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3421, 3607, 3679, 4111, 4271, 4287, 4295, 4343], 'Sklar': [558, 1434, 4272], 'P.': [559, 660, 820, 850, 868, 895, 903, 959, 1099, 1435, 2097, 2311, 2420, 2436, 2548, 3042, 3505, 3766, 3860, 4273], 'Ardlie': [560, 1436, 4274], 'K.': [561, 782, 1019, 1079, 1103, 1139, 1208, 1210, 1365, 1367, 1437, 2194, 2414, 2418, 3427, 3613, 4117, 4275], 'Patil': [562, 1438, 4276], 'N.': [563, 565, 571, 885, 945, 1021, 1439, 1441, 1447, 2464, 3174, 3257, 4277, 4279, 4285], 'Shaw': [564, 1440, 4278], 'Lane': [566, 1442, 4280], 'C.R.': [567, 1202, 1359, 1443, 4281], 'Lim': [568, 1444, 4282], 'E.P.': [569, 1445, 4283], 'Kalyanaraman': [570, 1446, 4284], 'Nemesh': [572, 1448, 4286], 'Ziaugra': [574, 737, 1054, 1450, 4288], 'L.': [575, 577, 738, 752, 768, 818, 909, 943, 1039, 1055, 1093, 1170, 1206, 1230, 1327, 1363, 1387, 1451, 1453, 1692, 1722, 1728, 1898, 1933, 1939, 2416, 2490, 2685, 2833, 2939, 2994, 3423, 3609, 3685, 4113, 4289, 4291], 'Friedland': [576, 1452, 4290], 'Rolfe': [578, 1454, 4292], 'A.': [579, 612, 658, 714, 790, 806, 840, 844, 889, 917, 941, 979, 1013, 1017, 1218, 1375, 1455, 1534, 1736, 1738, 1947, 1949, 2151, 2155, 2378, 2424, 2647, 2741, 3045, 4293], 'Warrington': [580, 1456, 4294], 'Lipshutz': [582, 1458, 4296], 'R.': [583, 710, 858, 897, 1015, 1115, 1141, 1164, 1204, 1321, 1361, 1459, 1724, 1935, 2399, 2687, 2751, 2755, 4297], 'Daley': [584, 1460, 4298], 'G.Q.': [585, 1461, 4299], 'Lander': [586, 1462, 4300], 'E.S.': [587, 1463, 4301], 'Characterization': [588, 1464, 4302], 'single-nucleotide': [590, 1466, 4304], 'coding': [593, 1469, 1572, 1705, 1791, 1911, 2003, 4147, 4307], 'regions': [594, 1470, 4148, 4308], 'genes.Nat.': [597, 1473, 4311], 'Genet.': [598, 1474, 4312], '1999;': [599, 1475, 4313], '22:': [600, 1476, 1676, 1882, 4314], '231-238Crossref': [601, 1477, 4315], 'PubMed': [602, 628, 1158, 1261, 1295, 1418, 1478, 1511, 1550, 1618, 1678, 1712, 1768, 1804, 1834, 1884, 1918, 1979, 2016, 2048, 2112, 2147, 2182, 2208, 2262, 2303, 2340, 2393, 2456, 2476, 2514, 2536, 2566, 2662, 2710, 2771, 2857, 2974, 3029, 3069, 3161, 3204, 3287, 3365, 3440, 3493, 3534, 3626, 3666, 3709, 3795, 3889, 4130, 4208, 4316, 4367], 'Scopus': [603, 629, 1159, 1262, 1296, 1419, 1479, 1512, 1551, 1619, 1679, 1713, 1769, 1805, 1835, 1885, 1919, 1980, 2017, 2049, 2113, 2183, 2209, 2263, 2304, 2341, 2394, 2457, 2477, 2515, 2537, 2567, 2663, 2711, 2772, 2858, 2975, 3030, 3070, 3162, 3205, 3288, 3366, 3441, 3494, 3535, 3627, 3667, 3710, 3796, 3890, 4131, 4209, 4317, 4368], '(1570)': [604, 1480, 4318], 'Google': [605, 631, 1161, 1264, 1298, 1421, 1481, 1514, 1553, 1621, 1681, 1715, 1771, 1807, 1837, 1887, 1921, 1982, 2019, 2051, 2115, 2148, 2185, 2211, 2265, 2306, 2343, 2396, 2459, 2479, 2517, 2539, 2569, 2665, 2713, 2774, 2860, 2977, 3032, 3072, 3164, 3207, 3290, 3368, 3443, 3496, 3537, 3629, 3669, 3712, 3798, 3892, 4133, 4211, 4319, 4370], 'Scholar,': [606, 1162, 1265, 1682, 1716, 1772, 1808, 1888, 2116, 2149, 2186, 2266, 2307, 2397, 2460, 2480, 2518, 2540], '2.Collins': [607], 'F.S.': [608, 1137, 1530], 'Brooks': [609, 1118, 1531], 'L.D.': [610, 907, 1119, 1532, 2430], 'Chakravarti': [611, 916, 1533], 'A': [613, 1144, 1535, 4425], 'DNA': [614, 1286, 1502, 1536, 2249, 3352, 3390], 'polymorphism': [615, 1537, 3053], 'discovery': [616, 1538, 2442], 'resource': [617, 1539, 1748, 1849, 1959, 2693, 4042], 'research': [619, 1541, 2696], 'on': [620, 1542, 1638, 2169, 2200, 2697, 4100, 4179, 4225, 4322], 'variation.Genome': [623, 1545], 'Res.': [624, 1546, 1708, 1764, 1800, 1914, 1975, 2012, 2143, 2178, 2204, 2336, 2389, 2658, 2970, 3025, 3436, 3530, 3622, 3662, 3791, 3885, 4126, 4204, 4363], '1998;': [625, 1547], '8:': [626, 1548, 2703], '1229-1231Crossref': [627, 1549], '(645)': [630, 1552], 'Scholar).': [632, 1515, 1554, 1622, 1838, 1922, 2212, 2344, 2570, 2666, 2861, 2978, 3033, 3165, 3291, 3497, 3630, 3670, 3893, 4320], 'Recent': [633], 'progress': [634], 'International': [637], 'Project': [639], '(3.Frazer': [643], 'K.A.': [644, 1279, 1495], 'Ballinger': [645, 1276, 1492], 'D.G.': [646, 1277, 1493], 'Cox': [647, 1280, 1496], 'D.R.': [648, 870, 991, 1281, 1497, 3646, 4188], 'Hinds': [649], 'D.A.': [650, 666, 1045, 1267, 