [94], 'TLR9': [96], 'agonist': [97], 'CpG.': [98], 'Although': [99], 'level': [101, 233], 'mRNA': [104], 'was': [109, 124, 139, 185], 'comparable': [110], 'with': [111, 149, 194, 200, 210, 212], 'B6': [114, 129, 189, 213], 'surface': [117, 134, 168, 235], 'expression': [119, 135, 153, 169, 237], 'lower': [125, 133, 167, 187], 'This': [132], 'also': [140], 'observed': [141], 'when': [142], 'HEK293': [143], 'Ba/F3': [145, 197], 'transfected': [148, 199], 'a': [150, 157], 'construct.': [154], 'We': [155], 'identified': [156], 'V254I': [158, 242], 'mutation': [159, 243], 'responsible': [162], 'single': [163], 'nucleotide': [164], 'polymorphism': [165], 'for': [166, 245], 'TLR4.': [172], 'Furthermore,': [173], 'cotransfection': [174], 'myeloid': [176, 204], 'differentiation': [177, 205], 'factor-2': [178, 206], 'increased': [179], 'expression,': [182, 196], 'although': [183], 'it': [184], 'still': [186], 'expression.': [191], 'concordance': [193], 'reduced': [195], 'compared': [209], 'those': [211], 'TLR4,': [214], 'LPS-induced': [218], 'NF-κB': [219], 'activation.': [220], 'conclusion,': [222], 'genetically': [229], 'controlled': [230], 'on': [238], 'A': [241], 'accounts': [244], 'phenotype': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2138278198', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-09-17T16:34:02.309193', 'created_date': '2016-06-24'}