Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2106803404', 'doi': 'https://doi.org/10.1097/00062752-199811000-00007', 'title': 'Granulocyte colony-stimulating factor-mobilized granulocyte concentrate transfusions', 'display_name': 'Granulocyte colony-stimulating factor-mobilized granulocyte concentrate transfusions', 'publication_year': 1998, 'publication_date': '1998-11-01', 'ids': {'openalex': 'https://openalex.org/W2106803404', 'doi': 'https://doi.org/10.1097/00062752-199811000-00007', 'mag': '2106803404', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9814645'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00062752-199811000-00007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S15004046', 'display_name': 'Current Opinion in Hematology', 'issn_l': '1065-6251', 'issn': ['1065-6251', '1080-8213', '1531-7048'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113697653', 'display_name': 'Thomas H. Price', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Thomas H. Price', 'raw_affiliation_strings': ['Puget Sound Blood Center, University of Washington, Seattle, 98104, USA.'], 'affiliations': [{'raw_affiliation_string': 'Puget Sound Blood Center, University of Washington, Seattle, 98104, USA.', 'institution_ids': ['https://openalex.org/I201448701']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5113697653'], 'corresponding_institution_ids': ['https://openalex.org/I201448701'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.393, 'has_fulltext': False, 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.345374, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '5', 'issue': '6', 'first_page': '391', 'last_page': '395'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12172', 'display_name': 'Neutropenia and Cancer Infections', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12172', 'display_name': 'Neutropenia and Cancer Infections', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12919', 'display_name': 'Blood disorders and treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12167', 'display_name': 'Bacterial Identification and Susceptibility Testing', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neutrophilia', 'display_name': 'Neutrophilia', 'score': 0.92249346}, {'id': 'https://openalex.org/keywords/leukapheresis', 'display_name': 'Leukapheresis', 'score': 0.8495348}, {'id': 'https://openalex.org/keywords/transfusion-therapy', 'display_name': 'Transfusion Therapy', 'score': 0.553086}], 'concepts': [{'id': 'https://openalex.org/C2777802486', 'wikidata': 'https://www.wikidata.org/wiki/Q491741', 'display_name': 'Neutrophilia', 'level': 2, 'score': 0.92249346}, {'id': 'https://openalex.org/C2777983669', 'wikidata': 'https://www.wikidata.org/wiki/Q223143', 'display_name': 'Granulocyte', 'level': 2, 'score': 0.91577613}, {'id': 'https://openalex.org/C2777371436', 'wikidata': 'https://www.wikidata.org/wiki/Q3237071', 'display_name': 'Leukapheresis', 'level': 4, 'score': 0.8495348}, {'id': 'https://openalex.org/C2777767877', 'wikidata': 'https://www.wikidata.org/wiki/Q419327', 'display_name': 'Granulocyte colony-stimulating factor', 'level': 3, 'score': 0.8424611}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7127438}, {'id': 'https://openalex.org/C2779817106', 'wikidata': 'https://www.wikidata.org/wiki/Q7834210', 'display_name': 'Transfusion therapy', 'level': 3, 'score': 0.553086}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4986229}, {'id': 'https://openalex.org/C2780014101', 'wikidata': 'https://www.wikidata.org/wiki/Q183605', 'display_name': 'Blood transfusion', 'level': 2, 'score': 0.317928}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.31067193}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.30586576}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14738214}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.07755214}, {'id': 'https://openalex.org/C10205521', 'wikidata': 'https://www.wikidata.org/wiki/Q4035578', 'display_name': 'CD34', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016913', 'descriptor_name': 'Blood Component Transfusion', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D016179', 'descriptor_name': 'Granulocyte Colony-Stimulating Factor', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D006098', 'descriptor_name': 'Granulocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D019650', 