1483], 'Stuve': [651, 1268, 1484], 'L.L.': [652, 1065, 1269, 1485], 'Gibbs': [653, 1032], 'R.A.': [654, 1033], 'Belmont': [655, 1034], 'J.W.': [656, 1035], 'Boudreau': [657], 'Hardenbol': [659], 'Leal': [661], 'S.M.': [662], 'Pasternak': [663], 'S.': [664, 686, 722, 802, 860, 883, 891, 925, 947, 953, 1166, 1186, 1323, 1343, 1602, 1655, 1776, 1812, 1861, 1988, 2026, 2124, 2192, 2240, 2522, 3172, 3255, 3343], 'Wheeler': [665, 1044], 'Willis': [667], 'T.D.': [668, 1174, 1331], 'Yu': [669, 695, 2271, 3461], 'F.': [670, 792, 1212, 1222, 1369, 1379, 1659, 1690, 1694, 1865, 1896, 1900, 2372, 2412, 2641, 2947, 3002], 'Yang': [671, 1221, 1378, 2279, 3469], 'H.': [672, 678, 688, 702, 704, 726, 760, 774, 981, 985, 1091, 1105, 1109, 1176, 1240, 1333, 1397, 1730, 1941, 2188, 2242, 2675, 3345], 'Zeng': [673, 982, 2686], 'C.': [674, 682, 804, 949, 955, 983, 1005, 1220, 1236, 1242, 1377, 1393, 1399, 2376, 2408, 2488, 2645, 2683, 2747, 2831, 3047, 3180, 3263, 3683], 'Gao': [675, 2485, 2828, 3680], 'Y.': [676, 742, 750, 754, 756, 762, 764, 832, 842, 931, 989, 2482, 2689, 2825, 3677], 'Hu': [677, 679], 'W.': [680, 684, 694, 746, 758, 826, 929, 1182, 1339, 4347], 'Li': [681, 930, 1110, 2671, 2680, 2688, 3036], 'Lin': [683, 924, 2273, 3463], 'Liu': [685, 753], 'Pan': [687], 'Tang': [689], 'X.': [690, 748, 766, 1234, 1391, 2486, 2492, 2677, 2829, 2835, 3040, 3681, 3687], 'Wang': [691, 693, 759, 761, 763, 1104, 1112, 1114, 1124, 2682], 'Zhang': [697, 699, 980, 1223, 1227, 1380, 1384, 4342, 4344], 'B.': [698, 712, 1732, 1943, 2542, 2739], 'Q.': [700, 1111, 2681], 'Zhao': [701, 703, 984], 'Zhou': [705], 'Gabriel': [707, 1048], 'S.B.': [708, 1049], 'Barry': [709], 'Blumenstiel': [711], 'Camargo': [713], 'Defelice': [715], 'Faggart': [717], 'Goyette': [719], 'Gupta': [721], 'Moore': [723], 'Nguyen': [725, 2421], 'Onofrio': [727, 1050], 'R.C.': [728, 1051], 'Parkin': [729], 'Roy': [731], 'Stahl': [733], 'E.': [734, 736, 993, 1041, 1273, 1275, 1489, 1491, 2951, 3006, 3176, 3259], 'Winchester': [735], 'Shen': [741, 755, 1211, 1368], 'Yao': [743, 2491, 2834, 3686], 'Z.': [744, 1089, 1113, 4345], 'Huang': [745, 1193, 1350, 2289, 3479], 'Chu': [747], 'He': [749], 'Jin': [751, 2425, 2487, 2830, 3682], 'Sun': [757], 'Xiong': [765], 'Xu': [767], 'Waye': [769], 'M.M.': [770], 'Tsui': [771, 823], 'S.K.': [772, 1085, 3146], 'Xue': [773], 'Wong': [775], 'J.T.': [776], 'Galver': [777], 'L.M.': [778, 1133], 'Fan': [779], 'J.B.': [780], 'Gunderson': [781], 'Murray': [783], 'S.S.': [784], 'Oliphant': [785], 'A.R.': [786, 1180, 1337], 'Chee': [787], 'M.S.': [788, 800, 1123], 'Montpetit': [789], 'Chagnon': [791], 'Ferretti': [793], 'V.': [794, 1740, 1951, 2157, 2422, 2941, 2996], 'Leboeuf': [795], 'Olivier': [797], 'J.F.': [798], 'Phillips': [799, 1595], 'Roumy': [801], 'Sallée': [803], 'Verner': [805], 'Hudson': [807], 'T.J.': [808, 2380, 2649], 'Kwok': [809], 'P.Y.': [810], 'Cai': [811], 'Koboldt': [813], 'D.C.': [814], 'Miller': [815, 4346], 'R.D.': [816], 'Pawlikowska': [817], 'Taillon-Miller': [819], 'Xiao': [821], 'L.C.': [824], 'Mak': [825], 'Song': [827, 2310, 3504, 3765, 3859], 'Y.Q.': [828], 'Tam': [829], 'P.K.': [830], 'Nakamura': [831], 'Kawaguchi': [833], 'T.': [834, 836, 838, 846, 848, 971, 1001, 1226, 1383, 2190, 2440, 2544, 2753, 3644, 4186], 'Kitamoto': [835], 'Morizono': [837], 'Nagashima': [839], 'Ohnishi': [841], 'Sekine': [843], 'Tanaka': [845], 'Tsunoda': [847, 970], 'Deloukas': [849], 'Bird': [851], 'C.P.': [852], 'Delgado': [853], 'Dermitzakis': [855], 'E.T.': [856], 'Gwilliam': [857], 'Hunt': [859], 'Morrison': [861], 'Powell': [863], 'Stranger': [865], 'B.E.': [866], 'Whittaker': [867], 'Bentley': [869], 'Daly': [871, 1058], 'M.J.': [872, 1059, 1214, 1371], 'de': [873], 'Bakker': [874], 'P.I.': [875], 'Barrett': [876], 'Chretien': [878], 'Y.R.': [879, 2284, 3474], 'Maller': [880], 'McCarroll': [882], 'Patterson': [884], "Pe'er": [886], 'I.': [887, 987, 999, 1047], 'Price': [888], 'Purcell': [890], 'Richter': [892, 1052], 'D.J.': [893, 921, 937, 1053, 4349], 'Sabeti': [894], 'Saxena': [896], 'Schaffner': [898], 'S.F.': [899, 4337], 'Sham': [900], 'P.C.': [901], 'Varilly': [902], 'Stein': [906], 'Krishnan': [908], 'Smith': [910], 'A.V.': [911], 'Tello-Ruiz': [912], 'M.K.': [913], 