Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2108364115', 'doi': 'https://doi.org/10.1073/pnas.0505975102', 'title': 'Three-dimensional structure of human monoamine oxidase A (MAO A): Relation to the structures of rat MAO A and human MAO B', 'display_name': 'Three-dimensional structure of human monoamine oxidase A (MAO A): Relation to the structures of rat MAO A and human MAO B', 'publication_year': 2005, 'publication_date': '2005-08-29', 'ids': {'openalex': 'https://openalex.org/W2108364115', 'doi': 'https://doi.org/10.1073/pnas.0505975102', 'mag': '2108364115', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16129825', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1200291'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.0505975102', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1200291?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5005219582', 'display_name': 'Luigi De Colibus', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Luigi De Colibus', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100687082', 'display_name': 'Min Li', 'orcid': 'https://orcid.org/0000-0002-5035-1672'}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Min Li', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070368745', 'display_name': 'Claudia Binda', 'orcid': 'https://orcid.org/0000-0003-2038-9845'}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Claudia Binda', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105781861', 'display_name': 'Ariel Lustig', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Ariel Lustig', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006813426', 'display_name': 'Dale E. Edmondson', 'orcid': 'https://orcid.org/0000-0002-1304-231X'}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Dale E. Edmondson', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5017449175', 'display_name': 'Andrea Mattevi', 'orcid': 'https://orcid.org/0000-0002-9523-7128'}, 'institutions': [{'id': 'https://openalex.org/I25217355', 'display_name': 'University of Pavia', 'ror': 'https://ror.org/00s6t1f81', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I25217355']}, {'id': 'https://openalex.org/I1850255', 'display_name': 'University of Basel', 'ror': 'https://ror.org/02s6k3f65', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I1850255']}, {'id': 'https://openalex.org/I150468666', 'display_name': 'Emory University', 'ror': 'https://ror.org/03czfpz43', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I150468666']}], 'countries': ['CH', 'IT', 'US'], 'is_corresponding': False, 'raw_author_name': 'Andrea Mattevi', 'raw_affiliation_strings': ['Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics and Microbiology, University of Pavia, via Abbiategrasso 207, 27100 Pavia, Italy; Departments of Biochemistry and Chemistry, Emory University, 1510 Clifton Road, Atlanta, GA 30322; and Biozentrum, University of Basel, Klingelbergstrasse, CH-4056 Basel, Switzerland', 'institution_ids': ['https://openalex.org/I25217355', 'https://openalex.org/I1850255', 'https://openalex.org/I150468666']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.368, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 474, 'citation_normalized_percentile': {'value': 0.99998, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '102', 'issue': '36', 'first_page': '12684', 'last_page': '12689'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12688', 'display_name': 'Biological Methane Utilization and Metabolism', 'score': 0.9884, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12688', 'display_name': 'Biological Methane Utilization and Metabolism', 'score': 0.9884, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Structure and Function of G Protein-Coupled Receptors', 'score': 0.988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10085', 'display_name': "Pathophysiology of Parkinson's