'descriptor_name': 'Hematopoietic Stem Cell Mobilization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016913', 'descriptor_name': 'Blood Component Transfusion', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D016913', 'descriptor_name': 'Blood Component Transfusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001782', 'descriptor_name': 'Blood Donors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016179', 'descriptor_name': 'Granulocyte Colony-Stimulating Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006098', 'descriptor_name': 'Granulocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007958', 'descriptor_name': 'Leukocyte Count', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D007958', 'descriptor_name': 'Leukocyte Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009504', 'descriptor_name': 'Neutrophils', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009504', 'descriptor_name': 'Neutrophils', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00062752-199811000-00007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S15004046', 'display_name': 'Current Opinion in Hematology', 'issn_l': '1065-6251', 'issn': ['1065-6251', '1080-8213', '1531-7048'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9814645', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.74}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2412200985', 'https://openalex.org/W2409655596', 'https://openalex.org/W2325369164', 'https://openalex.org/W2318813781', 'https://openalex.org/W2314217129', 'https://openalex.org/W2163634077', 'https://openalex.org/W2145312869', 'https://openalex.org/W2106803404', 'https://openalex.org/W2078288268', 'https://openalex.org/W2008675714'], 'abstract_inverted_index': {'Granulocyte': [0], 'transfusion': [1, 90, 185], 'therapy': [2, 186], 'has': [3, 27, 36, 53, 187], 'been': [4, 29, 37, 54, 174, 188], 'used': [5], 'infrequently': [6], 'in': [7, 14, 20, 68, 86, 122, 150], 'the': [8, 21, 41, 44, 57, 73, 156, 176], 'last': [9], '10': [10], 'to': [11, 40, 65, 117, 132, 167, 190], '15': [12], 'years,': [13], 'large': [15, 126], 'part': [16], 'because': [17], 'its': [18], 'efficacy': [19, 35, 178], 'treatment': [22], 'of': [23, 34, 46, 59, 75, 89, 159, 179, 183], 'infected': [24], 'neutropenic': [25], 'patients': [26, 123], 'not': [28], 'impressive.': [30], 'This': [31], 'perceived': [32], 'lack': [33], 'attributed': [38], 'primarily': [39], 'fact': [42], 'that': [43, 77, 96, 111, 155], 'dose': [45], 'granulocytes': [47, 76, 160], 'obtainable': [48], 'with': [49, 98, 100], 'standard': [50], 'leukapheresis': [51], 'techniques': [52], 'inadequate.': [55], 'With': [56], 'availability': [58], 'recombinant': [60], 'granulocyte': [61, 112, 184], 'colony-stimulating': [62], 'factor': [63], '(G-CSF)': [64], 'stimulate': [66], 'neutrophilia': [67], 'normal': [69, 108, 133, 136], 'donors': [70, 109, 165], 'and': [71, 110, 138, 149], 'increase': [72], 'number': [74], 'can': [78], 'be': [79, 168, 191], 'collected,': [80], 'there': [81], 'is': [82, 104], 'now': [83], 'renewed': [84], 'interest': [85], 'this': [87, 180], 'form': [88], 'therapy.': [91], 'Recent': [92], 'studies': [93], 'have': [94, 153, 173], 'shown': [95, 154], 'stimulation': [97], 'G-CSF,': [99], 'or': [101, 134, 145], 'without': [102], 'corticosteroids,': [103], 'well': [105], 'tolerated': [106], 'by': [107], 'yields': [113], 'are': [114], 'increased': [115], 'three-': [116], 'four-fold.': [118], 'Blood': [119], 'neutrophil': [120], 'counts': [121], 'receiving': [124], 'these': [125], 'cell': [127], 'doses': [128], 'rise': [129], 'substantially,': [130], 'often': [131], 'near': [135], 'levels,': [137], 'commonly': [139], 'remain': [140], 'elevated': [141], 'for': [142], '24': [143], 'hours': [144], 'more.': [146], 'In': [147], 'vitro': [148], 'vivo': [151], 'measurements': [152], 'functional': [157], 'capabilities': [158], 'collected': [161], 'from': [162], 'G-CSF': [163], 'stimulated': [164], 'appear': [166], 'normal.': [169], 'Although': [170], 'early': [171], 'reports': [172], 'encouraging,': [175], 'clinical': [177], 'new': [181], 'level': [182], 'yet': [189], 'determined.': [192]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2106803404', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-10T03:18:06.308826', 'created_date': '2016-06-24'}