Publication Information

{'id': 'https://openalex.org/W2126547373', 'doi': 'https://doi.org/10.1128/jvi.66.12.7319-7327.1992', 'title': 'A constitutive enhancer in the bovine papillomavirus upstream regulatory region shares genetic elements with the viral P1 promoter', 'display_name': 'A constitutive enhancer in the bovine papillomavirus upstream regulatory region shares genetic elements with the viral P1 promoter', 'publication_year': 1992, 'publication_date': '1992-12-01', 'ids': {'openalex': 'https://openalex.org/W2126547373', 'doi': 'https://doi.org/10.1128/jvi.66.12.7319-7327.1992', 'mag': '2126547373', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1331522', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/240436'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.66.12.7319-7327.1992', 'pdf_url': 'https://jvi.asm.org/content/jvi/66/12/7319.full.pdf', 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jvi.asm.org/content/jvi/66/12/7319.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5024239177', 'display_name': 'G L Bream', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'G L Bream', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley 94720.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley 94720.', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109115391', 'display_name': 'Peter Vaillancourt', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'P Vaillancourt', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley 94720.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley 94720.', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072265713', 'display_name': 'Michael R. Botchan', 'orcid': 'https://orcid.org/0000-0003-0459-5518'}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M R Botchan', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley 94720.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley 94720.', 'institution_ids': ['https://openalex.org/I95457486']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.138, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.277126, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 61, 'max': 65}, 'biblio': {'volume': '66', 'issue': '12', 'first_page': '7319', 'last_page': '7327'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11970', 'display_name': 'Molecular Biology Techniques and Applications', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11970', 'display_name': 'Molecular Biology Techniques and Applications', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11560', 'display_name': 'Animal Disease Management and Epidemiology', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1102', 'display_name': 'Agronomy and Crop Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11688', 'display_name': 'Microbial infections and disease research', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tata-box', 'display_name': 'TATA box', 'score': 0.8574265}, {'id': 'https://openalex.org/keywords/upstream-activating-sequence', 'display_name': 'Upstream activating sequence', 'score': 0.81721705}, {'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription', 'score': 0.6409333}], 'concepts': [{'id': 'https://openalex.org/C65888428', 'wikidata': 'https://www.wikidata.org/wiki/Q1413955', 'display_name': 'TATA box', 'level': 5, 'score': 0.8574265}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8559874}, {'id': 'https://openalex.org/C111936080', 'wikidata': 'https://www.wikidata.org/wiki/Q913367', 'display_name': 'Enhancer', 'level': 4, 'score': 0.85349536}, {'id': 'https://openalex.org/C192245184', 'wikidata': 'https://www.wikidata.org/wiki/Q3552104', 'display_name': 'Upstream activating sequence', 'level': 5, 'score': 0.81721705}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.7493189}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.6409333}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.5362816}, {'id': 'https://openalex.org/C21592294', 'wikidata': 'https://www.wikidata.org/wiki/Q3238407', 'display_name': 'Regulatory sequence', 'level': 4, 'score': 0.46978632}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.3791678}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.37150687}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.36926848}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.1785303}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D052688', 'descriptor_name': 'Bovine papillomavirus 1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004742', 'descriptor_name': 'Enhancer Elements, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012045', 'descriptor_name': 'Regulatory Sequences, Nucleic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052688', 'descriptor_name': 'Bovine papillomavirus 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004279', 'descriptor_name': 'DNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004279', 'descriptor_name': 'DNA, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015183', 'descriptor_name': 'Restriction Mapping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017384', 'descriptor_name': 'Sequence Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016385', 'descriptor_name': 'TATA Box', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.66.12.7319-7327.1992', 'pdf_url': 'https://jvi.asm.org/content/jvi/66/12/7319.full.pdf', 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc240436', 'pdf_url': 'https://europepmc.org/articles/pmc240436?