Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2118292221', 'doi': 'https://doi.org/10.1124/dmd.31.4.452', 'title': 'Glucuronides of Tea Catechins: Enzymology of Biosynthesis and Biological Activities', 'display_name': 'Glucuronides of Tea Catechins: Enzymology of Biosynthesis and Biological Activities', 'publication_year': 2003, 'publication_date': '2003-04-01', 'ids': {'openalex': 'https://openalex.org/W2118292221', 'doi': 'https://doi.org/10.1124/dmd.31.4.452', 'mag': '2118292221', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12642472'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1124/dmd.31.4.452', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S145039780', 'display_name': 'Drug Metabolism and Disposition', 'issn_l': '0090-9556', 'issn': ['0090-9556', '1521-009X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316283', 'host_organization_name': 'American Society for Pharmacology and Experimental Therapeutics', 'host_organization_lineage': ['https://openalex.org/P4310316283'], 'host_organization_lineage_names': ['American Society for Pharmacology and Experimental Therapeutics'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5041576429', 'display_name': 'Hongcheng Lu', 'orcid': 'https://orcid.org/0000-0003-0414-4768'}, 'institutions': [{'id': 'https://openalex.org/I102322142', 'display_name': 'Rutgers, The State University of New Jersey', 'ror': 'https://ror.org/05vt9qd57', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I102322142']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hong Lu', 'raw_affiliation_strings': ['Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers the State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers the State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA.', 'institution_ids': ['https://openalex.org/I102322142']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067195830', 'display_name': 'Xiaofeng Meng', 'orcid': 'https://orcid.org/0000-0002-3750-6342'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiaofeng Meng', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100404419', 'display_name': 'Chuan Li', 'orcid': 'https://orcid.org/0000-0002-4381-3891'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chuan Li', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049058017', 'display_name': 'Shengmin Sang', 'orcid': 'https://orcid.org/0000-0002-5005-3616'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Shengmin Sang', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080864786', 'display_name': 'Christopher Patten', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Christopher Patten', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044281345', 'display_name': 'Shuqun Sheng', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Shuqun Sheng', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065732535', 'display_name': 'Jungil Hong', 'orcid': 'https://orcid.org/0000-0002-3878-6059'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jungil Hong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012126213', 'display_name': 'Naisheng Bai', 'orcid': 'https://orcid.org/0000-0001-6056-9192'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Naisheng Bai', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026120117', 'display_name': 'Bożena Winnik', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bozena Winnik', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036062527', 'display_name': 'Chi‐Tang Ho', 'orcid': 'https://orcid.org/0000-0001-8273-2085'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chi-Tang Ho', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086188593', 'display_name': 'Chung S. Yang', 'orcid': 'https://orcid.org/0000-0001-6713-4837'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chung S Yang', 'raw_affiliation_strings': [], 'affiliations': []}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 8.757, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 218, 'citation_normalized_percentile': {'value': 0.999863, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '31', 'issue': '4', 'first_page': '452', 'last_page': '461'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11411', 'display_name': 'Health Effects of Tea Polyphenols', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11411', 'display_name': 'Health Effects of Tea Polyphenols', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10035', 'display_name': 'Antioxidants and Free Radicals in Health and Disease', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2704', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13817', 'display_name': 'Microbial Tannase Production and Applications', 'score': 0.9892, 'subfield': {'id': 'https://openalex.org/subfields/2402', 'display_name': 'Applied Microbiology and Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/glucuronide', 'display_name': 'Glucuronide', 'score': 0.72690123}, {'id': 'https://openalex.org/keywords/biotransformation', 'display_name': 'Biotransformation', 'score': 0.6260342}, {'id': 'https://openalex.org/keywords/catechins', 'display_name': 'Catechins', 'score': 0.51051}], 