Publication Information

{'id': 'https://openalex.org/W2116677682', 'doi': None, 'title': 'Diagnostic value of anti-cyclic citrullinated Peptide antibody in patients with rheumatoid arthritis.', 'display_name': 'Diagnostic value of anti-cyclic citrullinated Peptide antibody in patients with rheumatoid arthritis.', 'publication_year': 2003, 'publication_date': '2003-07-01', 'ids': {'openalex': 'https://openalex.org/W2116677682', 'mag': '2116677682', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12858440'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12858440', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073523669', 'display_name': 'Xiaofeng Zeng', 'orcid': 'https://orcid.org/0000-0002-3883-2318'}, 'institutions': [{'id': 'https://openalex.org/I2801228662', 'display_name': 'Peking Union Medical College Hospital', 'ror': 'https://ror.org/04jztag35', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801228662']}, {'id': 'https://openalex.org/I200296433', 'display_name': 'Chinese Academy of Medical Sciences & Peking Union Medical College', 'ror': 'https://ror.org/02drdmm93', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I200296433']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaofeng Zeng', 'raw_affiliation_strings': ['Department of Rheumatology, Chinese Academy of Medical Science, Peking Union Medical College Hospital, Beijing, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Rheumatology, Chinese Academy of Medical Science, Peking Union Medical College Hospital, Beijing, China.', 'institution_ids': ['https://openalex.org/I2801228662', 'https://openalex.org/I200296433']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045904301', 'display_name': 'Maixing Ai', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Maixing Ai', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042081356', 'display_name': 'Xinping Tian', 'orcid': 'https://orcid.org/0000-0002-1511-7952'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xinping Tian', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090777039', 'display_name': 'Xiaodan Gan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiaodan Gan', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113821982', 'display_name': 'Yan‐Ping Shi', 'orcid': 'https://orcid.org/0000-0001-6517-9556'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yanping Shi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039921817', 'display_name': 'Qinfang Song', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Qinfang Song', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103334731', 'display_name': 'Fu-lin Tang', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Fulin Tang', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 10.448, 'has_fulltext': False, 'cited_by_count': 88, 'citation_normalized_percentile': {'value': 0.89031, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '30', 'issue': '7', 'first_page': '1451', 'last_page': '5'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis Research and Therapies', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rheumatoid-factor', 'display_name': 'Rheumatoid factor', 'score': 0.6549691}, {'id': 'https://openalex.org/keywords/aka', 'display_name': 'AKA', 'score': 0.55731314}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.91254187}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.8167484}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.7346237}, {'id': 'https://openalex.org/C2776232647', 'wikidata': 'https://www.wikidata.org/wiki/Q702883', 'display_name': 'Rheumatoid factor', 'level': 3, 'score': 0.6549691}, {'id': 'https://openalex.org/C121158502', 'wikidata': 'https://www.wikidata.org/wiki/Q4652161', 'display_name': 'AKA', 'level': 2, 'score': 0.55731314}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5371739}, {'id': 'https://openalex.org/C2777077863', 'wikidata': 'https://www.wikidata.org/wiki/Q170990', 'display_name': 'Arthritis', 'level': 2, 'score': 0.43913656}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3838849}, {'id': 'https://openalex.org/C161191863', 'wikidata': 'https://www.wikidata.org/wiki/Q199655', 'display_name': 'Library science', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D001323', 