'Thorisson': [914], 'G.A.': [915, 2943, 2998], 'Chen': [918, 1088, 1181, 1338, 1777, 1989], 'P.E.': [919], 'Cutler': [920], 'Kashuk': [922], 'C.S.': [923, 2737], 'Abecasis': [926], 'G.R.': [927], 'Guan': [928], 'Munro': [932], 'H.M.': [933], 'Qin': [934], 'Z.S.': [935], 'Thomas': [936, 1599], 'McVean': [938], 'G.': [939, 963, 1101, 2679], 'Auton': [940], 'Bottolo': [942], 'Cardin': [944], 'Eyheramendy': [946], 'Freeman': [948, 1187, 1344], 'Marchini': [950], 'Myers': [952], 'Spencer': [954], 'Stephens': [956], 'Donnelly': [958], 'Cardon': [960], 'L.R.': [961], 'Clarke': [962], 'Evans': [964], 'D.M.': [965], 'Morris': [966], 'A.P.': [967], 'Weir': [968], 'B.S.': [969], 'Mullikin': [972], 'J.C.': [973, 1097], 'Sherry': [974], 'S.T.': [975, 3415, 3601, 4105], 'Feolo': [976], 'Skol': [978], 'Matsuda': [986], 'Fukushima': [988], 'Macer': [990], 'Suda': [992], 'Rotimi': [994], 'C.N.': [995], 'Adebamowo': [996], 'C.A.': [997], 'Ajayi': [998], 'Aniagwu': [1000], 'Marshall': [1002, 1201, 1358], 'P.A.': [1003], 'Nkwodimmah': [1004], 'Royal': [1006], 'C.D.': [1007], 'Leppert': [1008], 'M.F.': [1009], 'Dixon': [1010], 'Peiffer': [1012], 'Qiu': [1014], 'Kent': [1016], 'Kato': [1018], 'Niikawa': [1020], 'Adewole': [1022], 'I.F.': [1023], 'Knoppers': [1024], 'B.M.': [1025], 'Foster': [1026], 'M.W.': [1027], 'Clayton': [1028], 'E.W.': [1029], 'Watkin': [1030], 'Muzny': [1036], 'Nazareth': [1038], 'Sodergren': [1040], 'Weinstock': [1042], 'G.M.': [1043, 2309, 3503, 3764, 3858], 'Yakub': [1046], 'Birren': [1056], 'B.W.': [1057], 'Wilson': [1062], 'R.K.': [1063], 'Fulton': [1064], 'Rogers': [1066], 'Burton': [1068], 'Carter': [1070, 1237, 1394], 'N.P.': [1071, 1238, 1395], 'Clee': [1072], 'C.M.': [1073, 2153, 2374, 2643], 'Griffiths': [1074], 'Jones': [1076, 1243, 1400], 'M.C.': [1077], 'McLay': [1078], 'Plumb': [1080], 'R.W.': [1081], 'Ross': [1082], 'M.T.': [1083], 'Sims': [1084], 'Willey': [1086], 'D.L.': [1087, 3182, 3265], 'Han': [1090], 'Kang': [1092], 'Godbout': [1094], 'Wallenburg': [1096], "L'Archevêque": [1098], 'Bellemare': [1100], 'Saeki': [1102], 'An': [1106, 1819, 2033, 2062], 'Fu': [1108], 'Holden': [1116], 'A.L.': [1117], 'McEwen': [1120], 'J.E.': [1121], 'Guyer': [1122], 'V.O.': [1125], 'Peterson': [1126], 'J.L.': [1127, 1188, 1345], 'Shi': [1128], 'Spiegel': [1130], 'Sung': [1132], 'Zacharia': [1134], 'L.F.': [1135], 'Collins': [1136], 'Kennedy': [1138], 'Jamieson': [1140], 'Stewart': [1142], 'second': [1145], 'generation': [1146, 4356], 'haplotype': [1148], 'map': [1149], 'over': [1151], '3.1': [1152], 'million': [1153], 'SNPs.Nature.': [1154], '2007;': [1155, 1801, 2013, 2179, 2448, 3158, 3663, 4205], '449:': [1156], '851-861Crossref': [1157], '(3605)': [1160], '4.Redon': [1163], 'Ishikawa': [1165, 1322], 'Fitch': [1167, 1324], 'K.R.': [1168, 1325], 'Feuk': [1169, 1326], 'Perry': [1171, 1328], 'G.H.': [1172, 1329], 'Andrews': [1173, 1330], 'Fiegler': [1175, 1332], 'Shapero': [1177, 1334], 'M.H.': [1178, 1335, 3417, 3603, 4107], 'Carson': [1179, 1336], 'Cho': [1183, 1340], 'E.K.': [1184, 1341], 'Dallaire': [1185, 1342], 'González': [1189, 1346], 'J.R.': [1190, 1200, 1347, 1357, 2432], 'Gratacòs': [1191, 1348], 'Kalaitzopoulos': [1195, 1352], 'Komura': [1197, 1354], 'MacDonald': [1199, 1356], 'Mei': [1203, 1360], 'Montgomery': [1205, 1362], 'Nishimura': [1207, 1364], 'Okamura': [1209, 1366], 'Somerville': [1213, 1370], 'Tchinda': [1215, 1372], 'Valsesia': [1217, 1374], 'Woodwark': [1219, 1376], 'Zerjal': [1225, 1382], 'Armengol': [1229, 1386], 'Conrad': [1231, 1388], 'D.F.': [1232, 1389], 'Estivill': [1233, 1390], 'Tyler-Smith': [1235, 1392], 'Aburatani': [1239, 1396], 'Lee': [1241, 1398, 2275, 3145, 3465], 'K.W.': [1244, 1401, 2313, 3507, 3768, 3862], 'Scherer': [1245, 1402], 'S.W.': [1246, 1403], 'Hurles': [1247, 1404], 'M.E.': [1248, 1405, 3049], 'Global': [1249, 1406], 'copy': [1252, 1317, 1409], 'number': [1253, 1318, 1410, 2611, 2911, 2920], 'genome.Nature.': [1257, 1414], '2006;': [1258, 1415, 1675, 1765, 1881, 1976, 2109, 2533], '444:': [1259, 1416], '444-454Crossref': [1260, 1417], '(3330)': [1263, 1420], '5.Hinds': [1266], 'Nilsen': [1270, 1486], 'G.B.': [1271, 1487], 'Halperin': [1272, 1488], 'Eskin': [1274, 1490], 'Frazer': [1278, 1494], 