Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2124205618', 'doi': 'https://doi.org/10.1261/rna.958908', 'title': 'A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L', 'display_name': 'A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L', 'publication_year': 2008, 'publication_date': '2008-04-21', 'ids': {'openalex': 'https://openalex.org/W2124205618', 'doi': 'https://doi.org/10.1261/rna.958908', 'mag': '2124205618', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18426919', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2390801'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1261/rna.958908', 'pdf_url': 'http://rnajournal.cshlp.org/content/14/6/1026.full.pdf', 'source': {'id': 'https://openalex.org/S187657468', 'display_name': 'RNA', 'issn_l': '1355-8382', 'issn': ['1355-8382', '1469-9001'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://rnajournal.cshlp.org/content/14/6/1026.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034207177', 'display_name': 'Hannah L. Townsend', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I921990950', 'display_name': 'University of Colorado Denver', 'ror': 'https://ror.org/02hh7en24', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I921990950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hannah L. Townsend', 'raw_affiliation_strings': ['Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA', 'institution_ids': ['https://openalex.org/I921990950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057121925', 'display_name': 'Babal K. Jha', 'orcid': 'https://orcid.org/0000-0002-7660-5255'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Babal K. Jha', 'raw_affiliation_strings': ['Department of Cancer Biology, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44106, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Biology, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44106, USA', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052844005', 'display_name': 'Jian Han', 'orcid': 'https://orcid.org/0000-0002-6257-8882'}, 'institutions': [{'id': 'https://openalex.org/I921990950', 'display_name': 'University of Colorado Denver', 'ror': 'https://ror.org/02hh7en24', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I921990950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jian-Qiu Han', 'raw_affiliation_strings': ['Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA', 'institution_ids': ['https://openalex.org/I921990950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032433182', 'display_name': 'Nasib K. Maluf', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I921990950', 'display_name': 'University of Colorado Denver', 'ror': 'https://ror.org/02hh7en24', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I921990950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'N. Karl Maluf', 'raw_affiliation_strings': ['Department of Pharmaceutical Sciences, University of Colorado Denver, School of Pharmacy, Aurora, Colorado 80045, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutical Sciences, University of Colorado Denver, School of Pharmacy, Aurora, Colorado 80045, USA', 'institution_ids': ['https://openalex.org/I921990950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067358586', 'display_name': 'Robert H. Silverman', 'orcid': 'https://orcid.org/0000-0003-2432-992X'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert H. Silverman', 'raw_affiliation_strings': ['Department of Cancer Biology, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44106, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Biology, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44106, USA', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052829441', 'display_name': 'David J. Barton', 'orcid': 'https://orcid.org/0000-0002-1991-6268'}, 'institutions': [{'id': 'https://openalex.org/I921990950', 'display_name': 'University of Colorado Denver', 'ror': 'https://ror.org/02hh7en24', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I921990950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David J. Barton', 'raw_affiliation_strings': ['Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA', 'Program in Molecular Biology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA', 'institution_ids': ['https://openalex.org/I921990950']}, {'raw_affiliation_string': 'Program in Molecular Biology, University of Colorado Denver, School of Medicine, Aurora, Colorado 80045, USA', 'institution_ids': ['https://openalex.org/I921990950']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.747, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 54, 'citation_normalized_percentile': {'value': 0.911151, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '14', 'issue': '6', 'first_page': '1026', 'last_page': '1036'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11112', 'display_name': 