Early Virologic Nonresponse to Tenofovir, Abacavir, and Lamivudine in HIV‐Infected Antiretroviral‐Naive Subjects

Name: Work Video:
Duration: 3 min 30 s
Description: BackgroundAntiretroviral combinations that reduce the number of pills and dosing frequency have the potential to simplify therapy. We compared 2 regimens dosed as 2 pills once daily
Joel E. Gallant; Allan Rodríguez; Winkler G. Weinberg; Benjamin Young; Daniel S Berger; Michael L. Lim; Qiming Liao; Lisa Ross; Judy Johnson; Mark S. Shaefer
{'id': 'https://openalex.org/W2096070610', 'doi': 'https://doi.org/10.1086/498069', 'title': 'Early Virologic Nonresponse to Tenofovir, Abacavir, and Lamivudine in HIV‐Infected Antiretroviral‐Naive Subjects', 'display_name': 'Early Virologic Nonresponse to Tenofovir, Abacavir, and Lamivudine in HIV‐Infected Antiretroviral‐Naive Subjects', 'publication_year': 2005, 'publication_date': '2005-11-03', 'ids': {'openalex': 'https://openalex.org/W2096070610', 'doi': 'https://doi.org/10.1086/498069', 'mag': '2096070610', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16267763'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1086/498069', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/192/11/1921/6464760/192-11-1921.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/jid/article-pdf/192/11/1921/6464760/192-11-1921.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048477426', 'display_name': 'Joel E. Gallant', 'orcid': 'https://orcid.org/0000-0002-7144-1642'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joel\xa0E. Gallant', 'raw_affiliation_strings': ['Division of Infectious Diseases, Johns Hopkins University School of Medicine , Baltimore, Maryland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Infectious Diseases, Johns Hopkins University School of Medicine , Baltimore, Maryland.', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015290437', 'display_name': 'Allan Rodríguez', 'orcid': 'https://orcid.org/0000-0001-9477-3327'}, 'institutions': [{'id': 'https://openalex.org/I145608581', 'display_name': 'University of Miami', 'ror': 'https://ror.org/02dgjyy92', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145608581']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Allan\xa0E. Rodriguez', 'raw_affiliation_strings': ['University of Miami, Miami, Florida.'], 'affiliations': [{'raw_affiliation_string': 'University of Miami, Miami, Florida.', 'institution_ids': ['https://openalex.org/I145608581']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053516032', 'display_name': 'Winkler G. Weinberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1343052199', 'display_name': 'Kaiser Permanente', 'ror': 'https://ror.org/00t60zh31', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1343052199']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Winkler\xa0G. Weinberg', 'raw_affiliation_strings': ['Kaiser Permanente'], 'affiliations': [{'raw_affiliation_string': 'Kaiser Permanente', 'institution_ids': ['https://openalex.org/I1343052199']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101552771', 'display_name': 'Benjamin Young', 'orcid': 'https://orcid.org/0009-0009-2760-350X'}, 'institutions': [{'id': 'https://openalex.org/I921990950', 'display_name': 'University of Colorado Denver', 'ror': 'https://ror.org/02hh7en24', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I921990950']}, {'id': 'https://openalex.org/I2802547023', 'display_name': 'Rose Medical Center', 'ror': 'https://ror.org/055y34y19', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802547023']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Benjamin Young', 'raw_affiliation_strings': ['Rose Medical Center.'], 'affiliations': [{'raw_affiliation_string': 'Rose Medical Center.', 'institution_ids': ['https://openalex.org/I921990950', 'https://openalex.org/I2802547023']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103693249', 'display_name': 'Daniel S Berger', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Daniel\xa0S. Berger', 'raw_affiliation_strings': ['Northstar Medical Center'], 'affiliations': [{'raw_affiliation_string': 'Northstar Medical Center', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103572181', 'display_name': 'Michael L. Lim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210156610', 'display_name': 