Title: Stereoselective total synthesis of polyketide lactone, (3R,4S,5S,9S)-3,5,9-trihydroxy-4-methylundecanoic acid δ-lactone
Abstract: The total synthesis of lactone 1 has been described. The convergent asymmetric synthesis relies on the use of an Evans' syn-aldol, chain extension with lithio tert-butyl acetate, and the stereoselective reduction of a ketone as the key reactions.
Publication Year: 2009
Publication Date: 2009-07-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 10
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