Disease", 'score': 0.9803, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/clorgyline', 'display_name': 'Clorgyline', 'score': 0.60501325}, {'id': 'https://openalex.org/keywords/crystal-structures', 'display_name': 'Crystal Structures', 'score': 0.494069}, {'id': 'https://openalex.org/keywords/monoamine-oxidase-a', 'display_name': 'Monoamine oxidase A', 'score': 0.43915698}, {'id': 'https://openalex.org/keywords/monoamine-oxidase-b', 'display_name': 'Monoamine oxidase B', 'score': 0.41038886}], 'concepts': [{'id': 'https://openalex.org/C2776024655', 'wikidata': 'https://www.wikidata.org/wiki/Q410867', 'display_name': 'Monoamine oxidase', 'level': 3, 'score': 0.75044435}, {'id': 'https://openalex.org/C2910293678', 'wikidata': 'https://www.wikidata.org/wiki/Q2889652', 'display_name': 'Clorgyline', 'level': 4, 'score': 0.60501325}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.46628284}, {'id': 'https://openalex.org/C114461151', 'wikidata': 'https://www.wikidata.org/wiki/Q14888415', 'display_name': 'Monoamine oxidase A', 'level': 4, 'score': 0.43915698}, {'id': 'https://openalex.org/C166940927', 'wikidata': 'https://www.wikidata.org/wiki/Q178827', 'display_name': 'Monomer', 'level': 3, 'score': 0.41885638}, {'id': 'https://openalex.org/C39398028', 'wikidata': 'https://www.wikidata.org/wiki/Q18028862', 'display_name': 'Monoamine oxidase B', 'level': 4, 'score': 0.41038886}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.36824396}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.26400298}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.10889581}, {'id': 'https://openalex.org/C521977710', 'wikidata': 'https://www.wikidata.org/wiki/Q81163', 'display_name': 'Polymer', 'level': 2, 'score': 0.07406697}], 'mesh': [{'descriptor_ui': 'D008995', 'descriptor_name': 'Monoamine Oxidase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018360', 'descriptor_name': 'Crystallography, X-Ray', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008996', 'descriptor_name': 'Monoamine Oxidase Inhibitors', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D020836', 'descriptor_name': 'Protein Structure, Quaternary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D040681', 'descriptor_name': 'Structural Homology, Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.0505975102', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1200291', 'pdf_url': 'https://europepmc.org/articles/pmc1200291?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200291', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16129825', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1200291', 'pdf_url': 'https://europepmc.org/articles/pmc1200291?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.79, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 34, 'referenced_works': ['https://openalex.org/W105860936', 'https://openalex.org/W1505938172', 'https://openalex.org/W1508638897', 'https://openalex.org/W1591987091', 'https://openalex.org/W1604115863', 'https://openalex.org/W1986191025', 'https://openalex.org/W1998004148', 'https://openalex.org/W2001641653', 'https://openalex.org/W2006676939', 'https://openalex.org/W2007487695', 'https://openalex.org/W2012516949', 'https://openalex.org/W2013083986', 'https://openalex.org/W2026520291', 'https://openalex.org/W2028231353', 'https://openalex.org/W2036247273', 'https://openalex.org/W2038840577', 'https://openalex.org/W2042324920', 'https://openalex.org/W2042471904', 'https://openalex.org/W2042740909', 'https://openalex.org/W2045731233', 'https://openalex.org/W2046204255', 'https://openalex.org/W2062963521', 'https://openalex.org/W2068720871', 'https://openalex.org/W2072465137', 'https://openalex.org/W2080528351', 'https://openalex.org/W2085457861', 'https://openalex.org/W2088842558', 'https://openalex.org/W2093781635', 'https://openalex.org/W2103794058', 'https://openalex.org/W2110893691', 