'concepts': [{'id': 'https://openalex.org/C2779907587', 'wikidata': 'https://www.wikidata.org/wiki/Q14901439', 'display_name': 'Glucuronidation', 'level': 4, 'score': 0.9497032}, {'id': 'https://openalex.org/C2779186261', 'wikidata': 'https://www.wikidata.org/wiki/Q137786', 'display_name': 'Glucuronide', 'level': 3, 'score': 0.72690123}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.67232645}, {'id': 'https://openalex.org/C87644729', 'wikidata': 'https://www.wikidata.org/wiki/Q547502', 'display_name': 'Microsome', 'level': 3, 'score': 0.63553506}, {'id': 'https://openalex.org/C27881333', 'wikidata': 'https://www.wikidata.org/wiki/Q864895', 'display_name': 'Biotransformation', 'level': 3, 'score': 0.6260342}, {'id': 'https://openalex.org/C2779431889', 'wikidata': 'https://www.wikidata.org/wiki/Q415007', 'display_name': 'Catechin', 'level': 4, 'score': 0.58809745}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.57723916}, {'id': 'https://openalex.org/C2777882243', 'wikidata': 'https://www.wikidata.org/wiki/Q11090', 'display_name': 'Small intestine', 'level': 2, 'score': 0.48913768}, {'id': 'https://openalex.org/C119795356', 'wikidata': 'https://www.wikidata.org/wiki/Q407801', 'display_name': 'Isozyme', 'level': 3, 'score': 0.46254203}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.43639332}, {'id': 'https://openalex.org/C116073593', 'wikidata': 'https://www.wikidata.org/wiki/Q864491', 'display_name': 'Biological activity', 'level': 3, 'score': 0.41926432}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.37238508}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.32148537}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.31811786}, {'id': 'https://openalex.org/C70899900', 'wikidata': 'https://www.wikidata.org/wiki/Q290439', 'display_name': 'Polyphenol', 'level': 3, 'score': 0.28926837}], 'mesh': [{'descriptor_ui': 'D002392', 'descriptor_name': 'Catechin', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D002392', 'descriptor_name': 'Catechin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D014453', 'descriptor_name': 'Glucuronosyltransferase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008861', 'descriptor_name': 'Microsomes', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D011837', 'descriptor_name': 'Radiation-Protective Agents', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016718', 'descriptor_name': 'Arachidonic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016718', 'descriptor_name': 'Arachidonic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002392', 'descriptor_name': 'Catechin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002392', 'descriptor_name': 'Catechin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002392', 'descriptor_name': 'Catechin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002851', 'descriptor_name': 'Chromatography, High Pressure Liquid', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D002851', 'descriptor_name': 'Chromatography, High Pressure Liquid', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': False}, {'descriptor_ui': 'D002851', 'descriptor_name': 'Chromatography, High Pressure Liquid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008401', 'descriptor_name': 'Gas Chromatography-Mass Spectrometry', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': False}, {'descriptor_ui': 'D008401', 'descriptor_name': 'Gas Chromatography-Mass Spectrometry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D008401', 'descriptor_name': 'Gas Chromatography-Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014453', 'descriptor_name': 'Glucuronosyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007313', 'descriptor_name': 'Insecta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007413', 'descriptor_name': 'Intestinal Mucosa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007422', 'descriptor_name': 'Intestines', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D007422', 'descriptor_name': 'Intestines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008815', 'descriptor_name': 'Mice, Inbred Strains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008861', 'descriptor_name': 'Microsomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008861', 'descriptor_name': 'Microsomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011837', 'descriptor_name': 'Radiation-Protective Agents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011837', 'descriptor_name': 'Radiation-Protective Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011837', 'descriptor_name': 'Radiation-Protective Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1124/dmd.31.4.452', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S145039780', 'display_name': 'Drug Metabolism and Disposition', 'issn_l': '0090-9556', 'issn': ['0090-9556', '1521-009X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316283', 'host_organization_name': 'American Society for Pharmacology and Experimental Therapeutics', 'host_organization_lineage': ['https://openalex.org/P4310316283'], 'host_organization_lineage_names': ['American Society for Pharmacology