'descriptor_name': 'Autoantibodies', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D002956', 'descriptor_name': 'Citrulline', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D010456', 'descriptor_name': 'Peptides, Cyclic', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000974', 'descriptor_name': 'Antibodies, Antinuclear', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D000974', 'descriptor_name': 'Antibodies, Antinuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001323', 'descriptor_name': 'Autoantibodies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002956', 'descriptor_name': 'Citrulline', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015804', 'descriptor_name': 'HLA-DR4 Antigen', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015804', 'descriptor_name': 'HLA-DR4 Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007633', 'descriptor_name': 'Keratins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007633', 'descriptor_name': 'Keratins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010456', 'descriptor_name': 'Peptides, Cyclic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012372', 'descriptor_name': 'ROC Curve', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012217', 'descriptor_name': 'Rheumatoid Factor', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D012217', 'descriptor_name': 'Rheumatoid Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12858440', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.72, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4228999244', 'https://openalex.org/W3029502969', 'https://openalex.org/W2392237670', 'https://openalex.org/W2372970583', 'https://openalex.org/W2355285032', 'https://openalex.org/W2259637392', 'https://openalex.org/W2168304747', 'https://openalex.org/W2116677682', 'https://openalex.org/W2003275497', 'https://openalex.org/W1978711157'], 'abstract_inverted_index': {'To': [0], 'explore': [1], 'the': [2, 86], 'diagnostic': [3, 195], 'value': [4], 'of': [5, 76, 117, 168], 'anti-cyclic': [6], 'citrullinated': [7, 22], 'peptide': [8, 23], 'antibody': [9, 31, 58, 83, 111, 119, 130, 143, 188], '(anti-CCP)': [10], 'detected': [11, 33], 'by': [12, 34, 113], 'ELISA': [13, 35], 'in': [14, 36, 70, 127, 155], 'patients': [15, 38, 91, 156], 'with': [16, 39, 42, 50, 81, 92, 96, 103, 122, 132, 157, 172, 185], 'rheumatoid': [17, 60], 'arthritis': [18], '(RA).The': [19], 'synthesized': [20], 'cyclic': [21], 'was': [24, 32, 120, 160], 'used': [25], 'as': [26, 162, 192], 'substrate': [27], 'for': [28, 197], 'ELISA.': [29, 114], 'Anti-CCP': [30, 129, 170, 187], '191': [37], 'RA,': [40, 47, 93], '132': [41], 'rheumatic': [43, 98], 'diseases': [44, 105], 'other': [45, 97], 'than': [46], 'and': [48, 63, 100, 136, 159, 176], '98': [49], 'nonrheumatic': [51, 104], 'diseases.': [52], 'The': [53, 74, 115], 'antiperinuclear': [54], 'factor': [55, 61], '(APF),': [56], 'anti-keratin': [57], '(AKA),': [59], '(RF),': [62], 'HLA-DR4': [64, 137, 177], 'gene': [65, 138, 178], 'complex': [66], 'were': [67, 79, 106], 'also': [68], 'tested': [69], 'each': [71], 'RA': [72, 158], 'patient.': [73], 'results': [75], 'these': [77], 'tests': [78], 'compared': [80], 'anti-CCP': [82, 110, 118, 142], 'to': [84, 108, 166], 'examine': [85], 'correlation': [87], 'between': [88], 'them.Ninety': [89], '(47.1%)': [90, 149], '4': [94], '(3.0%)': [95], 'diseases,': [99], '2': [101], '(2.0%)': [102], 'found': [107, 161], 'be': [109, 190], 'positive': [112], 'sensitivity': [116, 148], '47.1%,': [121], 'a': [123, 146, 151, 163, 193], 'high': [124, 152], 'specificity': [125, 153], '(97.4%)': [126, 154], 'RA.': [128, 169, 198], 'correlated': [131, 171], 'APF,': [133, 173], 'AKA,': [134, 174], 'RF,': [135, 175], 'complex.A': [139], 'new': [140, 194], 'modified': [141], 'test': [144], 'had': [145], 'moderate': [147], 'but': [150, 180], 'valuable': [164], 'supplement': [165], 'diagnosis': [167], 'complex,': [179], 'did': [181], 'not': [182], 'completely': [183], 'overlap': [184], 'them.': [186], 'could': [189], 'regarded': [191], 'marker': [196]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2116677682', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-24T14:06:22.732946', 'created_date': '2016-06-24'}