Publication Information

{'id': 'https://openalex.org/W2103926307', 'doi': 'https://doi.org/10.1523/jneurosci.19-23-10193.1999', 'title': 'Glutamate Induces Rapid Upregulation of Astrocyte Glutamate Transport and Cell-Surface Expression of GLAST', 'display_name': 'Glutamate Induces Rapid Upregulation of Astrocyte Glutamate Transport and Cell-Surface Expression of GLAST', 'publication_year': 1999, 'publication_date': '1999-12-01', 'ids': {'openalex': 'https://openalex.org/W2103926307', 'doi': 'https://doi.org/10.1523/jneurosci.19-23-10193.1999', 'mag': '2103926307', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10575016', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6782431'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.19-23-10193.1999', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/19/23/10193.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.jneurosci.org/content/jneuro/19/23/10193.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001122900', 'display_name': 'Shumin Duan', 'orcid': 'https://orcid.org/0000-0002-0466-1821'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shumin Duan', 'raw_affiliation_strings': ['Department of Neurology,  University of California San Francisco,  USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology,  University of California San Francisco,  USA.', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003587956', 'display_name': 'Christopher M. Anderson', 'orcid': 'https://orcid.org/0000-0003-0678-3002'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christopher M. Anderson', 'raw_affiliation_strings': ['Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121', 'institution_ids': ['https://openalex.org/I180670191', 'https://openalex.org/I1315708478']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051876812', 'display_name': 'Becky A. Stein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Becky A. Stein', 'raw_affiliation_strings': ['Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022193976', 'display_name': 'Raymond A. Swanson', 'orcid': 'https://orcid.org/0000-0002-3664-5359'}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Raymond A. Swanson', 'raw_affiliation_strings': ['Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University of California, San Francisco and Veterans Affairs Medical Center, San Francisco, California 94121', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.179, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 307, 'citation_normalized_percentile': {'value': 0.9471, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '19', 'issue': '23', 'first_page': '10193', 'last_page': '10200'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12770', 'display_name': 'Amino Acid Enzymes and Metabolism', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777542381', 'wikidata': 'https://www.wikidata.org/wiki/Q502961', 'display_name': 'Astrocyte', 'level': 3, 'score': 0.84629834}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.8311982}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.81146705}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6096188}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.56058365}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5385607}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26638412}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16960564}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.13366082}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.06897062}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018698', 'descriptor_name': 'Glutamic Acid', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D017981', 'descriptor_name': 'Receptors, Neurotransmitter', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D027322', 'descriptor_name': 'Amino Acid Transport System X-AG', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001253', 'descriptor_name': 'Astrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003571', 'descriptor_name': 'Cytochalasin B', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003571', 'descriptor_name': 'Cytochalasin B', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015638', 'descriptor_name': 'Cytochalasin D', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015638', 'descriptor_name': 'Cytochalasin D', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D027342', 'descriptor_name': 'Excitatory Amino Acid Transporter 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018698', 'descriptor_name': 'Glutamic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018698', 'descriptor_name': 'Glutamic Acid', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017470', 'descriptor_name': 'Receptors, Glutamate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017470', 'descriptor_name': 'Receptors, Glutamate', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D017981', 'descriptor_name': 'Receptors, Neurotransmitter', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017981', 'descriptor_name': 'Receptors, Neurotransmitter', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.19-23-10193.1999', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/19/23/10193.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6782431', 'pdf_url': 'https://europepmc.org/articles/pmc6782431?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782431', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10575016', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.19-23-10193.1999', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/19/23/10193.