'Aetiology, Diagnosis, and Management of Myocarditis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11112', 'display_name': 'Aetiology, Diagnosis, and Management of Myocarditis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10976', 'display_name': 'Gastrointestinal Viral Infections and Vaccines Development', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/endoribonuclease', 'display_name': 'Endoribonuclease', 'score': 0.97727907}, {'id': 'https://openalex.org/keywords/rnase-mrp', 'display_name': 'RNase MRP', 'score': 0.7073004}, {'id': 'https://openalex.org/keywords/rnase-h', 'display_name': 'RNase H', 'score': 0.5730686}, {'id': 'https://openalex.org/keywords/rnase-ph', 'display_name': 'RNase PH', 'score': 0.5466256}, {'id': 'https://openalex.org/keywords/rna-structure', 'display_name': 'RNA Structure', 'score': 0.521179}, {'id': 'https://openalex.org/keywords/trna', 'display_name': 'tRNA', 'score': 0.516685}, {'id': 'https://openalex.org/keywords/degradosome', 'display_name': 'Degradosome', 'score': 0.50864995}, {'id': 'https://openalex.org/keywords/rna-silencing', 'display_name': 'RNA silencing', 'score': 0.4966269}, {'id': 'https://openalex.org/keywords/ribonuclease-iii', 'display_name': 'Ribonuclease III', 'score': 0.45490417}], 'concepts': [{'id': 'https://openalex.org/C2780102198', 'wikidata': 'https://www.wikidata.org/wiki/Q3054027', 'display_name': 'Endoribonuclease', 'level': 5, 'score': 0.97727907}, {'id': 'https://openalex.org/C10879258', 'wikidata': 'https://www.wikidata.org/wiki/Q76826611', 'display_name': 'RNase P', 'level': 4, 'score': 0.79631734}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.74933267}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.74426043}, {'id': 'https://openalex.org/C195500695', 'wikidata': 'https://www.wikidata.org/wiki/Q7277299', 'display_name': 'RNase MRP', 'level': 5, 'score': 0.7073004}, {'id': 'https://openalex.org/C69766542', 'wikidata': 'https://www.wikidata.org/wiki/Q3430179', 'display_name': 'RNase H', 'level': 5, 'score': 0.5730686}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.561802}, {'id': 'https://openalex.org/C188528350', 'wikidata': 'https://www.wikidata.org/wiki/Q3415271', 'display_name': 'RNase PH', 'level': 5, 'score': 0.5466256}, {'id': 'https://openalex.org/C42369531', 'wikidata': 'https://www.wikidata.org/wiki/Q22328565', 'display_name': 'Degradosome', 'level': 5, 'score': 0.50864995}, {'id': 'https://openalex.org/C2191507', 'wikidata': 'https://www.wikidata.org/wiki/Q7277185', 'display_name': 'RNA silencing', 'level': 5, 'score': 0.4966269}, {'id': 'https://openalex.org/C79750893', 'wikidata': 'https://www.wikidata.org/wiki/Q3430180', 'display_name': 'Ribonuclease III', 'level': 5, 'score': 0.45490417}, {'id': 'https://openalex.org/C2778976237', 'wikidata': 'https://www.wikidata.org/wiki/Q422523', 'display_name': 'Ribonuclease', 'level': 4, 'score': 0.45267227}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.38251147}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.114919215}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0670518}], 'mesh': [{'descriptor_ui': 'D004722', 'descriptor_name': 'Endoribonucleases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D030015', 'descriptor_name': 'Enterovirus C, Human', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000227', 'descriptor_name': 'Adenine Nucleotides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000227', 'descriptor_name': 'Adenine Nucleotides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000227', 'descriptor_name': 'Adenine Nucleotides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000227', 'descriptor_name': 'Adenine Nucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004722', 'descriptor_name': 'Endoribonucleases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004722', 'descriptor_name': 'Endoribonucleases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D030015', 'descriptor_name': 'Enterovirus C, Human', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D030015', 'descriptor_name': 'Enterovirus C, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D030015', 'descriptor_name': 'Enterovirus C, Human', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D031541', 'descriptor_name': 'Fluorescence Resonance Energy Transfer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009690', 'descriptor_name': 'Nucleic Acid Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017955', 'descriptor_name': 'Poliovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017955', 'descriptor_name': 'Poliovirus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1261/rna.958908', 'pdf_url': 'http://rnajournal.cshlp.org/content/14/6/1026.full.pdf', 'source': {'id': 'https://openalex.org/S187657468', 'display_name': 'RNA', 'issn_l': '1355-8382', 'issn': ['1355-8382', '1469-9001'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2390801', 'pdf_url': 'https://europepmc.org/articles/pmc2390801?