Title: Synthesis of Pyridines by Carbenoid‐Mediated Ring Opening of 2<i>H</i>‐Azirines
Abstract: Angewandte Chemie International EditionVolume 52, Issue 8 p. 2212-2216 Communication Synthesis of Pyridines by Carbenoid-Mediated Ring Opening of 2H-Azirines† Nicole S. Y. Loy, Nicole S. Y. Loy Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorDr. Alok Singh, Dr. Alok Singh Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorDr. Xianxiu Xu, Dr. Xianxiu Xu Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorProf. Cheol-Min Park, Corresponding Author Prof. Cheol-Min Park [email protected] Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)===Search for more papers by this author Nicole S. Y. Loy, Nicole S. Y. Loy Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorDr. Alok Singh, Dr. Alok Singh Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorDr. Xianxiu Xu, Dr. Xianxiu Xu Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Search for more papers by this authorProf. Cheol-Min Park, Corresponding Author Prof. Cheol-Min Park [email protected] Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)===Search for more papers by this author First published: 10 January 2013 https://doi.org/10.1002/anie.201209301Citations: 128 † We thank Dr. Rakesh Ganguly for X-ray crystallographic analysis. We acknowledge the Nanyang Technological University for financial support. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Roaming the range: The title reaction tolerates a wide range of substituents on the resulting pyridine ring using mild reaction conditions (see scheme; esp=α,α,α′,α′-tetramethyl-1,3-benzenedipropionic acid). The formation of the key intermediate is catalyst-controlled, and subsequent cyclization and oxidation affords pyridines in excellent yields. The method has been used for the efficient synthesis of polyarylpyridines. Citing Literature Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description anie_201209301_sm_miscellaneous_information.pdf7 MB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume52, Issue8February 18, 2013Pages 2212-2216 RelatedInformation
Publication Year: 2013
Publication Date: 2013-01-10
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 141
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