Title: Total Synthesis and Structural Reassignment of the γ‐Lactone Polyketide from <i>Diaporthe</i> sp. SXZ‐19
Abstract: Abstract The first stereoselective total synthesis of the proposed structure of the γ‐lactone from Diaporthe sp. SXZ‐19 was achieved by utilizing a convergent pathway. The four stereogenic centers were formed by employing Brown's asymmetric alkoxyallylboration reaction, and a cross‐metathesis reaction was used to construct the trans double bond of the γ‐lactone side chain. This synthesis led to a revision of proposed structural assignment of the natural product.
Publication Year: 2015
Publication Date: 2015-09-30
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 5
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