'https://openalex.org/W2120586432', 'https://openalex.org/W2160294964', 'https://openalex.org/W2170813264', 'https://openalex.org/W4242482565'], 'related_works': ['https://openalex.org/W3173253085', 'https://openalex.org/W3145078020', 'https://openalex.org/W2331347510', 'https://openalex.org/W2090114150', 'https://openalex.org/W2061391031', 'https://openalex.org/W2021936798', 'https://openalex.org/W1980224852', 'https://openalex.org/W1979947721', 'https://openalex.org/W1972820477', 'https://openalex.org/W1966806496'], 'abstract_inverted_index': {'The': [0, 143], 'three-dimensional': [1], 'structure': [2, 93, 121], 'of': [3, 20, 27, 54, 63, 75, 80, 94, 106, 117, 122, 129, 136, 145, 160, 173, 205, 235], 'recombinant': [4], 'human': [5, 32], 'monoamine': [6], 'oxidase': [7], 'A': [8, 22, 30, 38, 109, 124, 175, 185, 207, 237], '(hMAO': [9, 35], 'A)': [10], 'as': [11, 45, 167], 'its': [12], 'clorgyline-inhibited': [13], 'adduct': [14], 'is': [15, 23, 39, 86, 125, 149, 203], 'described.': [16], 'Although': [17], 'the': [18, 50, 60, 92, 118, 126, 157, 161, 171, 181, 190, 193, 233], 'chain-fold': [19], 'hMAO': [21, 37, 64, 70, 96, 123, 137, 174, 184, 206], 'similar': [24], 'to': [25, 151, 165, 192], 'that': [26, 42, 89, 105, 135, 183, 202], 'rat': [28, 67, 107, 140], 'MAO': [29, 33, 68, 108, 141, 236], 'and': [31, 48, 66, 139], 'B': [34, 65, 97, 138], 'B),': [36], 'unique': [40], 'in': [41, 156, 241, 246], 'it': [43], 'crystallizes': [44], 'a': [46, 55, 76, 168, 187, 197], 'monomer': [47], 'exhibits': [49], 'solution': [51], 'hydrodynamic': [52], 'behavior': [53], 'monomeric': [56, 158, 194], 'form': [57, 62, 159, 195], 'rather': [58], 'than': [59, 88, 104], 'dimeric': [61, 191], 'A.': [69, 142, 209], "A's": [71], 'active': [72, 119], 'site': [73, 120], 'consists': [74], 'single': [77], 'hydrophobic': [78], 'cavity': [79], '≈550': [81], 'Å': [82, 99, 111], '3': [83, 100, 112], ',': [84], 'which': [85, 132], 'smaller': [87], 'determined': [90], 'from': [91, 134, 153, 189, 238], 'deprenyl-inhibited': [95], '(≈700': [98], ')': [101], 'but': [102], 'larger': [103], '(≈450': [110], ').': [113], 'An': [114], 'important': [115], 'component': [116], 'loop': [127], 'conformation': [128], 'residues': [130], '210–216,': [131], 'differs': [133], 'origin': [144], 'this': [146], 'structural': [147], 'alteration': [148], 'suggested': [150], 'result': [152], 'long-range': [154], 'interactions': [155], 'enzyme.': [162], 'In': [163], 'addition': [164], 'serving': [166], 'basis': [169], 'for': [170, 244], 'development': [172, 243], 'specific': [176, 204], 'inhibitors,': [177], 'these': [178], 'data': [179], 'support': [180], 'proposal': [182], 'involves': [186], 'change': [188], 'through': [196], 'Glu-151': [198], '→': [199], 'Lys': [200], 'mutation': [201], '[Andrès,': [208], 'M.,': [210, 212], 'Soldevila,': [211], 'Navarro,': [213], 'A.,': [214], 'Kidd,': [215], 'K.': [216], 'K.,': [217], 'Oliva,': [218], 'B.': [219], '&': [220], 'Bertranpetit,': [221], 'J.': [222], '(2004)': [223], 'Hum.': [224], 'Genet.': [225], '115,': [226], '377–386].': [227], 'These': [228], 'considerations': [229], 'put': [230], 'into': [231], 'question': [232], 'use': [234, 245], 'nonhuman': [239], 'sources': [240], 'drug': [242], 'humans.': [247]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2108364115', 'counts_by_year': [{'year': 2024, 'cited_by_count': 21}, {'year': 2023, 'cited_by_count': 36}, {'year': 2022, 'cited_by_count': 33}, {'year': 2021, 'cited_by_count': 21}, {'year': 2020, 'cited_by_count': 27}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 30}, {'year': 2017, 'cited_by_count': 15}, {'year': 2016, 'cited_by_count': 27}, {'year': 2015, 'cited_by_count': 25}, {'year': 2014, 'cited_by_count': 28}, {'year': 2013, 'cited_by_count': 26}, {'year': 2012, 'cited_by_count': 30}], 'updated_date': '2024-09-13T05:01:46.203399', 'created_date': '2016-06-24'}