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W124246603', 'https://openalex.org/W1491108164', 'https://openalex.org/W1555637041', 'https://openalex.org/W1607257685', 'https://openalex.org/W1629378997', 'https://openalex.org/W1712871378', 'https://openalex.org/W1755902553', 'https://openalex.org/W1773423646', 'https://openalex.org/W1900295716', 'https://openalex.org/W1911240071', 'https://openalex.org/W1922739097', 'https://openalex.org/W1965902234', 'https://openalex.org/W1977634657', 'https://openalex.org/W1979146576', 'https://openalex.org/W1988807285', 'https://openalex.org/W1995573855', 'https://openalex.org/W2003410399', 'https://openalex.org/W2005599435', 'https://openalex.org/W2005725623', 'https://openalex.org/W2008189718', 'https://openalex.org/W2014856221', 'https://openalex.org/W2015068634', 'https://openalex.org/W2015799458', 'https://openalex.org/W2016575029', 'https://openalex.org/W2018975189', 'https://openalex.org/W2026307239', 'https://openalex.org/W2039723960', 'https://openalex.org/W2045192497', 'https://openalex.org/W2054683291', 'https://openalex.org/W2058948754', 'https://openalex.org/W2066400644', 'https://openalex.org/W2067993656', 'https://openalex.org/W2084900570', 'https://openalex.org/W2086731122', 'https://openalex.org/W2091306165', 'https://openalex.org/W2096791952', 'https://openalex.org/W2104400385', 'https://openalex.org/W2109449392', 'https://openalex.org/W2114745427', 'https://openalex.org/W2128744963', 'https://openalex.org/W2135662935', 'https://openalex.org/W2136414262', 'https://openalex.org/W2147739392', 'https://openalex.org/W2153315387', 'https://openalex.org/W2157853053', 'https://openalex.org/W2160228434', 'https://openalex.org/W2160644313', 'https://openalex.org/W2161452179', 'https://openalex.org/W2403978899', 'https://openalex.org/W2419482464', 'https://openalex.org/W2888802558'], 'related_works': ['https://openalex.org/W582905479', 'https://openalex.org/W2996239022', 'https://openalex.org/W2592007767', 'https://openalex.org/W2116447221', 'https://openalex.org/W2094467039', 'https://openalex.org/W2080599553', 'https://openalex.org/W2026862129', 'https://openalex.org/W1976265701', 'https://openalex.org/W1930507751', 'https://openalex.org/W1896952141'], 'abstract_inverted_index': {'Glutamate': [0, 65], 'transporters': [1], 'clear': [2], 'glutamate': [3, 16, 43, 46, 70, 91, 102, 121, 125, 143, 169, 179, 205, 229, 235], 'from': [4], 'the': [5, 57, 139, 156, 165, 188, 215], 'extracellular': [6, 228], 'space': [7], 'by': [8, 39, 109, 119, 146, 204, 210, 224], 'high-affinity': [9], 'binding': [10], 'and': [11, 19, 30, 60, 77, 92, 213], 'uptake.': [12, 170], 'Factors': [13], 'that': [14, 55, 138, 178, 195], 'regulate': [15], 'transporter': [17, 40, 63, 115, 148], 'expression': [18, 186, 197], 'activity': [20, 149, 212], 'can': [21, 200], 'thereby': [22], 'influence': [23], 'excitatory': [24], 'neurotransmission.': [25], 'Transporter': [26], 'function': [27], 'in': [28, 74, 133, 168, 184, 227], 'GABAergic': [29], 'other': [31], 'systems': [32], 'has': [33], 'been': [34], 'shown': [35], 'to': [36, 68], 'be': [37, 201], 'regulated': [38, 203], 'substrates.': [41], 'Here,': [42], 'regulation': [44], 'of': [45, 88, 101, 142, 173, 198], 'transport': [47, 71, 130, 236], 'was': [48, 66, 83, 107], 'studied': [49], 'using': [50], 'primary': [51], 'murine': [52], 'astrocyte': [53, 189, 234], 'cultures': [54], 'express': [56], 'GLAST': [58, 185, 199, 211], '(EAAT1)': [59], 'GLT-1': [61], '(EAAT2)': [62], 'subtypes.': [64], 'found': [67], 'stimulate': [69, 129], 'capacity': [72], '(V(max))': [73], 'a': [75, 114, 134, 207, 222], 'dose-': [76], 'time-dependent': [78], 'manner.': [79], 'The': [80, 104], 'maximal': [81], 'increase': [82, 167, 183], '100%,': [84], 'with': [85, 93, 155], 'an': [86, 182], 'ED(50)': [87], '40': [89], 'microM': [90], 'onset': [94, 100], 'beginning': [95], 'approximately': [96], '15': [97], 'min': [98], 'after': [99], 'exposure.': [103], 'uptake': [105], 'stimulation': [106], 'reproduced': [108], 'D-aspartate,': [110], 'which': [111, 225], 'is': [112, 144], 'also': [113], 'substrate,': [116], 'but': [117], 'not': [118, 128], 'nontransported': [120], 'receptor': [122, 152], 'agonists.': [123], 'Moreover,': [124], 'incubation': [126, 180], 'did': [127], 'when': [131], 'performed': [132], 'sodium-free': [135], 'medium,': [136], 'suggesting': [137], 'stimulatory': [140], 'effect': [141], 'triggered': [145, 209], 'increased': [147], 'rather': [150], 'than': [151], 'activation.': [153], 'Treatment': [154], 'actin-disrupting': [157], 'agents': [158], 'cytochalasin': [159, 162], 'B': [160], 'or': [161], 'D': [163], 'prevented': [164], 'glutamate-induced': [166], 'Biotinylation': [171], 'labeling': [172], 'membrane': [174], 'surface': [175], 'proteins': [176], 'showed': [177], 'produced': [181], 'at': [187], 'cell': [190], 'surface.': [191], 'These': [192], 'results': [193], 'suggest': [194], 'cell-surface': [196], 'rapidly': [202, 232], 'through': [206], 'process': [208], 'involving': [214], 'actin': [216], 'cytoskeleton.': [217], 'This': [218], 'feedback': [219], 'loop': [220], 'provides': [221], 'mechanism': [223], 'changes': [226], 'concentrations': [230], 'could': [231], 'modulate': [233], 'capacity.': [237]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2103926307', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-08T22:55:55.572497', 'created_date': '2016-06-24'}