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC240436', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1331522', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.66.12.7319-7327.1992', 'pdf_url': 'https://jvi.asm.org/content/jvi/66/12/7319.full.pdf', 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1507430705', 'https://openalex.org/W1530466930', 'https://openalex.org/W1531193576', 'https://openalex.org/W1558516755', 'https://openalex.org/W1564353516', 'https://openalex.org/W1570914391', 'https://openalex.org/W1773673462', 'https://openalex.org/W1807776979', 'https://openalex.org/W1824048966', 'https://openalex.org/W1826374502', 'https://openalex.org/W1841154473', 'https://openalex.org/W1857592834', 'https://openalex.org/W1875676655', 'https://openalex.org/W1904489013', 'https://openalex.org/W1936008327', 'https://openalex.org/W1942615074', 'https://openalex.org/W1964129540', 'https://openalex.org/W1981929643', 'https://openalex.org/W1992476328', 'https://openalex.org/W1998162329', 'https://openalex.org/W2011655388', 'https://openalex.org/W2020830418', 'https://openalex.org/W2045135216', 'https://openalex.org/W2046328458', 'https://openalex.org/W2052357638', 'https://openalex.org/W2094571268', 'https://openalex.org/W2101290459', 'https://openalex.org/W2169923167', 'https://openalex.org/W2170499910', 'https://openalex.org/W290843212', 'https://openalex.org/W4210962320', 'https://openalex.org/W4232332165', 'https://openalex.org/W57919567'], 'related_works': ['https://openalex.org/W4296940635', 'https://openalex.org/W4283214369', 'https://openalex.org/W4281254649', 'https://openalex.org/W4249725176', 'https://openalex.org/W3208446472', 'https://openalex.org/W3156071777', 'https://openalex.org/W2128539416', 'https://openalex.org/W2086896720', 'https://openalex.org/W1971558040', 'https://openalex.org/W1942920824'], 'abstract_inverted_index': {'The': [0, 138], 'bovine': [1], 'papillomavirus': [2], 'upstream': [3, 43, 65, 108], 'regulatory': [4, 44], 'region': [5], 'represents': [6], 'a': [7, 52, 110, 134], 'common': [8], 'element': [9], 'in': [10, 133, 160, 194], 'the': [11, 16, 24, 30, 38, 42, 81, 117, 145, 174, 181, 185, 190], 'regulation': [12], 'of': [13, 41, 63, 80, 109, 140, 147], 'transcription': [14, 28, 48], 'from': [15, 29, 49, 120, 126], 'five': [17], 'early': [18], 'viral': [19, 31], 'promoters.': [20, 169], 'We': [21], 'have': [22, 163], 'determined': [23], 'sequences': [25, 77, 91, 176], 'required': [26, 178], 'for': [27, 97], 'P1': [32, 50, 148, 182], 'promoter,': [33], 'which': [34, 74], 'is': [35], 'located': [36], 'at': [37], "5'": [39], 'end': [40], 'region.': [45], 'In': [46, 84], 'vitro': [47], 'requires': [51, 88], '123-bp': [53], 'fragment': [54], '(nucleotides': [55], '7153': [56], 'to': [57, 60, 76, 122, 154, 166], '7275;': [58], '-33': [59], '+90)': [61], 'consisting': [62], 'an': [64, 71], 'TATA-like': [66], 'sequence': [67, 107, 119], 'as': [68, 70], 'well': [69], 'unidentified': [72], 'protein': [73], 'binds': [75], 'immediately': [78], 'downstream': [79, 90, 118, 168], 'initiation': [82], 'site.': [83], 'vivo,': [85], 'this': [86, 155, 161], 'promoter': [87, 183], 'additional': [89, 105], '(to': [92], 'position': [93], '+160;': [94], 'nucleotide': [95], '7345)': [96], 'maximal': [98], 'activity': [99], 'but': [100], 'does': [101], 'not': [102], 'require': [103], 'any': [104], 'DNA': [106], 'putative': [111], 'TATA': [112], 'box.': [113], 'Four': [114], 'regions': [115], 'within': [116], '+9': [121], '+160': [123], 'are': [124, 177], 'protected': [125], 'DNase': [127], 'I': [128], 'digestion': [129], 'by': [130, 179], 'proteins': [131, 192], 'present': [132], 'HeLa': [135], 'cell': [136], 'extract.': [137], 'presence': [139], 'these': [141], 'sites': [142], 'correlates': [143], 'with': [144], 'level': [146], 'activity.': [149], 'A': [150], 'constitutive': [151, 186], 'enhancer': [152, 162], 'maps': [153], 'same': [156, 175, 191], 'region,': [157], 'and': [158, 184], 'mutations': [159], 'been': [164], 'shown': [165], 'affect': [167], 'Deletion': [170], 'analysis': [171], 'indicates': [172], 'that': [173, 189], 'both': [180, 195], 'enhancer,': [187], 'suggesting': [188], 'function': [193], 'activities.': [196]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2126547373', 'counts_by_year': [], 'updated_date': '2024-12-10T05:47:17.928008', 'created_date': '2016-06-24'}