'Whole-genome': [1282, 1498], 'patterns': [1283, 1499, 2585], 'common': [1285, 1501], 'three': [1289, 1505, 3751], 'populations.Science.': [1291, 1507], '2005;': [1292, 1508, 1709, 1915, 2259, 2563, 2971, 3026, 3061, 3362], '307:': [1293, 1509], '1072-1079Crossref': [1294, 1510], '(976)': [1297, 1513], 'Scholar)': [1299, 1422, 2714, 2775, 3073, 3208, 3369, 3444, 3538, 3713, 4134, 4212, 4371], 'has': [1300, 3234], 'provided': [1301], 'wealth': [1303], 'information': [1305], 'detailing': [1306], 'tens': [1307], 'millions': [1309], 'between': [1314, 4235], 'individuals,': [1315], 'including': [1316, 1926, 3800, 4402], '(4.Redon': [1320], 'Scholar,5.Hinds': [1482], 'estimated': [1518], '∼90%': [1520], 'caused': [1526], 'by': [1527, 2225, 2255, 3093, 3120, 3153, 3358, 3455, 3928], 'SNPs': [1528, 1567, 1792, 2004, 4144], '(2.Collins': [1529], 'For': [1555, 1839, 2806, 2905, 3223], 'example,': [1556, 1840, 2807, 2906, 3224], 'amino': [1559, 2072, 2237, 3565, 3804, 3899, 4255, 4420], 'acids': [1560, 2238, 4421], 'proteins,': [1562], '(nsSNPs)': [1568], 'gene': [1571, 3228], 'regions,': [1573], 'account': [1575], 'nearly': [1577], 'half': [1578], 'known': [1581, 2139, 3449], 'linked': [1584], 'inherited': [1587], '(6.Stenson': [1589], 'P.D.': [1590], 'Ball': [1591], 'E.V.': [1592], 'Mort': [1593], 'A.D.': [1596], 'Shiel': [1597], 'J.A.': [1598], 'N.S.': [1600], 'Abeysinghe': [1601], 'Krawczak': [1603], 'Cooper': [1605], 'D.N.': [1606], 'Human': [1607], 'Gene': [1608], 'Mutation': [1609], 'Database': [1610], '(HGMD):': [1611], '2003': [1612], 'update.Hum.': [1613], 'Mutat.': [1614], '2003;': [1615], '21:': [1616], '577-581Crossref': [1617], '(1361)': [1620], 'regard,': [1625, 3294, 3980], 'numerous': [1626], 'efforts': [1627], 'been': [1629], 'elucidate': [1632], 'how': [1633, 3311, 3323], 'generate': [1635], 'deleterious': [1636, 2104], 'effects': [1637, 1670, 1701, 1854, 1876, 1907], 'function': [1642], 'proteins': [1644, 2222, 2251, 2356, 2630, 3354, 3722, 4375], 'their': [1646, 2332, 3526, 3787, 3881, 4217, 4377], 'cancers': [1649, 2992], '(7.Reumers': [1652, 1858], 'Maurer-Stroh': [1654, 1860], 'Schymkowitz': [1656, 1685, 1862, 1891], 'Rousseau': [1658, 1693, 1864, 1899], 'SNPeffect': [1660, 1842, 1866], 'v2.0:': [1661, 1867], 'new': [1663, 1869, 2900, 3242, 3816, 4355], 'step': [1664, 1870], 'investigating': [1666, 1872], 'molecular': [1668, 1699, 1852, 1874, 1905], 'phenotypic': [1669, 1700, 1853, 1875, 1906, 3336], 'SNPs.Bioinformatics.': [1674, 1880], '2183-2185Crossref': [1677, 1883], '(77)': [1680, 1886], '8.Reumers': [1683, 1889], 'Ferkinghoff-Borg': [1687, 1893], 'Stricher': [1689, 1895], 'Serrano': [1691, 1897], 'SNPeffect:': [1695, 1901], 'mapping': [1698, 1904, 2165, 2198, 4233, 4324], 'SNPs.Nucleic': [1706, 1912], 'Acids': [1707, 1763, 1799, 1913, 1974, 2011, 2142, 2177, 2203, 2335, 2388, 2657, 2969, 3024, 3435, 3529, 3621, 3661, 3790, 3884, 4125, 4203, 4362], '33:': [1710, 1916, 2972, 3027], 'D527-D532Crossref': [1711, 1917], '(130)': [1714, 1920], '9.Packer': [1717], 'B.R.': [1718, 1929], 'Yeager': [1719, 1930], 'Burdett': [1721, 1932], 'Welch': [1723, 1934], 'Beerman': [1725, 1936], 'Qi': [1727, 1938], 'Sicotte': [1729, 1940], 'Staats': [1731, 1942], 'Acharya': [1733, 1944], 'Crenshaw': [1735, 1946], 'Eckert': [1737, 1948], 'Puri': [1739, 1950], 'Gerhard': [1741, 1952], 'D.S.': [1742, 1953], 'Chanock': [1743, 1954], 'S.J.': [1744, 1955], 'SNP500Cancer:': [1745, 1956], 'public': [1747, 1958], 'validation,': [1751, 1962], 'assay': [1752, 1963], 'development,': [1753, 1964], 'frequency': [1755, 1966], 'candidate': [1761, 1972], 'genes.Nucleic': [1762, 1973], '34:': [1766, 1977], 'D617-D621Crossref': [1767, 1978], '(247)': [1770, 1981], '10.Jegga': [1773], 'A.G.': [1774, 1986], 'Gowrisankar': [1775, 1987], 'Aronow': [1779, 1991], 'B.J.': [1780, 1992], 'PolyDoms:': [1781, 1993], 'whole': [1783, 1995], 'genome': [1784, 1996], 'identification': [1788, 2000], 'with': [1793, 2005, 2093, 2136, 2172, 2615, 2631, 2781, 3806, 4376], 'impact': [1797, 2009], 'disease.Nucleic': [1798, 2010], '35:': [1802, 2014, 2180, 3664, 4206], 'D700-D706Crossref': [1803, 2015], '(49)': [1806, 2018], '11.Yang': [1809], 'J.O.': [1810, 2024], 'Hwang': [1811, 2025], 