Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2026503668', 'doi': 'https://doi.org/10.1073/pnas.80.14.4450', 'title': 'Identification of a precursor molecular for the RNA moiety of the processing enzyme RNase P.', 'display_name': 'Identification of a precursor molecular for the RNA moiety of the processing enzyme RNase P.', 'publication_year': 1983, 'publication_date': '1983-07-01', 'ids': {'openalex': 'https://openalex.org/W2026503668', 'doi': 'https://doi.org/10.1073/pnas.80.14.4450', 'mag': '2026503668', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/6192433', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/384056'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.80.14.4450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc384056?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5053799789', 'display_name': 'Michael Gurevitz', 'orcid': 'https://orcid.org/0000-0001-6436-6878'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M Gurevitz', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011268440', 'display_name': 'Swatantra Kumar Jain', 'orcid': 'https://orcid.org/0000-0002-3899-0121'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S K Jain', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060497759', 'display_name': 'David Apirion', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D Apirion', 'raw_affiliation_strings': ['Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Washington University Medical School, Box 8093, St. Louis, Missouri 63110', 'institution_ids': ['https://openalex.org/I204465549']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.179, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 46, 'citation_normalized_percentile': {'value': 0.887344, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '80', 'issue': '14', 'first_page': '4450', 'last_page': '4454'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/endoribonuclease', 'display_name': 'Endoribonuclease', 'score': 0.85693574}, {'id': 'https://openalex.org/keywords/degradosome', 'display_name': 'Degradosome', 'score': 0.79355645}, {'id': 'https://openalex.org/keywords/exosome-complex', 'display_name': 'Exosome complex', 'score': 0.77799416}, {'id': 'https://openalex.org/keywords/rnase-mrp', 'display_name': 'RNase MRP', 'score': 0.63564837}, {'id': 'https://openalex.org/keywords/rnase-h', 'display_name': 'RNase H', 'score': 0.5916887}, {'id': 'https://openalex.org/keywords/rnase-ph', 'display_name': 'RNase PH', 'score': 0.54990596}, {'id': 'https://openalex.org/keywords/ribonuclease-iii', 'display_name': 'Ribonuclease III', 'score': 0.522985}, {'id': 'https://openalex.org/keywords/post-transcriptional-modification', 'display_name': 'Post-transcriptional modification', 'score': 0.48376727}, {'id': 'https://openalex.org/keywords/nuclease-protection-assay', 'display_name': 'Nuclease protection assay', 'score': 0.454331}], 'concepts': [{'id': 'https://openalex.org/C2780102198', 'wikidata': 'https://www.wikidata.org/wiki/Q3054027', 'display_name': 'Endoribonuclease', 'level': 5, 'score': 0.85693574}, {'id': 'https://openalex.org/C10879258', 'wikidata': 'https://www.wikidata.org/wiki/Q76826611', 'display_name': 'RNase P', 'level': 4, 'score': 0.84065366}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.83516437}, {'id': 'https://openalex.org/C42369531', 'wikidata': 'https://www.wikidata.org/wiki/Q22328565', 'display_name': 'Degradosome', 'level': 5, 'score': 0.79355645}, {'id': 'https://openalex.org/C75449159', 'wikidata': 'https://www.wikidata.org/wiki/Q418869', 'display_name': 'Exosome complex', 'level': 5, 'score': 0.77799416}, {'id': 'https://openalex.org/C195500695', 'wikidata': 'https://www.wikidata.org/wiki/Q7277299', 'display_name': 'RNase MRP', 'level': 5, 'score': 0.63564837}, {'id': 'https://openalex.org/C194993378', 'wikidata': 'https://www.wikidata.org/wiki/Q427087', 'display_name': 'Non-coding RNA', 'level': 4, 'score': 0.5978422}, {'id': 'https://openalex.org/C69766542', 'wikidata': 'https://www.wikidata.org/wiki/Q3430179', 'display_name': 'RNase H', 'level': 5, 'score': 0.5916887}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.55859697}, {'id': 'https://openalex.org/C188528350', 'wikidata': 'https://www.wikidata.org/wiki/Q3415271', 'display_name': 'RNase PH', 'level': 5, 'score': 0.54990596}, {'id': 'https://openalex.org/C79750893', 'wikidata': 'https://www.wikidata.org/wiki/Q3430180', 'display_name': 'Ribonuclease III', 'level': 5, 'score': 0.522985}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.51614916}, {'id': 'https://openalex.org/C21786251', 'wikidata': 'https://www.wikidata.org/wiki/Q14886350', 'display_name': 'RNA editing', 'level': 4, 'score': 0.49238145}, {'id': 'https://openalex.org/C22232683', 'wikidata': 'https://www.wikidata.org/wiki/Q417379', 'display_name': 'Post-transcriptional modification', 'level': 5, 'score': 0.48376727}, {'id': 'https://openalex.org/C108190873', 'wikidata': 'https://www.wikidata.org/wiki/Q6395811', 'display_name': 'Nuclease protection assay', 'level': 5, 'score': 0.454331}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.41277495}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.20134342}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.1251874}], 