Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2112045924', 'doi': 'https://doi.org/10.1136/jcp.31.9.827', 'title': 'A comparison of complement fixation, indirect immunofluorescence for viral late antigens, and anti-complement immunofluorescence tests for the detection of cytomegalovirus specific serum antibodies.', 'display_name': 'A comparison of complement fixation, indirect immunofluorescence for viral late antigens, and anti-complement immunofluorescence tests for the detection of cytomegalovirus specific serum antibodies.', 'publication_year': 1978, 'publication_date': '1978-09-01', 'ids': {'openalex': 'https://openalex.org/W2112045924', 'doi': 'https://doi.org/10.1136/jcp.31.9.827', 'mag': '2112045924', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/213450', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1145423'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/jcp.31.9.827', 'pdf_url': 'https://jcp.bmj.com/content/jclinpath/31/9/827.full.pdf', 'source': {'id': 'https://openalex.org/S37362813', 'display_name': 'Journal of Clinical Pathology', 'issn_l': '0021-9746', 'issn': ['0021-9746', '1472-4146'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jcp.bmj.com/content/jclinpath/31/9/827.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027717859', 'display_name': 'Paul Griffiths', 'orcid': 'https://orcid.org/0000-0001-9317-5915'}, 'institutions': [{'id': 'https://openalex.org/I1307195382', 'display_name': "St Bartholomew's Hospital", 'ror': 'https://ror.org/00nh9x179', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307195382', 'https://openalex.org/I225661044']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'P D Griffiths', 'raw_affiliation_strings': ["From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK"], 'affiliations': [{'raw_affiliation_string': "From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK", 'institution_ids': ['https://openalex.org/I1307195382']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011633906', 'display_name': 'K. J. Buie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1307195382', 'display_name': "St Bartholomew's Hospital", 'ror': 'https://ror.org/00nh9x179', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307195382', 'https://openalex.org/I225661044']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'K J Buie', 'raw_affiliation_strings': ["From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK"], 'affiliations': [{'raw_affiliation_string': "From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK", 'institution_ids': ['https://openalex.org/I1307195382']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025037807', 'display_name': 'R. B. Heath', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1307195382', 'display_name': "St Bartholomew's Hospital", 'ror': 'https://ror.org/00nh9x179', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307195382', 'https://openalex.org/I225661044']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'R B Heath', 'raw_affiliation_strings': ["From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK"], 'affiliations': [{'raw_affiliation_string': "From the Department of Virology, St. Bartholomew's Hospital, London ECIA 7BE, UK", 'institution_ids': ['https://openalex.org/I1307195382']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.664, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.785941, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '31', 'issue': '9', 'first_page': '827', 'last_page': '831'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11725', 'display_name': 'Immunodeficiency and Autoimmune Disorders', 'score': 0.9767, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11660', 'display_name': 'Blood groups and transfusion', 'score': 0.9672, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/immunofluorescence', 'display_name': 'Immunofluorescence', 'score': 0.9036073}, {'id': 'https://openalex.org/keywords/complement-fixation-test', 'display_name': 'Complement fixation test', 'score': 0.88844967}, {'id': 'https://openalex.org/keywords/cytomegalovirus', 'display_name': 'Cytomegalovirus', 'score': 0.67073506}], 'concepts': [{'id': 'https://openalex.org/C2778236600', 'wikidata': 'https://www.wikidata.org/wiki/Q592324', 'display_name': 'Immunofluorescence', 'level': 3, 'score': 0.9036073}, {'id': 'https://openalex.org/C152669594', 'wikidata': 'https://www.wikidata.org/wiki/Q904197', 'display_name': 'Complement fixation test', 'level': 4, 'score': 0.88844967}, {'id': 'https://openalex.org/C2984894117', 'wikidata': 'https://www.wikidata.org/wiki/Q592324', 'display_name': 'Indirect immunofluorescence', 'level': 3, 'score': 0.7990751}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.7053904}, {'id': 