and Experimental Therapeutics'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12642472', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1566984855', 'https://openalex.org/W1856681512', 'https://openalex.org/W1887275565', 'https://openalex.org/W1923734449', 'https://openalex.org/W1943747111', 'https://openalex.org/W1967320117', 'https://openalex.org/W1968127015', 'https://openalex.org/W1975764483', 'https://openalex.org/W1980094999', 'https://openalex.org/W1983989974', 'https://openalex.org/W1996657525', 'https://openalex.org/W2028582213', 'https://openalex.org/W2028731895', 'https://openalex.org/W2033643259', 'https://openalex.org/W2034747473', 'https://openalex.org/W2036858611', 'https://openalex.org/W2040946169', 'https://openalex.org/W2065853716', 'https://openalex.org/W2070000009', 'https://openalex.org/W2071878521', 'https://openalex.org/W2075380466', 'https://openalex.org/W2077521706', 'https://openalex.org/W2082154731', 'https://openalex.org/W2092778704', 'https://openalex.org/W2100081585', 'https://openalex.org/W2102513234', 'https://openalex.org/W2105546629', 'https://openalex.org/W2110478964', 'https://openalex.org/W2110482855', 'https://openalex.org/W2121689079', 'https://openalex.org/W2125565767', 'https://openalex.org/W2125767380', 'https://openalex.org/W2126433477', 'https://openalex.org/W2128982562', 'https://openalex.org/W2131721815', 'https://openalex.org/W2136865018', 'https://openalex.org/W2142693119', 'https://openalex.org/W2147593455', 'https://openalex.org/W2155360721', 'https://openalex.org/W2162854127', 'https://openalex.org/W2164533609', 'https://openalex.org/W2165669901', 'https://openalex.org/W2169693919', 'https://openalex.org/W2171767046', 'https://openalex.org/W2405982724', 'https://openalex.org/W2614443566', 'https://openalex.org/W4251772538'], 'related_works': ['https://openalex.org/W4251122884', 'https://openalex.org/W2902161651', 'https://openalex.org/W2884261249', 'https://openalex.org/W2127974033', 'https://openalex.org/W2093461594', 'https://openalex.org/W2066120982', 'https://openalex.org/W2061639233', 'https://openalex.org/W2059503272', 'https://openalex.org/W2023516669', 'https://openalex.org/W136036310'], 'abstract_inverted_index': {'(-)-Epigallocatechin': [0], 'gallate': [1], '(EGCG)': [2], 'and': [3, 13, 25, 30, 33, 40, 49, 54, 128, 135, 174, 191, 213], '(-)-epigallocatechin': [4], '(EGC)': [5], 'are': [6], 'major': [7, 66], 'green': [8], 'tea': [9, 217], 'catechins': [10], 'with': [11, 140, 155], 'antioxidant': [12], 'anticancer': [14], 'activities.': [15], 'In': [16], 'this': [17], 'study,': [18], 'we': [19], 'characterized': [20], 'the': [21, 60, 65, 81, 115, 147, 170, 182, 194, 211], 'glucuronidation': [22, 100, 171], 'of': [23, 101, 108, 172, 177, 184, 196, 216], 'EGCG': [24, 48, 67, 151, 173], 'EGC': [26, 50, 102], 'in': [27, 44, 70, 169, 188, 192], 'human,': [28], 'mouse,': [29], 'rat': [31, 92, 95, 124, 127], 'microsomes': [32], 'by': [34], 'nine': [35], 'different': [36], 'human': [37, 89, 121, 201], 'UGT': [38], '1A': [39], '2B': [41], 'isozymes': [42], 'expressed': [43], 'insect': [45], 'cells.': [46, 204], 'Six': [47], 'glucuronides': [51, 180], 'were': [52, 57], 'biosynthesized,': [53], 'their': [55, 185], 'structures': [56], 'identified': [58], 'for': [59, 77, 112, 150, 209], 'first': [61], 'time.': [62], '(-)-EGCG-4"-O-glucuronide': [63, 78], 'was': [64, 103], 'glucuronide': [68], 'formed': [69], 'all': [71], 'incubations.': [72], 'The': [73, 98, 110], 'catalytic': [74], 'efficiency': [75], '(V(max)/K(m))': [76], 'formation': [79], 'followed': [80, 114], 'order:': [82, 117], 'mouse': [83, 86, 118, 129], 'intestine': [84], '>': [85, 88, 91, 120, 123, 126], 'liver': [87, 90, 93, 119, 122, 125], '>>': [94], 'small': [96, 130], 'intestine.': [97, 131], 'UGT-catalyzed': [99], 'much': [104], 'lower': [105], 'than': [106, 165], 'that': [107], 'EGCG.': [109, 141], 'V(max)/K(m)': [111, 149], "(-)-EGC-3'-O-glucuronide": [113], 'following': [116], 'Human': [132], 'UGT1A1,': [133], '1A8,': [134], '1A9': [136], 'had': [137, 146], 'high': [138], 'activities': [139, 183, 215], 'UGT1A8,': [142], 'an': [143], 'intestine-specific': [144], 'UGT,': [145], 'highest': [148], 'but': [152], 'low': [153], 'activity': [154], 'EGC.': [156, 175], 'Mice': [157], 'appeared': [158], 'to': [159, 163, 167], 'be': [160], 'more': [161], 'similar': [162], 'humans': [164, 168], 'rats': [166], 'Some': [176], 'these': [178], 'catechin': [179], 'retained': [181], 'parent': [186], 'compounds': [187], 'radical': [189], 'scavenging': [190], 'inhibiting': [193], 'release': [195], 'arachidonic': [197], 'acid': [198], 'from': [199], 'HT-29': [200], 'colon': [202], 'cancer': [203], 'These': [205], 'results': [206], 'provide': [207], 'foundations': [208], 'understanding': [210], 'biotransformation': [212], 'biological': [214], 'catechins.': [218]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2118292221', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 11}, {'year': 2013, 'cited_by_count': 19}, {'year': 2012, 'cited_by_count': 14}], 'updated_date': '2024-08-13T18:20:32.543500', 'created_date': '2016-06-24'}