'mesh': [{'descriptor_ui': 'D004722', 'descriptor_name': 'Endoribonucleases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D029968', 'descriptor_name': 'Escherichia coli Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009694', 'descriptor_name': 'Nucleic Acid Precursors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004722', 'descriptor_name': 'Endoribonucleases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009694', 'descriptor_name': 'Nucleic Acid Precursors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009843', 'descriptor_name': 'Oligoribonucleotides', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012329', 'descriptor_name': 'RNA, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012329', 'descriptor_name': 'RNA, Bacterial', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043262', 'descriptor_name': 'Ribonuclease P', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006163', 'descriptor_name': 'Ribonuclease T1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.80.14.4450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc384056', 'pdf_url': 'https://europepmc.org/articles/pmc384056?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC384056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/6192433', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc384056', 'pdf_url': 'https://europepmc.org/articles/pmc384056?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W1487552800', 'https://openalex.org/W1497895596', 'https://openalex.org/W1517227169', 'https://openalex.org/W1543686981', 'https://openalex.org/W1544445436', 'https://openalex.org/W1581724194', 'https://openalex.org/W1592065364', 'https://openalex.org/W1965714483', 'https://openalex.org/W1970300715', 'https://openalex.org/W1983204232', 'https://openalex.org/W1986904978', 'https://openalex.org/W1996356285', 'https://openalex.org/W2004114893', 'https://openalex.org/W2004406095', 'https://openalex.org/W2005450173', 'https://openalex.org/W2011103084', 'https://openalex.org/W2011979604', 'https://openalex.org/W2023588431', 'https://openalex.org/W2029681413', 'https://openalex.org/W2038707341', 'https://openalex.org/W2046901323', 'https://openalex.org/W2058337185', 'https://openalex.org/W2072468798', 'https://openalex.org/W2082217915', 'https://openalex.org/W2083133812', 'https://openalex.org/W2084845872', 'https://openalex.org/W2091340759', 'https://openalex.org/W2109473626', 'https://openalex.org/W2109818870', 'https://openalex.org/W2114624600', 'https://openalex.org/W2128744138', 'https://openalex.org/W2130025327', 'https://openalex.org/W2144047802', 'https://openalex.org/W2343975879', 'https://openalex.org/W2408736732'], 'related_works': ['https://openalex.org/W4321502456', 'https://openalex.org/W2168912093', 'https://openalex.org/W2145954098', 'https://openalex.org/W2072113030', 'https://openalex.org/W2056280943', 'https://openalex.org/W2055505335', 'https://openalex.org/W2026503668', 'https://openalex.org/W2012105278', 'https://openalex.org/W1750017366', 'https://openalex.org/W1002073993'], 'abstract_inverted_index': {'A': [0], 'precursor': [1, 39, 59], 'molecule': [2, 40, 83, 136], 'for': [3, 149], '10Sb': [4, 33, 61, 87, 121], '(M1)': [5], 'RNA,': [6], 'the': [7, 11, 32, 54, 84, 91, 114, 117, 162, 170], 'RNA': [8, 12, 34, 38, 58, 62, 119, 122, 135, 166], 'moiety': [9], 'of': [10, 86, 90, 94, 116, 133, 164], 'processing': [13, 115, 167], 'enzyme': [14], 'ribonuclease': [15], 'P': [16], '(EC': [17], '3.1.26.5),': [18], 'is': [19, 41, 123], 'accumulated': [20], 'transiently': [21], 'in': [22, 43, 47, 79, 106, 137, 169], 'an': [23, 64], 'Escherichia': [24], 'coli': [25, 172], 'strain': [26], 'containing': [27], 'a': [28, 48, 70, 82, 127, 134, 138, 146, 165], 'plasmid': [29], 'that': [30, 68, 113, 142], 'carries': [31], 'gene.': [35], 'The': [36, 57, 131], 'same': [37], 'accumulated,': [42], 'relatively': [44], 'large': [45], 'quantities,': [46], 'temperature-sensitive': [49], 'RNase': [50, 98, 100, 103, 139, 150], 'E-': [51, 140], 'mutant': [52, 141], 'at': [53], 'nonpermissive': [55], 'temperature.': [56], 'includes': [60], 'and': [63, 73, 156], 'extra': [65], "3'": [66], 'fragment': [67], 'contains': [69], 'termination': [71], 'stem': [72], 'loop.': [74], 'It': [75], 'can': [76, 157], 'be': [77, 158], 'processed': [78], 'vitro': [80], 'to': [81, 120], 'size': [85], 'RNA.': [88], 'None': [89], 'four': [92], 'endoribonucleases': [93], 'E.': [95, 171], 'coli--RNase': [96], 'III,': [97], 'E,': [99], 'F,': [101], 'or': [102], 'P--takes': [104], 'part': [105], 'this': [107], 'cleavage': [108, 147], 'reaction.': [109], 'Therefore,': [110], 'we': [111], 'suggest': [112], 'precursor-10Sb': [118], 'carried': [124], 'out': [125], 'by': [126, 160], 'thus-far': [128], 'unidentified': [129], 'endoribonuclease.': [130], 'accumulation': [132], 'does': [143], 'not': [144], 'contain': [145], 'site': [148], 'E': [151], 'has': [152], 'been': [153], 'encountered': [154], 'previously': [155], 'explained': [159], 'assuming': [161], 'existence': [163], 'complex': [168], 'cell.': [173]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2026503668', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-16T12:52:09.189032', 'created_date': '2016-06-24'}