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390801', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18426919', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1261/rna.958908', 'pdf_url': 'http://rnajournal.cshlp.org/content/14/6/1026.full.pdf', 'source': {'id': 'https://openalex.org/S187657468', 'display_name': 'RNA', 'issn_l': '1355-8382', 'issn': ['1355-8382', '1469-9001'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W145168120', 'https://openalex.org/W1525055187', 'https://openalex.org/W1786024553', 'https://openalex.org/W1964831029', 'https://openalex.org/W1970677867', 'https://openalex.org/W1974054239', 'https://openalex.org/W1993554600', 'https://openalex.org/W1997614771', 'https://openalex.org/W1998686668', 'https://openalex.org/W2002085466', 'https://openalex.org/W2009818318', 'https://openalex.org/W2014250634', 'https://openalex.org/W2017162371', 'https://openalex.org/W2018015019', 'https://openalex.org/W2018071918', 'https://openalex.org/W2020693276', 'https://openalex.org/W2022057836', 'https://openalex.org/W2032656149', 'https://openalex.org/W2039361749', 'https://openalex.org/W2042266259', 'https://openalex.org/W2042416385', 'https://openalex.org/W2046013214', 'https://openalex.org/W2050963689', 'https://openalex.org/W2056936680', 'https://openalex.org/W2057198760', 'https://openalex.org/W2070186833', 'https://openalex.org/W2076664218', 'https://openalex.org/W2087004183', 'https://openalex.org/W2087333401', 'https://openalex.org/W2094191346', 'https://openalex.org/W2101039718', 'https://openalex.org/W2101083359', 'https://openalex.org/W2102701872', 'https://openalex.org/W2113287929', 'https://openalex.org/W2114067488', 'https://openalex.org/W2139405922', 'https://openalex.org/W2141157874', 'https://openalex.org/W2141660858', 'https://openalex.org/W2153487904', 'https://openalex.org/W2157271780', 'https://openalex.org/W2166343003', 'https://openalex.org/W2167095297', 'https://openalex.org/W2409191177', 'https://openalex.org/W2418899938', 'https://openalex.org/W2758140061', 'https://openalex.org/W59240946', 'https://openalex.org/W974691727'], 'related_works': ['https://openalex.org/W71982098', 'https://openalex.org/W2418173525', 'https://openalex.org/W2168912093', 'https://openalex.org/W2146318460', 'https://openalex.org/W2115572303', 'https://openalex.org/W2072113030', 'https://openalex.org/W2062289468', 'https://openalex.org/W2055505335', 'https://openalex.org/W2026503668', 'https://openalex.org/W1002073993'], 'abstract_inverted_index': {'Ribonuclease': [0], 'L': [1, 127, 179, 184], '(RNase': [2, 183], 'L)': [3], 'is': [4], 'a': [5, 38, 113, 139, 146, 157], 'latent': [6], 'endoribonuclease': [7, 62, 99, 144, 167], 'in': [8, 45, 119], 'an': [9, 109], 'evolutionarily': [10], 'ancient': [11], 'interferon-regulated': [12], 'dsRNA-activated': [13, 22], 'antiviral': [14], 'pathway.': [15], "2'-5'": [16], 'oligoadenylate': [17, 23], '(2-5A),': [18], 'the': [19, 31, 46, 49, 61, 72, 94, 98, 130, 143, 153, 160, 164, 177], 'product': [20], 'of': [21, 34, 40, 48, 64, 125, 142, 148, 156, 169], 'synthetases': [24], '(OASes),': [25], 'binds': [26], 'to': [27, 90, 122], 'ankyrin': [28], 'repeats': [29], 'near': [30], 'amino': [32], 'terminus': [33], 'RNase': [35, 65, 81, 91, 104, 126, 170, 178], 'L,': [36, 105], 'initiating': [37], 'series': [39], 'conformational': [41], 'changes': [42], 'that': [43], 'result': [44], 'activation': [47], 'endoribonuclease.': [50], 'A': [51], 'phylogenetically': [52], 'conserved': [53], 'RNA': [54, 79, 84, 96, 110, 137, 162, 176, 182], 'structure': [55], 'within': [56], 'group': [57, 76, 134], 'C': [58, 77, 135], 'enteroviruses': [59], 'inhibits': [60, 80], 'activity': [63, 128], 'L.': [66, 82, 92, 171], 'In': [67], 'this': [68, 174], 'study': [69], 'we': [70], 'report': [71], 'mechanism': [73], 'by': [74, 129], 'which': [75], 'enterovirus': [78, 136], 'Viral': [83], 'did': [85], 'not': [86], 'affect': [87], '2-5A': [88], 'binding': [89], 'Rather,': [93], 'viral': [95, 131, 161, 175], 'inhibited': [97, 163], 'domain.': [100], 'We': [101, 172], 'used': [102], 'purified': [103, 106], '2-5A,': [107], 'and': [108, 116], 'substrate': [111], 'with': [112, 145, 152], "5'": [114], 'fluorophore': [115], "3'": [117], 'quencher': [118], 'FRET': [120], 'assays': [121], 'measure': [123], 'inhibition': [124], 'RNA.': [132], 'The': [133], 'was': [138], 'competitive': [140, 158, 180], 'inhibitor': [141, 181], 'K(i)': [147], '34': [149], 'nM.': [150], 'Consistent': [151], 'kinetic': [154], 'profile': [155], 'inhibitor,': [159], 'constitutively': [165], 'active': [166], 'domain': [168], 'call': [173], 'ciRNA).': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2124205618', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-09-11T15:26:10.538517', 'created_date': '2016-06-24'}