'https://openalex.org/C2777732132', 'wikidata': 'https://www.wikidata.org/wiki/Q6946', 'display_name': 'Cytomegalovirus', 'level': 5, 'score': 0.67073506}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.62688625}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.49773672}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.48993415}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42761588}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.39282146}, {'id': 'https://openalex.org/C45189115', 'wikidata': 'https://www.wikidata.org/wiki/Q502159', 'display_name': 'Serology', 'level': 3, 'score': 0.27415377}, {'id': 'https://openalex.org/C2776409557', 'wikidata': 'https://www.wikidata.org/wiki/Q149348', 'display_name': 'Herpesviridae', 'level': 4, 'score': 0.26361609}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.15123409}], 'mesh': [{'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000918', 'descriptor_name': 'Antibody Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003168', 'descriptor_name': 'Complement Fixation Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/jcp.31.9.827', 'pdf_url': 'https://jcp.bmj.com/content/jclinpath/31/9/827.full.pdf', 'source': {'id': 'https://openalex.org/S37362813', 'display_name': 'Journal of Clinical Pathology', 'issn_l': '0021-9746', 'issn': ['0021-9746', '1472-4146'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1145423', 'pdf_url': 'https://europepmc.org/articles/pmc1145423?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1145423', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/213450', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/jcp.31.9.827', 'pdf_url': 'https://jcp.bmj.com/content/jclinpath/31/9/827.full.pdf', 'source': {'id': 'https://openalex.org/S37362813', 'display_name': 'Journal of Clinical Pathology', 'issn_l': '0021-9746', 'issn': ['0021-9746', '1472-4146'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 13, 'referenced_works': ['https://openalex.org/W1518170804', 'https://openalex.org/W1601818593', 'https://openalex.org/W1892287215', 'https://openalex.org/W1973841847', 'https://openalex.org/W2018199693', 'https://openalex.org/W2059384046', 'https://openalex.org/W2080479114', 'https://openalex.org/W2130696479', 'https://openalex.org/W2158943413', 'https://openalex.org/W2169804377', 'https://openalex.org/W2313291889', 'https://openalex.org/W2336657120', 'https://openalex.org/W2408717778'], 'related_works': ['https://openalex.org/W4591787', 'https://openalex.org/W2419378302', 'https://openalex.org/W2415802599', 'https://openalex.org/W2413684927', 'https://openalex.org/W2133249119', 'https://openalex.org/W2112045924', 'https://openalex.org/W2041385092', 'https://openalex.org/W2022050737', 'https://openalex.org/W1875514548', 'https://openalex.org/W1736743594'], 'abstract_inverted_index': {'It': [0], 'was': [1, 39, 54, 58], 'shown': [2], 'that,': [3], 'on': [4], 'average,': [5], 'the': [6, 9, 14, 44, 51, 70, 84, 89, 95, 111, 115], 'titres': [7], 'of': [8, 74, 88, 94, 107, 114, 126, 128], 'sera': [10, 66, 78, 96], 'obtained': [11, 34], 'by': [12, 35, 61], 'both': [13], 'anti-complement': [15], 'immunofluorescence': [16, 20, 116], '(ACIF)': [17], 'and': [18, 47], 'indirect': [19], 'for': [21, 69], 'viral': [22], 'late': [23], 'antigens': [24], '(IFA-LA)': [25], 'procedures': [26, 117], 'were': [27, 67], 'approximately': [28], 'eight': [29], 'times': [30], 'higher': [31], 'than': [32], 'those': [33], 'complement': [36], 'fixation.': [37], 'There': [38], 'no': [40], 'significant': [41], 'difference': [42], 'between': [43], 'mean': [45], 'ACIF': [46], 'IFA-LA': [48], 'titres,': [49], 'but': [50], 'former': [52], 'method': [53], 'preferred': [55], 'because': [56], 'it': [57], 'not': [59, 119], 'affected': [60], 'non-specific': [62], 'staining.': [63], 'When': [64], '406': [65], 'screened': [68], 'presence': [71], 'or': [72], 'absence': [73], 'antibodies,': [75], 'only': [76], 'five': [77], '(1.2%)': [79], 'gave': [80], 'discordant': [81], 'results': [82], 'with': [83], 'three': [85], 'tests.': [86], 'None': [87], 'tests': [90], 'could': [91], 'detect': [92], 'all': [93], 'that': [97], 'contained': [98], 'specific': [99], 'antibodies': [100], 'while': [101], 'each': [102], 'test': [103], 'detected': [104], 'over': [105], '98%': [106], 'these': [108], 'sera.': [109, 131], 'Thus,': [110], 'increased': [112, 124], 'sensitivity': [113], 'did': [118], 'result': [120], 'in': [121], 'an': [122], 'appreciably': [123], 'rate': [125], 'detection': [127], 'cytomegalovirus': [129], 'seropositive': [130]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2112045924', 'counts_by_year': [], 'updated_date': '2024-12-08T04:44:08.988094', 'created_date': '2016-06-24'}