'GlaxoSmithKline (Netherlands)', 'ror': 'https://ror.org/05atcw115', 'country_code': 'NL', 'type': 'company', 'lineage': ['https://openalex.org/I188950975', 'https://openalex.org/I4210156610']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Michael\xa0L. Lim', 'raw_affiliation_strings': ['GlaxoSmithKline'], 'affiliations': [{'raw_affiliation_string': 'GlaxoSmithKline', 'institution_ids': ['https://openalex.org/I4210156610']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088607533', 'display_name': 'Qiming Liao', 'orcid': 'https://orcid.org/0000-0001-5822-2739'}, 'institutions': [{'id': 'https://openalex.org/I4210156610', 'display_name': 'GlaxoSmithKline (Netherlands)', 'ror': 'https://ror.org/05atcw115', 'country_code': 'NL', 'type': 'company', 'lineage': ['https://openalex.org/I188950975', 'https://openalex.org/I4210156610']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Qiming Liao', 'raw_affiliation_strings': ['GlaxoSmithKline'], 'affiliations': [{'raw_affiliation_string': 'GlaxoSmithKline', 'institution_ids': ['https://openalex.org/I4210156610']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069581471', 'display_name': 'Lisa Ross', 'orcid': 'https://orcid.org/0000-0001-7388-2655'}, 'institutions': [{'id': 'https://openalex.org/I4210156610', 'display_name': 'GlaxoSmithKline (Netherlands)', 'ror': 'https://ror.org/05atcw115', 'country_code': 'NL', 'type': 'company', 'lineage': ['https://openalex.org/I188950975', 'https://openalex.org/I4210156610']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Lisa Ross', 'raw_affiliation_strings': ['GlaxoSmithKline'], 'affiliations': [{'raw_affiliation_string': 'GlaxoSmithKline', 'institution_ids': ['https://openalex.org/I4210156610']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113532202', 'display_name': 'Judy Johnson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210156610', 'display_name': 'GlaxoSmithKline (Netherlands)', 'ror': 'https://ror.org/05atcw115', 'country_code': 'NL', 'type': 'company', 'lineage': ['https://openalex.org/I188950975', 'https://openalex.org/I4210156610']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Judy Johnson', 'raw_affiliation_strings': ['GlaxoSmithKline'], 'affiliations': [{'raw_affiliation_string': 'GlaxoSmithKline', 'institution_ids': ['https://openalex.org/I4210156610']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079973774', 'display_name': 'Mark S. Shaefer', 'orcid': 'https://orcid.org/0000-0002-0545-7304'}, 'institutions': [{'id': 'https://openalex.org/I4210156610', 'display_name': 'GlaxoSmithKline (Netherlands)', 'ror': 'https://ror.org/05atcw115', 'country_code': 'NL', 'type': 'company', 'lineage': ['https://openalex.org/I188950975', 'https://openalex.org/I4210156610']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Mark\xa0S. Shaefer', 'raw_affiliation_strings': ['GlaxoSmithKline'], 'affiliations': [{'raw_affiliation_string': 'GlaxoSmithKline', 'institution_ids': ['https://openalex.org/I4210156610']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 11.426, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 146, 'citation_normalized_percentile': {'value': 0.81111, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '192', 'issue': '11', 'first_page': '1921', 'last_page': '1930'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10082', 'display_name': 'HIV/AIDS Research and Interventions', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/abacavir', 'display_name': 'Abacavir', 'score': 0.93524855}, {'id': 'https://openalex.org/keywords/tenofovir', 'display_name': 'Tenofovir', 'score': 0.691996}, {'id': 'https://openalex.org/keywords/antiretroviral-drug', 'display_name': 'Antiretroviral drug', 'score': 0.48748422}, {'id': 'https://openalex.org/keywords/antiretroviral-treatment', 'display_name': 'Antiretroviral treatment', 'score': 0.44180024}, {'id': 'https://openalex.org/keywords/reverse-transcriptase-inhibitor', 'display_name': 'Reverse-transcriptase inhibitor', 'score': 0.42116493}], 'concepts': [{'id': 'https://openalex.org/C2779465607', 'wikidata': 'https://www.wikidata.org/wiki/Q304330', 'display_name': 'Abacavir', 'level': 5, 'score': 0.93524855}, {'id': 'https://openalex.org/C2777869810', 'wikidata': 'https://www.wikidata.org/wiki/Q422631', 'display_name': 'Lamivudine', 'level': 4, 'score': 