Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2115317952', 'doi': 'https://doi.org/10.1200/jco.2009.26.7906', 'title': 'Evidence and Practice Regarding the Role for CYP2D6 Inhibition in Decisions About Tamoxifen Therapy', 'display_name': 'Evidence and Practice Regarding the Role for CYP2D6 Inhibition in Decisions About Tamoxifen Therapy', 'publication_year': 2010, 'publication_date': '2010-02-02', 'ids': {'openalex': 'https://openalex.org/W2115317952', 'doi': 'https://doi.org/10.1200/jco.2009.26.7906', 'mag': '2115317952', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20124162'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1200/jco.2009.26.7906', 'pdf_url': 'https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2009.26.7906?role=tab', 'source': {'id': 'https://openalex.org/S15137598', 'display_name': 'Journal of Clinical Oncology', 'issn_l': '0732-183X', 'issn': ['0732-183X', '1527-7755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2009.26.7906?role=tab', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5039413618', 'display_name': 'Timothy L. Lash', 'orcid': 'https://orcid.org/0000-0002-5240-5195'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}, {'id': 'https://openalex.org/I2802335433', 'display_name': 'Aarhus University Hospital', 'ror': 'https://ror.org/040r8fr65', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802335433']}], 'countries': ['DK', 'US'], 'is_corresponding': False, 'raw_author_name': 'Timothy L. Lash', 'raw_affiliation_strings': ['Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; Section of Geriatrics, Department of Medicine, Boston University School of Medicine; and Epidemiology Department, Boston University School of Public Health, Boston, MA'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; Section of Geriatrics, Department of Medicine, Boston University School of Medicine; and Epidemiology Department, Boston University School of Public Health, Boston, MA', 'institution_ids': ['https://openalex.org/I111088046', 'https://openalex.org/I2802335433']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006333456', 'display_name': 'Carol L. Rosenberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Carol L. Rosenberg', 'raw_affiliation_strings': ['Section of Hematology-Medical Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA.'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology-Medical Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA.', 'institution_ids': ['https://openalex.org/I111088046']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.696629, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '28', 'issue': '8', 'first_page': '1273', 'last_page': '1275'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11752', 'display_name': 'Cancer Treatment and Pharmacology', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8986732}, {'id': 'https://openalex.org/C2777176818', 'wikidata': 'https://www.wikidata.org/wiki/Q412178', 'display_name': 'Tamoxifen', 'level': 4, 'score': 0.8266722}, {'id': 'https://openalex.org/C33664856', 'wikidata': 'https://www.wikidata.org/wiki/Q3271142', 'display_name': 'CYP2D6', 'level': 4, 'score': 0.52442515}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5053947}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3935917}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.37110305}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.3268348}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.22920129}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.21364719}, {'id': 'https://openalex.org/C526171541', 'wikidata': 'https://www.wikidata.org/wiki/Q407693', 'display_name': 'Cytochrome P450', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018931', 'descriptor_name': 'Antineoplastic Agents, Hormonal', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D019389', 'descriptor_name': 'Cytochrome P-450 CYP2D6', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D065690', 'descriptor_name': 'Cytochrome P-450 CYP2D6 Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013629', 'descriptor_name': 'Tamoxifen', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D018931', 'descriptor_name': 'Antineoplastic Agents, Hormonal', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D018931', 'descriptor_name': 'Antineoplastic Agents, Hormonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019389', 'descriptor_name': 'Cytochrome P-450 CYP2D6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005820', 'descriptor_name': 'Genetic Testing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057285', 'descriptor_name': 'Precision Medicine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013629', 'descriptor_name': 'Tamoxifen', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013629', 'descriptor_name': 'Tamoxifen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1200/jco.2009.26.7906', 'pdf_url': 'https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2009.26.7906?role=tab', 'source': {'id': 'https://openalex.org/S15137598', 'display_name': 'Journal of Clinical Oncology', 'issn_l': '0732-183X', 'issn': ['0732-183X', '1527-7755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20124162', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1200/jco.2009.26.7906', 'pdf_url': 'https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2009.26.7906?role=tab', 'source': {'id': 'https://openalex.org/S15137598', 'display_name': 'Journal of Clinical Oncology', 'issn_l': '0732-183X', 'issn': ['0732-183X', '1527-7755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.55, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W1494460083', 'https://openalex.org/W1595502980', 'https://openalex.org/W1631027698', 'https://openalex.org/W1907577058', 'https://openalex.org/W1961026612', 'https://openalex.org/W1964945591', 'https://openalex.org/W1965026061', 'https://openalex.org/W1965111408', 'https://openalex.org/W1970531647', 'https://openalex.org/W1976673997', 'https://openalex.org/W1977587162', 'https://openalex.org/W1981125500', 'https://openalex.org/W1991118471', 'https://openalex.org/W2001333277', 'https://openalex.org/W2002041504', 'https://openalex.org/W2015092588', 'https://openalex.org/W2017210748', 'https://openalex.org/W2035025788', 'https://openalex.org/W2035963345', 'https://openalex.org/W2036669175', 'https://openalex.org/W2044190863', 'https://openalex.org/W2044308633', 'https://openalex.org/W2047246104', 'https://openalex.org/W2048508323', 'https://openalex.org/W2055259850', 'https://openalex.org/W2061608218', 'https://openalex.org/W2063315896', 'https://openalex.org/W2063345843', 'https://openalex.org/W2074335085', 'https://openalex.org/W2080631897', 'https://openalex.org/W2085464372', 'https://openalex.org/W2086678449', 'https://openalex.org/W2088585390', 'https://openalex.org/W2092589313', 'https://openalex.org/W2111714917', 'https://openalex.org/W2117305280', 'https://openalex.org/W2122299471', 'https://openalex.org/W2127660956', 'https://openalex.org/W2128879861', 'https://openalex.org/W2130377362', 'https://openalex.org/W2147099166', 'https://openalex.org/W2151950513', 'https://openalex.org/W2154444846', 'https://openalex.org/W2155803397', 'https://openalex.org/W2167785958', 'https://openalex.org/W2172254302', 'https://openalex.org/W2327728766', 'https://openalex.org/W2518355778', 'https://openalex.org/W3198835821', 'https://openalex.org/W4249835573', 'https://openalex.org/W4256354773'], 'related_works': ['https://openalex.org/W2162625234', 'https://openalex.org/W2138151507', 'https://openalex.org/W2113225995', 'https://openalex.org/W2073973349', 'https://openalex.org/W2069469265', 'https://openalex.org/W2013479777', 'https://openalex.org/W1994401414', 'https://openalex.org/W1993646007', 'https://openalex.org/W1980756636', 'https://openalex.org/W1514995717'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2115317952', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2025-01-12T07:14:14.742818', 'created_date': '2016-06-24'}