'Oh': [1813, 2027, 2314, 3508, 3769, 3863], 'Bhak': [1815, 2029], 'Sohn': [1817, 2031], 'T.K.': [1818, 2032], 'database-pipeline': [1821, 2035], 'system': [1822, 2036], 'studying': [1824, 2038], 'diseases.BMC': [1829, 2043], 'Bioinformatics.': [1830, 2044], '2008;': [1831, 2045, 2205, 2300, 2390, 2506, 2659, 2849, 3201, 3284, 3490, 3701], '9:': [1832, 2046], 'S19Crossref': [1833, 2047], '(29)': [1836, 2050], 'comprehensive': [1848, 2293, 3295, 3483], 'Later,': [1923, 3396], 'several': [1924, 2788], 'databases,': [1925], 'SNP500Cancer': [1927], '(9.Packer': [1928], 'Scholar),': [1983, 2020, 2052, 3799], 'PolyDoms': [1984], '(10.Jegga': [1985], 'Diseasome': [2022], '(11.Yang': [2023], 'constructed': [2054, 2810], 'dissecting': [2056], 'cancer-': [2058], 'disease-related': [2060], 'nsSNPs.': [2061], 'nsSNP': [2063, 2915, 2980, 3078, 3111, 3237, 3724, 3735, 4241], 'change': [2065, 2328, 3522, 3783, 3801, 3877, 3911], 'physicochemical': [2067], 'property': [2068], 'wild-type': [2071], 'acid': [2073, 3566, 3805, 3900, 4256], 'dynamics,': [2080], 'disrupts': [2081, 2930], 'interacting': [2083], 'interface,': [2084], 'prohibits': [2086], 'form': [2090], 'complex': [2092], 'its': [2094, 2931, 3089, 3955, 4263], 'partners': [2095], '(12.Yue': [2096], 'Moult': [2098], 'Identification': [2100], 'SNPs.J.': [2106], 'Mol.': [2107, 2471], 'Biol.': [2108, 2472, 3059], '356:': [2110], '1263-1274Crossref': [2111], '(212)': [2114], '13.Stitziel': [2117], 'N.O.': [2118], 'Binkowski': [2119], 'T.A.': [2120], 'Tseng': [2121, 2285, 3475], 'Y.Y.': [2122], 'Kasif': [2123], 'Liang': [2125], 'topoSNP:': [2127], 'topographic': [2129], 'without': [2138], 'disease': [2140, 4045], 'association.Nucleic': [2141], '2004;': [2144], '32:': [2145], 'D520-D522Crossref': [2146], '14.Uzun': [2150], 'Leslin': [2152], 'Abyzov': [2154], 'Ilyin': [2156], 'Structure': [2158], '(StSNP):': [2160], 'web': [2162], 'server': [2163, 2197], 'modeling': [2167], 'structures': [2171], 'linkage': [2173], 'metabolic': [2175], 'pathways.Nucleic': [2176], 'W384-W392Crossref': [2181], '(44)': [2184], '15.Kono': [2187], 'Yuasa': [2189], 'Nishiue': [2191], 'Yura': [2193], 'coliSNP': [2195], 'structures.Nucleic': [2202], '36:': [2206, 2391, 2660], 'D409-D413Crossref': [2207], '(19)': [2210], 'Alternatively,': [2213], 'post-translational': [2218, 2698], 'modifications': [2219], '(PTMs)': [2220], '(e.g.': [2223], 'phosphorylation)': [2224], 'changing': [2226, 4247], 'residue': [2228, 3091, 3808], 'target': [2232, 3921], 'key': [2235], 'flanking': [2236], '(16.Savas': [2239, 3342], 'Ozcelik': [2241, 3341, 3344], 'Phosphorylation': [2243, 3346], 'states': [2244, 3347], 'cell': [2246, 2936, 2958, 3013, 3349, 3393], 'cycle': [2247, 2937, 2959, 3014, 3350], 'repair': [2250, 3353], 'can': [2252, 3355], 'be': [2253, 3304, 3356, 3453, 3925, 4393], 'altered': [2254, 3357], 'nsSNPs.BMC': [2257, 3360], 'Cancer.': [2258, 3361], '5:': [2260, 3363], '107Crossref': [2261, 3364], '(24)': [2264, 3163, 3367], '17.Yang': [2267], 'C.Y.': [2268, 2290, 3458, 3480], 'Chang': [2269, 3459], 'C.H.': [2270, 3460], 'Y.L.': [2272, 3462], 'T.C.': [2274, 3464], 'S.A.': [2276, 3466], 'Yen': [2277, 3467], 'C.C.': [2278, 3468], 'J.M.': [2280, 2282, 3470, 3472], 'Lai': [2281, 3471], 'Hong': [2283, 3473], 'T.L.': [2286, 3476, 4339], 'Chao': [2287, 3477], 'K.M.': [2288, 3478], 'PhosphoPOINT:': [2291, 3481], 'interactome': [2296, 3486], 'phospho-protein': [2298, 3488], 'database.Bioinformatics.': [2299, 3489], '24:': [2301, 3491], 'i14-20Crossref': [2302, 3492], '(73)': [2305, 3495], '18.Ryu': [2308], 'Kim': [2312, 2318, 3506, 3512, 3767, 3773, 3861, 3867], 'K.S.': [2315, 3509, 3770, 3864], 'Park': [2316, 2427, 3141, 3510, 3771, 3865], 'K.J.': [2317, 3511, 3772, 3866], 'J.H.': [2319, 3513, 3774, 3868], 'Genome-wide': [2320, 3514, 3775, 3869], 'predict': [2323, 2498, 2802, 2818, 2841, 3517, 3693, 3715, 3778, 3872], 'corresponding': [2333, 3527, 3788, 3882, 4218], 'kinases.Nucleic': [2334, 3528, 3789, 3883], '2009;': [2337, 2473, 2702, 2768, 3531, 3792, 3886], '37:': [2338, 3532, 3793, 3887], '1297-1307Crossref': [2339, 3533, 3794, 3888], '(43)': [2342, 3536, 3797, 3891], 'eukaryotes,': [2346], 'one': [2349], 'most': [2352, 2362, 3984], 'PTMs': [2354], 'plays': [2358], 