0.8473255}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.7204695}, {'id': 'https://openalex.org/C2779344132', 'wikidata': 'https://www.wikidata.org/wiki/Q155954', 'display_name': 'Tenofovir', 'level': 3, 'score': 0.691996}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6198167}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.5834384}, {'id': 'https://openalex.org/C3018457394', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral drug', 'level': 5, 'score': 0.48748422}, {'id': 'https://openalex.org/C3019165603', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral treatment', 'level': 5, 'score': 0.44180024}, {'id': 'https://openalex.org/C2777351918', 'wikidata': 'https://www.wikidata.org/wiki/Q421559', 'display_name': 'Reverse-transcriptase inhibitor', 'level': 5, 'score': 0.42116493}, {'id': 'https://openalex.org/C2776452011', 'wikidata': 'https://www.wikidata.org/wiki/Q311463', 'display_name': 'Sida', 'level': 4, 'score': 0.34787995}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.32273856}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.29105842}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.27205122}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.15678927}, {'id': 'https://openalex.org/C2780593183', 'wikidata': 'https://www.wikidata.org/wiki/Q6844', 'display_name': 'Hepatitis B virus', 'level': 3, 'score': 0.06919101}], 'mesh': [{'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015224', 'descriptor_name': 'Dideoxynucleosides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D018894', 'descriptor_name': 'Reverse Transcriptase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018791', 'descriptor_name': 'CD4 Lymphocyte Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015224', 'descriptor_name': 'Dideoxynucleosides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024882', 'descriptor_name': 'Drug Resistance, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024882', 'descriptor_name': 'Drug Resistance, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018894', 'descriptor_name': 'Reverse Transcriptase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068698', 'descriptor_name': 'Tenofovir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017211', 'descriptor_name': 'Treatment Failure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1086/498069', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/192/11/1921/6464760/192-11-1921.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16267763', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1086/498069', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/192/11/1921/6464760/192-11-1921.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W131658343', 'https://openalex.org/W1971758213', 'https://openalex.org/W1973787553', 'https://openalex.org/W1978540833', 'https://openalex.org/W1993086185', 'https://openalex.org/W2021037491', 'https://openalex.org/W2023257490', 'https://openalex.org/W2042823706', 'https://openalex.org/W2052332986', 'https://openalex.org/W2061857819', 'https://openalex.org/W2083477796', 'https://openalex.org/W2093590894', 'https://openalex.org/W2104451608', 'https://openalex.org/W2129710521', 'https://openalex.org/W2136873830', 'https://openalex.org/W2146329405', 'https://openalex.org/W2183940924', 'https://openalex.org/W2318289184'], 'related_works': ['https://openalex.org/W4318915823', 'https://openalex.org/W4297927387', 'https://openalex.org/W3204092768', 'https://openalex.org/W2610820740', 'https://openalex.org/W2415396486', 'https://openalex.org/W2189516800', 'https://openalex.org/W2135690881', 'https://openalex.org/W2096070610', 'https://openalex.org/W2076099704', 'https://openalex.org/W2031758758'], 'abstract_inverted_index': {'BackgroundAntiretroviral': [0], 'combinations': [1], 'that': [2], 'reduce': [3], 'the': [4, 12], 'number': [5], 'of': [6], 'pills': [7, 24], 'and': [8], 'dosing': [9], 'frequency': [10], 'have': [11], 'potential': [13], 'to': [14], 'simplify': [15], 'therapy.': [16], 'We': [17], 'compared': [18], '2': [19, 23], 'regimens': [20], 'dosed': [21], 'as': [22], 'once': [25], 'daily': [26]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2096070610', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-24T09:07:53.301856', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