'essential': [2359], 'pathways': [2364, 3319], 'regulates': [2366], 'cellular': [2367], 'dynamics': [2368], 'plasticity': [2370], '(19.Diella': [2371, 2640], 'Gould': [2373, 2642], 'Chica': [2375, 2644], 'Via': [2377, 2646], 'Gibson': [2379, 2648], 'Phospho.ELM:': [2381, 2650], 'sites—update': [2386, 2655], '2008.Nucleic': [2387, 2656], 'D240-D244Crossref': [2392, 2661], '(209)': [2395, 2664], '20.Linding': [2398], 'Jensen': [2400], 'L.J.': [2401], 'Ostheimer': [2402], 'G.J.': [2403], 'van': [2404], 'Vugt': [2405], 'M.A.': [2406], 'Jørgensen': [2407, 2746], 'Miron': [2409], 'I.M.': [2410], 'Diella': [2411], 'Colwill': [2413], 'Taylor': [2415], 'Elder': [2417], 'Metalnikov': [2419], 'Pasculescu': [2423, 2740], 'J.G.': [2428], 'Samson': [2429], 'Woodgett': [2431], 'Russell': [2433], 'R.B.': [2434], 'Bork': [2435], 'Yaffe': [2437], 'M.B.': [2438], 'Pawson': [2439, 2752], 'Systematic': [2441], 'vivo': [2445], 'networks.Cell.': [2447], '129:': [2449], '1415-1426Abstract': [2450], 'Full': [2451, 2453, 2509, 2511, 2705, 2707, 2852, 2854, 3064, 3066, 3704, 3706], 'Text': [2452, 2454, 2510, 2512, 2706, 2708, 2853, 2855, 3065, 3067, 3705, 3707], 'PDF': [2455, 2513, 2709, 2856, 3068, 3708], '(612)': [2458], '21.Miller': [2461], 'M.L.': [2462], 'Blom': [2463], 'Kinase-specific': [2465], 'prediction': [2466, 2558, 3375], 'sites.Methods': [2470], '527:': [2474], '299-310Crossref': [2475], '(55)': [2478], '22.Xue': [2481], 'Ren': [2483, 2826, 3678], 'Wen': [2489, 2832, 3684], 'GPS': [2493, 2836, 3673, 3688], '2.0,': [2494, 2837, 3689], 'tool': [2496, 2839, 3691], 'hierarchy.Mol.': [2503, 2846, 3698], 'Cell.': [2504, 2700, 2847, 3699], 'Proteomics.': [2505, 2701, 2848, 3700], '7:': [2507, 2850, 3702], '1598-1608Abstract': [2508, 2851, 3703], '(534)': [2516, 2859, 3711], '23.Hjerrild': [2519], 'Gammeltoft': [2521], 'Phosphoproteomics': [2523], 'toolbox:': [2524], 'computational': [2525, 2557, 2797, 2866], 'biology,': [2526], 'chemistry': [2528], 'mass': [2530], 'spectrometry.FEBS': [2531], 'Lett.': [2532], '580:': [2534], '4764-4770Crossref': [2535], '(54)': [2538], '24.Kobe': [2541], 'Kampmann': [2543], 'Forwood': [2545], 'J.K.': [2546], 'Listwan': [2547], 'Brinkworth': [2549], 'R.I.': [2550], 'Substrate': [2551], 'specificity': [2552], 'kinases': [2555, 2576], 'substrates.Biochim.': [2560], 'Biophys.': [2561], 'Acta.': [2562], '1754:': [2564], '200-209Crossref': [2565], '(88)': [2568], 'Generally': [2571], 'vivo,': [2573], '(PKs)': [2577], 'recognize': [2579], 'distinct': [2580], 'short': [2581], 'peptide': [2582], 'motifs': [2583], 'attach': [2587], 'phosphate': [2588], 'moieties': [2589], 'Ser,': [2591, 2633, 3903], 'Thr,': [2592, 2635, 3904], 'Tyr': [2594, 2638, 3906], 'residues.': [2595], 'Conventional': [2596], 'experimental': [2597, 2792, 2883], 'identifications': [2598], 'recent': [2600], 'advances': [2601], 'high': [2603], 'throughput': [2604], 'MS': [2605], 'techniques': [2606], 'generated': [2608], 'phosphorylated': [2613, 2629, 3926], 'substrates': [2614, 2723], 'confirmed': [2616], 'sites.': [2618, 2805, 3725], 'From': [2619], 'primary': [2620], 'scientific': [2621, 2726], 'literature,': [2622], 'Phospho.ELM': [2623], '8.1': [2624], 'collected': [2625, 2715, 2873, 3592], '>4,600': [2626], 'experimentally': [2627, 2717, 3404], 'verified': [2628, 2718, 3405], '14,518': [2632], '2,914': [2634], '2,217': [2637], 'With': [2667], 'strategy,': [2670], 'et': [2672, 2734, 3037, 3169, 3398, 3500], 'al.': [2673, 2735, 3038, 3170, 3399, 3501], '(25.Li': [2674], 'Xing': [2676], 'Ding': [2678], 'Xie': [2684], 'SysPTM:': [2690], 'systematic': [2692], 'proteomic': [2695], 'modifications.Mol.': [2699], '1839-1849Abstract': [2704], '(111)': [2712], '87,068': [2716], '24,705': [2722], 'literature': [2727], 'MS-derived': [2729], 'experiments.': [2730], 'recently,': [2732, 3167], 'Tan': [2733], '(26.Tan': [2736], 'Bodenmiller': [2738], 'Jovanovic': [2742], 'Hengartner': [2744], 'M.O.': [2745], 'Bader': [2748], 'G.D.': [2749], 'Aebersold': [2750], 'Linding': [2754], 'Comparative': [2756], 'reveals': [2758], 'conserved': [2759], 'networks': [2762], 'implicated': [2763], 'multiple': [2765], 'diseases.Sci.': [2766], 'Signal.': [2767], '2:': [2769], 'ra39Crossref': [2770], '(160)': [2773], 'compiled': [2776], 'data': [2779, 4059, 4095, 4379, 4411], 'set': [2780], '23,979': [2782], 'non-redundant': [2783, 3653, 4195], 'databases.': [2790], 'Besides': [2791], 'methods,': [2793], 'variety': [2795, 2990], 'approaches': [2798], 'previously': [2809, 3762], 'highly': [2812], 'software': [2814, 3675], '2.0)': [2816], 'hierarchy': [2823], '(22.Xue': [2824, 3676], 'latest': [2863], 'compendium': [2864], 'resources': [2867], 'manually': [2872], 'upon': [2877], 'request.': [2878], 'Recently,': [2879, 3498], 'more': [2880, 2882], 'observations': [2884], 'suggested': [2886], 'indirectly': [2890], 'directly': [2892], 'disrupt': [2893], 'original': [2895, 3823], 'create': [2899, 3382, 3813, 3831], '(supplemental': [2902], 'Table': [2903], 'S1).': [2904], 'OGG1': [2908, 2928], '(RefSeq': [2909], 'accession': [2910, 2919], 'NM_002542)': [2912], 'harbors': [2913], 'S326C': [2917], '(dbSNP': [2918, 4096], 'rs1052133),': [2921], 'status': [2926, 3217], 'nucleolar': [2932], 'localization': [2933], 'during': [2934, 2956, 3011], '(27.Luna': [2938, 2993], 'Rolseth': [2940, 2995], 'Hildrestrand': [2942, 2997], 'Otterlei': [2944, 2999], 'Dantzer': [2946, 3001], 'Bjørås': [2948, 3003], 'Seeberg': [2950, 3005], 'Dynamic': [2952, 3007], 'relocalization': [2953, 3008], 'hOGG1': [2955, 3010], 'disrupted': [2961, 3016], 'cells': [2963, 3018], 'harbouring': [2964, 3019], 'hOGG1-Cys326': [2966, 3021], 'polymorphic': [2967, 3022], 'variant.Nucleic': [2968, 3023], '1813-1824Crossref': [2973, 3028], '(82)': [2976, 3031], 'This': [2979], 'further': [2982, 3307], 'risk': [2986], 'allele': [2987, 4388], '2005,': [3035], '(28.Li': [3039], 'Dumont': [3041], 'Della': [3043], 'Pietra': [3044], 'Shetler': [3046], 'Murphy': [3048], 'codon': [3051], '47': [3052], 'p53': [3055, 3081, 3101], 'functionally': [3057], 'significant.J.': [3058], 'Chem.': [3060], '280:': [3062], '24245-24251Abstract': [3063], '(95)': [3071], 'observed': [3074, 3446, 3896, 4001], 'P47S': [3077], '(rs1800371)': [3079], '(NM_000546)': [3082], 'strongly': [3083], 'compromises': [3084], 'level': [3087], 'Ser-46': [3092], 'p38': [3094], 'MAPK': [3095], 'reduces': [3097], 'ability': [3099], 'apoptosis': [3104, 3128], 'up': [3105], '5-fold.': [3107], 'Moreover,': [3108, 3936], 'D149G': [3110], '(rs1801724)': [3112], 'p21WAF1/CIP1': [3114, 3152], '(NM_078467)': [3115], 'attenuate': [3117], 'Ser-146': [3118], 'PKCδ': [3121], 'resist': [3123], 'tumor': [3124], 'necrosis': [3125], 'factor': [3126], 'α-induced': [3127], 'role': [3133], 'cancer': [3135], 'development': [3136], '(29.Oh': [3137], 'Y.T.': [3138], 'Chun': [3139], 'K.H.': [3140], 'B.D.': [3142], 'Choi': [3143], 'J.S.': [3144], 'Regulation': [3147], 'cyclin-dependent': [3149], 'inhibitor': [3151], 'Cdelta-mediated': [3156], 'phosphorylation.Apoptosis.': [3157], '12:': [3159], '1339-1347Crossref': [3160], 'Gentile': [3168], '(30.Gentile': [3171, 3254], 'Martin': [3173, 3256], 'Scappini': [3175, 3258], 'Williams': [3177, 3260], 'Erxleben': [3179, 3262], 'Armstrong': [3181, 3264], 'ERG1': [3185, 3268], 'channel': [3186, 3195, 3221, 3232, 3269, 3278], 'polymorphism,': [3187, 3270], 'K897T,': [3188, 3271], 'creates': [3189, 3240, 3272], 'inhibits': [3194, 3277], 'activity.Proc.': [3196, 3279], 'Natl.': [3197, 3280], 'Acad.': [3198, 3281], 'Sci.': [3199, 3282], 'U.S.A.': [3200, 3283], '105:': [3202, 3285], '14704-14708Crossref': [3203, 3286], '(36)': [3206, 3289], 'predicted': [3209], '16': [3210], 'ion': [3220], 'ether-a-gogo-related': [3227], '1,': [3229], 'ERG1/KCNH2/Kv11.1': [3230], '(NM_000238)': [3231], 'protein,': [3233], 'K897T': [3236], '(rs1805123),': [3238], 'AKT': [3243], 'prolong': [3247], 'QT': [3249], 'interval': [3250], 'cardiac': [3252], 'myocytes': [3253], 'studies': [3296], 'alter': [3300], 'will': [3303], 'helpful': [3305], 'involved': [3315], 'regulating': [3317], 'processes': [3321], 'determine': [3331], 'population': [3333], 'diversity': [3334], 'plasticity.': [3337], 'Previously,': [3338], 'Savas': [3339], 'small': [3373], 'scale': [3374, 3556], 'identify': [3377], '15': [3378], 'remove': [3384, 3821, 3836, 3954], '14': [3389], 'repair-': [3391], 'cycle-related': [3394], 'Yang,': [3397], 'mapped': [3400], '109,262': [3401], 'taken': [3408, 3636], 'NCBI': [3411, 3430, 3596, 3616, 3647, 4120, 4137, 4177, 4189, 4333], 'dbSNP': [3412, 3597, 4236, 4378], '(31.Sherry': [3414, 3600, 4104], 'Ward': [3416, 3602, 4106], 'Kholodov': [3418, 3604, 4108], 'Baker': [3420, 3606, 4110], 'Phan': [3422, 3608, 4112], 'Smigielski': [3424, 3610, 4114], 'E.M.': [3425, 3611, 4115], 'Sirotkin': [3426, 3612, 4116], 'dbSNP:': [3428, 3614, 4118], 'variation.Nucleic': [3434, 3620, 4124], '2001;': [3437, 3623, 4127], '29:': [3438, 3624, 4128], '308-311Crossref': [3439, 3625, 4129], '(4881)': [3442, 3628, 4132], '64': [3448], 'removed': [3454], '(17.Yang': [3457], 'Ryu': [3499], '(18.Ryu': [3502, 3763, 3857], 'took': [3539], '33,651': [3540], '(∼26%': [3544], 'nsSNPs)': [3546], 'Swiss-Prot/UniProt': [3549], 'survey': [3557], 'phosphovariants,': [3560], 'performed': [3578], 'humans.': [3590], '91,797': [3593, 4403], 'Build': [3598, 3639, 4097, 4174], '130': [3599], 'mRNA/protein': [3633], 'sequences': [3634, 3649, 4191], 'RefSeq': [3638, 4173, 4374], '31': [3640, 4175], '(32.Pruitt': [3641, 4183], 'K.D.': [3642, 4184], 'Tatusova': [3643, 4185], 'Maglott': [3645, 4187], 'reference': [3648, 4190], '(RefSeq):': [3650, 4192], 'curated': [3652, 4194], 'genomes,': [3657, 4199], 'transcripts': [3658, 4200], 'proteins.Nucleic': [3660, 4202], 'D61-D65Crossref': [3665, 4207], '(2105)': [3668, 4210], 'used': [3672, 4327], '2.0': [3674], 'classified': [3743], 'five': [3747], 'groups.': [3748], 'first': [3750], '(I,': [3753], 'II,': [3754], 'III)': [3756, 3856], 'similarly': [3758], 'described': [3761], 'Ser/Thr/Tyr': [3807], 'vice': [3810], 'versa': [3811], '(Type': [3817, 3826, 3832, 3840, 3855, 3934], 'I': [3818, 3827], '(+))': [3819, 3834], '(−)),': [3828, 3842], 'II': [3833, 3841], 'mutations': [3844], 'PK': [3849, 3913, 4016], 'Also,': [3894], 'substitution': [3901, 4257], 'site;': [3918], 'still': [3924], 'but': [3927], 'type': [3931], 'IV).': [3935], 'Type': [3940, 4006], 'V': [3941], 'phosSNP': [3942, 4058], 'stop': [3950, 4423], 'codon,': [3951], 'following': [3956], 'C': [3962], 'terminus.': [3963], 'Unexpectedly,': [3964], '69.76%': [3968], '(64,035)': [3974], '17,614': [3976], 'Interestingly,': [3999], '74.58%': [4002], 'III': [4007], '(47,760),': [4009], 'suggesting': [4010], 'indirect': [4024], 'manner': [4025], 'our': [4037], 'represent': [4039], 'useful': [4041], 'future': [4044], 'diagnostics': [4046], 'basis': [4050], 'better': [4052], 'treatment.': [4055], 'he': [4063], 'supports': [4078], 'Windows,': [4079], 'Unix/Linux,': [4080], 'Mac': [4082], 'downloaded': [4091, 4170, 4221], '14,726,460': [4092], '130,': [4098], 'released': [4099], 'June': [4101], '18,': [4102], '2008)': [4103, 4182], 'FTP': [4138], 'server.': [4139], 'then': [4141, 4169], 'extracted': [4142], '368,140': [4143], '(cSNPs)': [4149], 'after': [4150], 'entries': [4153], 'characters': [4158], 'presented': [4160], 'lowercase': [4162], 'letters': [4163], '(SNPs': [4164], 'non-coding': [4166], 'sequences).': [4167], '(released': [4178, 4224], 'October': [4180], '28,': [4181], 'containing': [4213], '46,177': [4214], 'mRNAs': [4215], '“SNP_annotation_fix.txt”': [4223], 'September': [4226], '30,': [4227], '2008,': [4228], 'RefSeq),': [4229], 'contains': [4231], 'precalculated': [4232], 'RefSeq.': [4239], 'cSNP': [4246], 'subsequent': [4259], 'alteration': [4261], 'product': [4265], 'Based': [4321], 'file,': [4325], 'bl2seq': [4329], 'program': [4330], 'BLAST': [4334, 4351], 'package': [4335], '(33.Altschul': [4336], 'Madden': [4338], 'Schäffer': [4340], 'A.A.': [4341], 'Lipman': [4348], 'Gapped': [4350], 'PSI-BLAST:': [4353], 'search': [4360], 'programs.Nucleic': [4361], '1997;': [4364], '25:': [4365], '3389-3402Crossref': [4366], '(59933)': [4369], 'compare': [4373], 'pairwise': [4382], 'Then': [4384], 'positions': [4386], 'easily': [4394], 'found.': [4395], 'total,': [4397], '154,699': [4400], 'cSNPs,': [4401], '20,632': [4406], 'above': [4410], 'set,': [4412], 'there': [4413], '3,448': [4415], 'nonsense': [4416], 'changed': [4419], 'codons.': [4424], 'nonsen': [4429]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2107889651', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-09T10:43:07.572809', 'created_date': '2016-06-24'}